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GTF3C2 (general transcription factor IIIC subunit 2)

Identity

Alias_namesgeneral transcription factor IIIC, polypeptide 2 (beta subunit, 110kD)
general transcription factor IIIC, polypeptide 2, beta 110kDa
Alias_symbol (synonym)KIAA0011
TFIIIC110
Other aliasTFIIIC-BETA
HGNC (Hugo) GTF3C2
LocusID (NCBI) 2976
Atlas_Id 64095
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 27325849 and ends at 27357034 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GTF3C2 (2p23.3) / GTF3C2 (2p23.3)GTF3C2 (2p23.3) / MPV17 (2p23.3)GTF3C2 (2p23.3) / WDR35 (2p24.1)
ITPR2 (12p12.1) / GTF3C2 (2p23.3)LOC100507412 (-) / GTF3C2 (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GTF3C2   4665
Cards
Entrez_Gene (NCBI)GTF3C2  2976  general transcription factor IIIC subunit 2
AliasesTFIIIC-BETA; TFIIIC110
GeneCards (Weizmann)GTF3C2
Ensembl hg19 (Hinxton)ENSG00000115207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115207 [Gene_View]  chr2:27325849-27357034 [Contig_View]  GTF3C2 [Vega]
ICGC DataPortalENSG00000115207
TCGA cBioPortalGTF3C2
AceView (NCBI)GTF3C2
Genatlas (Paris)GTF3C2
WikiGenes2976
SOURCE (Princeton)GTF3C2
Genetics Home Reference (NIH)GTF3C2
Genomic and cartography
GoldenPath hg38 (UCSC)GTF3C2  -     chr2:27325849-27357034 -  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF3C2  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblGTF3C2 - 2p23.3 [CytoView hg19]  GTF3C2 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBIGTF3C2 [Mapview hg19]  GTF3C2 [Mapview hg38]
OMIM604883   
Gene and transcription
Genbank (Entrez)AF054988 AK307656 BC000212 BC020981 BP249089
RefSeq transcript (Entrez)NM_001035521 NM_001318909 NM_001521
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTF3C2
Cluster EST : UnigeneHs.745168 [ NCBI ]
CGAP (NCI)Hs.745168
Alternative Splicing GalleryENSG00000115207
Gene ExpressionGTF3C2 [ NCBI-GEO ]   GTF3C2 [ EBI - ARRAY_EXPRESS ]   GTF3C2 [ SEEK ]   GTF3C2 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF3C2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2976
GTEX Portal (Tissue expression)GTF3C2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUA4
Splice isoforms : SwissVarQ8WUA4
PhosPhoSitePlusQ8WUA4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)GTF3C2
DMDM Disease mutations2976
Blocks (Seattle)GTF3C2
SuperfamilyQ8WUA4
Human Protein AtlasENSG00000115207
Peptide AtlasQ8WUA4
HPRD05347
IPIIPI00412837   IPI00878252   IPI00893663   IPI00893534   IPI00894465   IPI00894343   IPI00892857   IPI00894284   
Protein Interaction databases
DIP (DOE-UCLA)Q8WUA4
IntAct (EBI)Q8WUA4
FunCoupENSG00000115207
BioGRIDGTF3C2
STRING (EMBL)GTF3C2
ZODIACGTF3C2
Ontologies - Pathways
QuickGOQ8WUA4
Ontology : AmiGOtranscription factor TFIIIC complex  DNA binding  nucleoplasm  transcription, DNA-templated  transcription from RNA polymerase III promoter  5S class rRNA transcription from RNA polymerase III type 1 promoter  tRNA transcription from RNA polymerase III promoter  
Ontology : EGO-EBItranscription factor TFIIIC complex  DNA binding  nucleoplasm  transcription, DNA-templated  transcription from RNA polymerase III promoter  5S class rRNA transcription from RNA polymerase III type 1 promoter  tRNA transcription from RNA polymerase III promoter  
NDEx NetworkGTF3C2
Atlas of Cancer Signalling NetworkGTF3C2
Wikipedia pathwaysGTF3C2
Orthology - Evolution
OrthoDB2976
GeneTree (enSembl)ENSG00000115207
Phylogenetic Trees/Animal Genes : TreeFamGTF3C2
HOVERGENQ8WUA4
HOGENOMQ8WUA4
Homologs : HomoloGeneGTF3C2
Homology/Alignments : Family Browser (UCSC)GTF3C2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF3C2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF3C2
dbVarGTF3C2
ClinVarGTF3C2
1000_GenomesGTF3C2 
Exome Variant ServerGTF3C2
ExAC (Exome Aggregation Consortium)GTF3C2 (select the gene name)
Genetic variants : HAPMAP2976
Genomic Variants (DGV)GTF3C2 [DGVbeta]
DECIPHERGTF3C2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTF3C2 
Mutations
ICGC Data PortalGTF3C2 
TCGA Data PortalGTF3C2 
Broad Tumor PortalGTF3C2
OASIS PortalGTF3C2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF3C2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTF3C2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTF3C2
DgiDB (Drug Gene Interaction Database)GTF3C2
DoCM (Curated mutations)GTF3C2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTF3C2 (select a term)
intoGenGTF3C2
Cancer3DGTF3C2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604883   
Orphanet
MedgenGTF3C2
Genetic Testing Registry GTF3C2
NextProtQ8WUA4 [Medical]
TSGene2976
GENETestsGTF3C2
Target ValidationGTF3C2
Huge Navigator GTF3C2 [HugePedia]
snp3D : Map Gene to Disease2976
BioCentury BCIQGTF3C2
ClinGenGTF3C2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2976
Chemical/Pharm GKB GenePA29053
Clinical trialGTF3C2
Miscellaneous
canSAR (ICR)GTF3C2 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTF3C2
EVEXGTF3C2
GoPubMedGTF3C2
iHOPGTF3C2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:51:41 CEST 2017

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