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GTF2I (general transcription factor IIi)

Identity

Alias (NCBI)BAP135
BTKAP1
DIWS
GTFII-I
IB291
SPIN
TFII-I
WBS
WBSCR6
HGNC (Hugo) GTF2I
HGNC Alias symbTFII-I
BAP-135
SPIN
BTKAP1
DIWS
IB291
HGNC Previous nameWBSCR6
HGNC Previous namegeneral transcription factor II, i
LocusID (NCBI) 2969
Atlas_Id 51639
Location 7q11.23  [Link to chromosome band 7q11]
Location_base_pair Starts at 74657718 and ends at 74760692 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKHD1-EIF4EBP3 (5q31.3) / GTF2I (7q11.23)EIF4H (7q11.23) / GTF2I (7q11.23)GTF2I (7q11.23) / CLIP2 (7q11.23)
GTF2I (7q11.23) / GTF2I (7q11.23)GTF2I (7q11.23) / NCL (2q37.1)GTF2I (7q11.23) / NCOA2 (8q13.3)
GTF2I (7q11.23) / PGPEP1 (19p13.11)GTF2I (7q11.23) / RARA (17q21.2)ANKHD1-EIF4EBP3 5q31.3 / GTF2I 7q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  M3/M3v acute myeloid leukemia (AML M3/M3v)
::Acute promyelocytic leukemia (APL)
::Acute promyelocytic leukemia (APL) PML/RARA

t(7;17)(q11;q21) GTF2I/RARA in APL


External links

Nomenclature
HGNC (Hugo)GTF2I   4659
Cards
Entrez_Gene (NCBI)GTF2I    general transcription factor IIi
AliasesBAP135; BTKAP1; DIWS; GTFII-I; 
IB291; SPIN; TFII-I; WBS; WBSCR6
GeneCards (Weizmann)GTF2I
Ensembl hg19 (Hinxton)ENSG00000263001 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000263001 [Gene_View]  ENSG00000263001 [Sequence]  chr7:74657718-74760692 [Contig_View]  GTF2I [Vega]
ICGC DataPortalENSG00000263001
TCGA cBioPortalGTF2I
AceView (NCBI)GTF2I
Genatlas (Paris)GTF2I
SOURCE (Princeton)GTF2I
Genetics Home Reference (NIH)GTF2I
Genomic and cartography
GoldenPath hg38 (UCSC)GTF2I  -     chr7:74657718-74760692 +  7q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF2I  -     7q11.23   [Description]    (hg19-Feb_2009)
GoldenPathGTF2I - 7q11.23 [CytoView hg19]  GTF2I - 7q11.23 [CytoView hg38]
ImmunoBaseENSG00000263001
Genome Data Viewer NCBIGTF2I [Mapview hg19]  
OMIM601679   
Gene and transcription
Genbank (Entrez)AA641906 AF015553 AF035737 AF038967 AF038968
RefSeq transcript (Entrez)NM_001163636 NM_001280800 NM_001518 NM_032999 NM_033000 NM_033001
Consensus coding sequences : CCDS (NCBI)GTF2I
Gene ExpressionGTF2I [ NCBI-GEO ]   GTF2I [ EBI - ARRAY_EXPRESS ]   GTF2I [ SEEK ]   GTF2I [ MEM ]
Gene Expression Viewer (FireBrowse)GTF2I [ Firebrowse - Broad ]
GenevisibleExpression of GTF2I in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2969
GTEX Portal (Tissue expression)GTF2I
Human Protein AtlasENSG00000263001-GTF2I [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GTF2I
Human Protein Atlas [tissue]ENSG00000263001-GTF2I [tissue]
HPRD03399
Protein Interaction databases
BioGRIDGTF2I
STRING (EMBL)GTF2I
ZODIACGTF2I
Ontologies - Pathways
Litterature
PubMed230 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGTF2I
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:11:44 CEST 2021

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