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GTF3C1 (general transcription factor IIIC subunit 1)

Identity

Alias_namesgeneral transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD )
general transcription factor IIIC, polypeptide 1, alpha 220kDa
Alias_symbol (synonym)TFIIIC220
Other aliasTFIIIC
TFIIICalpha
HGNC (Hugo) GTF3C1
LocusID (NCBI) 2975
Atlas_Id 64094
Location 16p12.1  [Link to chromosome band 16p12]
Location_base_pair Starts at 27460613 and ends at 27549930 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GTF3C1 (16p12.1) / GH1 (17q23.3)GTF3C1 (16p12.1) / MKI67 (10q26.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GTF3C1   4664
Cards
Entrez_Gene (NCBI)GTF3C1  2975  general transcription factor IIIC subunit 1
AliasesTFIIIC; TFIIIC220; TFIIICalpha
GeneCards (Weizmann)GTF3C1
Ensembl hg19 (Hinxton)ENSG00000077235 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000077235 [Gene_View]  chr16:27460613-27549930 [Contig_View]  GTF3C1 [Vega]
ICGC DataPortalENSG00000077235
TCGA cBioPortalGTF3C1
AceView (NCBI)GTF3C1
Genatlas (Paris)GTF3C1
WikiGenes2975
SOURCE (Princeton)GTF3C1
Genetics Home Reference (NIH)GTF3C1
Genomic and cartography
GoldenPath hg38 (UCSC)GTF3C1  -     chr16:27460613-27549930 -  16p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF3C1  -     16p12.1   [Description]    (hg19-Feb_2009)
EnsemblGTF3C1 - 16p12.1 [CytoView hg19]  GTF3C1 - 16p12.1 [CytoView hg38]
Mapping of homologs : NCBIGTF3C1 [Mapview hg19]  GTF3C1 [Mapview hg38]
OMIM603246   
Gene and transcription
Genbank (Entrez)AK091032 AK123999 AK131479 BC044857 BC052642
RefSeq transcript (Entrez)NM_001286242 NM_001520
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTF3C1
Cluster EST : UnigeneHs.371718 [ NCBI ]
CGAP (NCI)Hs.371718
Alternative Splicing GalleryENSG00000077235
Gene ExpressionGTF3C1 [ NCBI-GEO ]   GTF3C1 [ EBI - ARRAY_EXPRESS ]   GTF3C1 [ SEEK ]   GTF3C1 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF3C1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2975
GTEX Portal (Tissue expression)GTF3C1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12789   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12789  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12789
Splice isoforms : SwissVarQ12789
PhosPhoSitePlusQ12789
Domains : Interpro (EBI)TFIIIC_Bblock-bd   
Domain families : Pfam (Sanger)B-block_TFIIIC (PF04182)   
Domain families : Pfam (NCBI)pfam04182   
Conserved Domain (NCBI)GTF3C1
DMDM Disease mutations2975
Blocks (Seattle)GTF3C1
SuperfamilyQ12789
Human Protein AtlasENSG00000077235
Peptide AtlasQ12789
HPRD07540
IPIIPI00414482   IPI00807491   IPI00874274   
Protein Interaction databases
DIP (DOE-UCLA)Q12789
IntAct (EBI)Q12789
FunCoupENSG00000077235
BioGRIDGTF3C1
STRING (EMBL)GTF3C1
ZODIACGTF3C1
Ontologies - Pathways
QuickGOQ12789
Ontology : AmiGOtranscription factor TFIIIC complex  transcription factor activity, core RNA polymerase III binding  RNA polymerase III type 1 promoter sequence-specific DNA binding  RNA polymerase III type 2 promoter sequence-specific DNA binding  transcription factor activity, RNA polymerase III transcription factor binding  DNA binding  protein binding  nucleus  nucleoplasm  nucleolus  transcription, DNA-templated  regulation of transcription from RNA polymerase III promoter  transcription from RNA polymerase III promoter  transcription initiation from RNA polymerase III promoter  rRNA transcription  tRNA transcription  membrane  intracellular ribonucleoprotein complex  5S class rRNA transcription from RNA polymerase III type 1 promoter  5S class rRNA transcription from RNA polymerase III type 1 promoter  tRNA transcription from RNA polymerase III promoter  
Ontology : EGO-EBItranscription factor TFIIIC complex  transcription factor activity, core RNA polymerase III binding  RNA polymerase III type 1 promoter sequence-specific DNA binding  RNA polymerase III type 2 promoter sequence-specific DNA binding  transcription factor activity, RNA polymerase III transcription factor binding  DNA binding  protein binding  nucleus  nucleoplasm  nucleolus  transcription, DNA-templated  regulation of transcription from RNA polymerase III promoter  transcription from RNA polymerase III promoter  transcription initiation from RNA polymerase III promoter  rRNA transcription  tRNA transcription  membrane  intracellular ribonucleoprotein complex  5S class rRNA transcription from RNA polymerase III type 1 promoter  5S class rRNA transcription from RNA polymerase III type 1 promoter  tRNA transcription from RNA polymerase III promoter  
Pathways : BIOCARTARNA polymerase III transcription [Genes]   
NDEx NetworkGTF3C1
Atlas of Cancer Signalling NetworkGTF3C1
Wikipedia pathwaysGTF3C1
Orthology - Evolution
OrthoDB2975
GeneTree (enSembl)ENSG00000077235
Phylogenetic Trees/Animal Genes : TreeFamGTF3C1
HOVERGENQ12789
HOGENOMQ12789
Homologs : HomoloGeneGTF3C1
Homology/Alignments : Family Browser (UCSC)GTF3C1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF3C1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF3C1
dbVarGTF3C1
ClinVarGTF3C1
1000_GenomesGTF3C1 
Exome Variant ServerGTF3C1
ExAC (Exome Aggregation Consortium)GTF3C1 (select the gene name)
Genetic variants : HAPMAP2975
Genomic Variants (DGV)GTF3C1 [DGVbeta]
DECIPHERGTF3C1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTF3C1 
Mutations
ICGC Data PortalGTF3C1 
TCGA Data PortalGTF3C1 
Broad Tumor PortalGTF3C1
OASIS PortalGTF3C1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF3C1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTF3C1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTF3C1
DgiDB (Drug Gene Interaction Database)GTF3C1
DoCM (Curated mutations)GTF3C1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTF3C1 (select a term)
intoGenGTF3C1
Cancer3DGTF3C1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603246   
Orphanet
MedgenGTF3C1
Genetic Testing Registry GTF3C1
NextProtQ12789 [Medical]
TSGene2975
GENETestsGTF3C1
Target ValidationGTF3C1
Huge Navigator GTF3C1 [HugePedia]
snp3D : Map Gene to Disease2975
BioCentury BCIQGTF3C1
ClinGenGTF3C1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2975
Chemical/Pharm GKB GenePA29052
Clinical trialGTF3C1
Miscellaneous
canSAR (ICR)GTF3C1 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTF3C1
EVEXGTF3C1
GoPubMedGTF3C1
iHOPGTF3C1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:10:03 CEST 2017

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