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GTF3C2 (general transcription factor IIIC subunit 2)

Identity

Alias (NCBI)TF3C-beta
TFIIIC-BETA
TFIIIC110
HGNC (Hugo) GTF3C2
HGNC Alias symbKIAA0011
TFIIIC110
HGNC Previous namegeneral transcription factor IIIC, polypeptide 2 (beta subunit, 110kD)
 general transcription factor IIIC, polypeptide 2, beta 110kDa
LocusID (NCBI) 2976
Atlas_Id 64095
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 27325849 and ends at 27357034 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GTF3C2 (2p23.3) / GTF3C2 (2p23.3)GTF3C2 (2p23.3) / MPV17 (2p23.3)GTF3C2 (2p23.3) / WDR35 (2p24.1)
ITPR2 (12p12.1) / GTF3C2 (2p23.3)LOC100507412 (-) / GTF3C2 (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GTF3C2   4665
Cards
Entrez_Gene (NCBI)GTF3C2    general transcription factor IIIC subunit 2
AliasesTF3C-beta; TFIIIC-BETA; TFIIIC110
GeneCards (Weizmann)GTF3C2
Ensembl hg19 (Hinxton)ENSG00000115207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115207 [Gene_View]  ENSG00000115207 [Sequence]  chr2:27325849-27357034 [Contig_View]  GTF3C2 [Vega]
ICGC DataPortalENSG00000115207
TCGA cBioPortalGTF3C2
AceView (NCBI)GTF3C2
Genatlas (Paris)GTF3C2
SOURCE (Princeton)GTF3C2
Genetics Home Reference (NIH)GTF3C2
Genomic and cartography
GoldenPath hg38 (UCSC)GTF3C2  -     chr2:27325849-27357034 -  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF3C2  -     2p23.3   [Description]    (hg19-Feb_2009)
GoldenPathGTF3C2 - 2p23.3 [CytoView hg19]  GTF3C2 - 2p23.3 [CytoView hg38]
ImmunoBaseENSG00000115207
Genome Data Viewer NCBIGTF3C2 [Mapview hg19]  
OMIM604883   
Gene and transcription
Genbank (Entrez)AF054988 AK307656 BC000212 BC020981 BP249089
RefSeq transcript (Entrez)NM_001035521 NM_001318909 NM_001388380 NM_001394503 NM_001394504 NM_001394505 NM_001394506 NM_001394507 NM_001394508 NM_001394509 NM_001394510 NM_001394511 NM_001394512 NM_001394514 NM_001394515 NM_001394516 NM_001521
Consensus coding sequences : CCDS (NCBI)GTF3C2
Gene ExpressionGTF3C2 [ NCBI-GEO ]   GTF3C2 [ EBI - ARRAY_EXPRESS ]   GTF3C2 [ SEEK ]   GTF3C2 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF3C2 [ Firebrowse - Broad ]
GenevisibleExpression of GTF3C2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2976
GTEX Portal (Tissue expression)GTF3C2
Human Protein AtlasENSG00000115207-GTF3C2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUA4
PhosPhoSitePlusQ8WUA4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)GTF3C2
SuperfamilyQ8WUA4
AlphaFold pdb e-kbQ8WUA4   
Human Protein Atlas [tissue]ENSG00000115207-GTF3C2 [tissue]
HPRD05347
Protein Interaction databases
DIP (DOE-UCLA)Q8WUA4
IntAct (EBI)Q8WUA4
BioGRIDGTF3C2
STRING (EMBL)GTF3C2
ZODIACGTF3C2
Ontologies - Pathways
QuickGOQ8WUA4
Ontology : AmiGOtranscription factor TFIIIC complex  transcription factor TFIIIC complex  DNA binding  protein binding  nucleoplasm  nucleoplasm  transcription by RNA polymerase III  transcription by RNA polymerase III  5S class rRNA transcription by RNA polymerase III  tRNA transcription by RNA polymerase III  
Ontology : EGO-EBItranscription factor TFIIIC complex  transcription factor TFIIIC complex  DNA binding  protein binding  nucleoplasm  nucleoplasm  transcription by RNA polymerase III  transcription by RNA polymerase III  5S class rRNA transcription by RNA polymerase III  tRNA transcription by RNA polymerase III  
NDEx NetworkGTF3C2
Atlas of Cancer Signalling NetworkGTF3C2
Wikipedia pathwaysGTF3C2
Orthology - Evolution
OrthoDB2976
GeneTree (enSembl)ENSG00000115207
Phylogenetic Trees/Animal Genes : TreeFamGTF3C2
Homologs : HomoloGeneGTF3C2
Homology/Alignments : Family Browser (UCSC)GTF3C2
Gene fusions - Rearrangements
Fusion : QuiverGTF3C2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF3C2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF3C2
dbVarGTF3C2
ClinVarGTF3C2
MonarchGTF3C2
1000_GenomesGTF3C2 
Exome Variant ServerGTF3C2
GNOMAD BrowserENSG00000115207
Varsome BrowserGTF3C2
ACMGGTF3C2 variants
VarityQ8WUA4
Genomic Variants (DGV)GTF3C2 [DGVbeta]
DECIPHERGTF3C2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTF3C2 
Mutations
ICGC Data PortalGTF3C2 
TCGA Data PortalGTF3C2 
Broad Tumor PortalGTF3C2
OASIS PortalGTF3C2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF3C2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGTF3C2
Mutations and Diseases : HGMDGTF3C2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGTF3C2
DgiDB (Drug Gene Interaction Database)GTF3C2
DoCM (Curated mutations)GTF3C2
CIViC (Clinical Interpretations of Variants in Cancer)GTF3C2
Cancer3DGTF3C2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604883   
Orphanet
DisGeNETGTF3C2
MedgenGTF3C2
Genetic Testing Registry GTF3C2
NextProtQ8WUA4 [Medical]
GENETestsGTF3C2
Target ValidationGTF3C2
Huge Navigator GTF3C2 [HugePedia]
ClinGenGTF3C2
Clinical trials, drugs, therapy
MyCancerGenomeGTF3C2
Protein Interactions : CTDGTF3C2
Pharm GKB GenePA29053
PharosQ8WUA4
Clinical trialGTF3C2
Miscellaneous
canSAR (ICR)GTF3C2
HarmonizomeGTF3C2
DataMed IndexGTF3C2
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGTF3C2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:52:18 CEST 2021

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