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GTF3C4 (general transcription factor IIIC subunit 4)

Identity

Alias (NCBI)KAT12
TF3C-delta
TFIII90
TFIIIC290
TFIIIC90
TFIIICDELTA
HGNC (Hugo) GTF3C4
HGNC Alias symbTFIIIC90
KAT12
HGNC Previous namegeneral transcription factor IIIC, polypeptide 4 (90kD)
 general transcription factor IIIC, polypeptide 4, 90kDa
LocusID (NCBI) 9329
Atlas_Id 64098
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 132670464 and ends at 132694953 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ERCC6L2 (9q22.32) / GTF3C4 (9q34.13)GTF3C4 (9q34.13) / PSMC2 (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GTF3C4   4667
Cards
Entrez_Gene (NCBI)GTF3C4    general transcription factor IIIC subunit 4
AliasesKAT12; TF3C-delta; TFIII90; TFIIIC290; 
TFIIIC90; TFIIICDELTA
GeneCards (Weizmann)GTF3C4
Ensembl hg19 (Hinxton)ENSG00000125484 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125484 [Gene_View]  ENSG00000125484 [Sequence]  chr9:132670464-132694953 [Contig_View]  GTF3C4 [Vega]
ICGC DataPortalENSG00000125484
TCGA cBioPortalGTF3C4
AceView (NCBI)GTF3C4
Genatlas (Paris)GTF3C4
SOURCE (Princeton)GTF3C4
Genetics Home Reference (NIH)GTF3C4
Genomic and cartography
GoldenPath hg38 (UCSC)GTF3C4  -     chr9:132670464-132694953 +  9q34.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTF3C4  -     9q34.13   [Description]    (hg19-Feb_2009)
GoldenPathGTF3C4 - 9q34.13 [CytoView hg19]  GTF3C4 - 9q34.13 [CytoView hg38]
ImmunoBaseENSG00000125484
Genome Data Viewer NCBIGTF3C4 [Mapview hg19]  
OMIM604892   
Gene and transcription
Genbank (Entrez)AB072895 AF142328 AJ420430 AK024655 AK027509
RefSeq transcript (Entrez)NM_012204
Consensus coding sequences : CCDS (NCBI)GTF3C4
Gene ExpressionGTF3C4 [ NCBI-GEO ]   GTF3C4 [ EBI - ARRAY_EXPRESS ]   GTF3C4 [ SEEK ]   GTF3C4 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF3C4 [ Firebrowse - Broad ]
GenevisibleExpression of GTF3C4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9329
GTEX Portal (Tissue expression)GTF3C4
Human Protein AtlasENSG00000125484-GTF3C4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKN8
Catalytic activity : Enzyme2.3.1.48 [ Enzyme-Expasy ]   2.3.1.482.3.1.48 [ IntEnz-EBI ]   2.3.1.48 [ BRENDA ]   2.3.1.48 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9UKN8
Domains : Interpro (EBI)TFIIIC_delta_N    TFIIIC_Znf    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)TFIIIC_delta (PF12657)    zf-TFIIIC (PF12660)   
Domain families : Pfam (NCBI)pfam12657    pfam12660   
Conserved Domain (NCBI)GTF3C4
SuperfamilyQ9UKN8
AlphaFold pdb e-kbQ9UKN8   
Human Protein Atlas [tissue]ENSG00000125484-GTF3C4 [tissue]
HPRD11998
Protein Interaction databases
DIP (DOE-UCLA)Q9UKN8
IntAct (EBI)Q9UKN8
BioGRIDGTF3C4
STRING (EMBL)GTF3C4
ZODIACGTF3C4
Ontologies - Pathways
QuickGOQ9UKN8
Ontology : AmiGOtranscription factor TFIIIC complex  transcription factor TFIIIC complex  DNA binding  histone acetyltransferase activity  protein binding  nucleoplasm  nucleoplasm  mitochondrion  transcription by RNA polymerase III  transcription initiation from RNA polymerase III promoter  enzyme activator activity  histone acetylation  5S class rRNA transcription by RNA polymerase III  tRNA transcription by RNA polymerase III  
Ontology : EGO-EBItranscription factor TFIIIC complex  transcription factor TFIIIC complex  DNA binding  histone acetyltransferase activity  protein binding  nucleoplasm  nucleoplasm  mitochondrion  transcription by RNA polymerase III  transcription initiation from RNA polymerase III promoter  enzyme activator activity  histone acetylation  5S class rRNA transcription by RNA polymerase III  tRNA transcription by RNA polymerase III  
Pathways : BIOCARTARNA polymerase III transcription [Genes]   
NDEx NetworkGTF3C4
Atlas of Cancer Signalling NetworkGTF3C4
Wikipedia pathwaysGTF3C4
Orthology - Evolution
OrthoDB9329
GeneTree (enSembl)ENSG00000125484
Phylogenetic Trees/Animal Genes : TreeFamGTF3C4
Homologs : HomoloGeneGTF3C4
Homology/Alignments : Family Browser (UCSC)GTF3C4
Gene fusions - Rearrangements
Fusion : QuiverGTF3C4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF3C4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF3C4
dbVarGTF3C4
ClinVarGTF3C4
MonarchGTF3C4
1000_GenomesGTF3C4 
Exome Variant ServerGTF3C4
GNOMAD BrowserENSG00000125484
Varsome BrowserGTF3C4
ACMGGTF3C4 variants
VarityQ9UKN8
Genomic Variants (DGV)GTF3C4 [DGVbeta]
DECIPHERGTF3C4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTF3C4 
Mutations
ICGC Data PortalGTF3C4 
TCGA Data PortalGTF3C4 
Broad Tumor PortalGTF3C4
OASIS PortalGTF3C4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF3C4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGTF3C4
Mutations and Diseases : HGMDGTF3C4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGTF3C4
DgiDB (Drug Gene Interaction Database)GTF3C4
DoCM (Curated mutations)GTF3C4
CIViC (Clinical Interpretations of Variants in Cancer)GTF3C4
Cancer3DGTF3C4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604892   
Orphanet
DisGeNETGTF3C4
MedgenGTF3C4
Genetic Testing Registry GTF3C4
NextProtQ9UKN8 [Medical]
GENETestsGTF3C4
Target ValidationGTF3C4
Huge Navigator GTF3C4 [HugePedia]
ClinGenGTF3C4
Clinical trials, drugs, therapy
MyCancerGenomeGTF3C4
Protein Interactions : CTDGTF3C4
Pharm GKB GenePA29055
PharosQ9UKN8
Clinical trialGTF3C4
Miscellaneous
canSAR (ICR)GTF3C4
HarmonizomeGTF3C4
DataMed IndexGTF3C4
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGTF3C4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:52:19 CEST 2021

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