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GTF3C4 (general transcription factor IIIC, polypeptide 4, 90kDa)

Identity

Alias_namesgeneral transcription factor IIIC, polypeptide 4 (90kD)
general transcription factor IIIC, polypeptide 4, 90kDa
Alias_symbol (synonym)TFIIIC90
KAT12
Other aliasTFIII90
TFIIIC290
TFIIICDELTA
HGNC (Hugo) GTF3C4
LocusID (NCBI) 9329
Atlas_Id 64098
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 135545728 and ends at 135565470 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ERCC6L2 (9q22.32) / GTF3C4 (9q34.13)GTF3C4 (9q34.13) / PSMC2 (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GTF3C4   4667
Cards
Entrez_Gene (NCBI)GTF3C4  9329  general transcription factor IIIC, polypeptide 4, 90kDa
AliasesKAT12; TFIII90; TFIIIC290; TFIIIC90; 
TFIIICDELTA
GeneCards (Weizmann)GTF3C4
Ensembl hg19 (Hinxton) [Gene_View]  chr9:135545728-135565470 [Contig_View]  GTF3C4 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr9:135545728-135565470 [Contig_View]  GTF3C4 [Vega]
TCGA cBioPortalGTF3C4
AceView (NCBI)GTF3C4
Genatlas (Paris)GTF3C4
WikiGenes9329
SOURCE (Princeton)GTF3C4
Genetics Home Reference (NIH)GTF3C4
Genomic and cartography
GoldenPath hg19 (UCSC)GTF3C4  -     chr9:135545728-135565470 +  9q34.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GTF3C4  -     9q34.13   [Description]    (hg38-Dec_2013)
EnsemblGTF3C4 - 9q34.13 [CytoView hg19]  GTF3C4 - 9q34.13 [CytoView hg38]
Mapping of homologs : NCBIGTF3C4 [Mapview hg19]  GTF3C4 [Mapview hg38]
OMIM604892   
Gene and transcription
Genbank (Entrez)AF142328 AK024655 AK027509 BC011619 BC022787
RefSeq transcript (Entrez)NM_012204
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929367
Consensus coding sequences : CCDS (NCBI)GTF3C4
Cluster EST : UnigeneHs.656646 [ NCBI ]
CGAP (NCI)Hs.656646
Gene ExpressionGTF3C4 [ NCBI-GEO ]   GTF3C4 [ EBI - ARRAY_EXPRESS ]   GTF3C4 [ SEEK ]   GTF3C4 [ MEM ]
Gene Expression Viewer (FireBrowse)GTF3C4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9329
GTEX Portal (Tissue expression)GTF3C4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKN8
Splice isoforms : SwissVarQ9UKN8
Catalytic activity : Enzyme2.3.1.48 [ Enzyme-Expasy ]   2.3.1.482.3.1.48 [ IntEnz-EBI ]   2.3.1.48 [ BRENDA ]   2.3.1.48 [ KEGG ]   
PhosPhoSitePlusQ9UKN8
Domains : Interpro (EBI)TFIIIC_delta_N    TFIIIC_Znf    WD40_repeat_dom   
Domain families : Pfam (Sanger)TFIIIC_delta (PF12657)    zf-TFIIIC (PF12660)   
Domain families : Pfam (NCBI)pfam12657    pfam12660   
Conserved Domain (NCBI)GTF3C4
DMDM Disease mutations9329
Blocks (Seattle)GTF3C4
SuperfamilyQ9UKN8
Peptide AtlasQ9UKN8
HPRD11998
IPIIPI00016725   IPI00985202   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKN8
IntAct (EBI)Q9UKN8
BioGRIDGTF3C4
STRING (EMBL)GTF3C4
ZODIACGTF3C4
Ontologies - Pathways
QuickGOQ9UKN8
Ontology : AmiGOtranscription factor TFIIIC complex  DNA binding  histone acetyltransferase activity  protein binding  nucleoplasm  transcription, DNA-templated  transcription from RNA polymerase III promoter  transcription from RNA polymerase III promoter  transcription initiation from RNA polymerase III promoter  enzyme activator activity  gene expression  histone acetylation  histone acetylation  5S class rRNA transcription from RNA polymerase III type 1 promoter  tRNA transcription from RNA polymerase III promoter  positive regulation of catalytic activity  
Ontology : EGO-EBItranscription factor TFIIIC complex  DNA binding  histone acetyltransferase activity  protein binding  nucleoplasm  transcription, DNA-templated  transcription from RNA polymerase III promoter  transcription from RNA polymerase III promoter  transcription initiation from RNA polymerase III promoter  enzyme activator activity  gene expression  histone acetylation  histone acetylation  5S class rRNA transcription from RNA polymerase III type 1 promoter  tRNA transcription from RNA polymerase III promoter  positive regulation of catalytic activity  
Pathways : BIOCARTARNA polymerase III transcription [Genes]   
NDEx NetworkGTF3C4
Atlas of Cancer Signalling NetworkGTF3C4
Wikipedia pathwaysGTF3C4
Orthology - Evolution
OrthoDB9329
Phylogenetic Trees/Animal Genes : TreeFamGTF3C4
HOVERGENQ9UKN8
HOGENOMQ9UKN8
Homologs : HomoloGeneGTF3C4
Homology/Alignments : Family Browser (UCSC)GTF3C4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTF3C4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTF3C4
dbVarGTF3C4
ClinVarGTF3C4
1000_GenomesGTF3C4 
Exome Variant ServerGTF3C4
ExAC (Exome Aggregation Consortium)GTF3C4 (select the gene name)
Genetic variants : HAPMAP9329
Genomic Variants (DGV)GTF3C4 [DGVbeta]
DECIPHER (Syndromes)9:135545728-135565470  
CONAN: Copy Number AnalysisGTF3C4 
Mutations
ICGC Data PortalGTF3C4 
TCGA Data PortalGTF3C4 
Broad Tumor PortalGTF3C4
OASIS PortalGTF3C4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTF3C4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTF3C4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTF3C4
DgiDB (Drug Gene Interaction Database)GTF3C4
DoCM (Curated mutations)GTF3C4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTF3C4 (select a term)
intoGenGTF3C4
Cancer3DGTF3C4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604892   
Orphanet
MedgenGTF3C4
Genetic Testing Registry GTF3C4
NextProtQ9UKN8 [Medical]
TSGene9329
GENETestsGTF3C4
Huge Navigator GTF3C4 [HugePedia]
snp3D : Map Gene to Disease9329
BioCentury BCIQGTF3C4
ClinGenGTF3C4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9329
Chemical/Pharm GKB GenePA29055
Clinical trialGTF3C4
Miscellaneous
canSAR (ICR)GTF3C4 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTF3C4
EVEXGTF3C4
GoPubMedGTF3C4
iHOPGTF3C4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:07:09 CET 2017

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