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GTPBP1 (GTP binding protein 1)

Identity

Alias (NCBI)GP-1
GP1
HSPC018
HGNC (Hugo) GTPBP1
HGNC Alias symbGP-1
HSPC018
LocusID (NCBI) 9567
Atlas_Id 64101
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 38705944 and ends at 38733587 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GTPBP1 (22q13.1) / GTPBP1 (22q13.1)GTPBP1 (22q13.1) / TAF1D (11q21)GTPBP1 (22q13.1) / TOMM22 (22q13.1)
HLA-E (6p21.33) / GTPBP1 (22q13.1)HMGCLL1 (6p12.1) / GTPBP1 (22q13.1)REPS1 (6q24.1) / GTPBP1 (22q13.1)
SFXN5 (2p13.2) / GTPBP1 (22q13.1)ZMYND8 (20q13.12) / GTPBP1 (22q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GTPBP1   4669
Cards
Entrez_Gene (NCBI)GTPBP1    GTP binding protein 1
AliasesGP-1; GP1; HSPC018
GeneCards (Weizmann)GTPBP1
Ensembl hg19 (Hinxton)ENSG00000100226 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100226 [Gene_View]  ENSG00000100226 [Sequence]  chr22:38705944-38733587 [Contig_View]  GTPBP1 [Vega]
ICGC DataPortalENSG00000100226
TCGA cBioPortalGTPBP1
AceView (NCBI)GTPBP1
Genatlas (Paris)GTPBP1
SOURCE (Princeton)GTPBP1
Genetics Home Reference (NIH)GTPBP1
Genomic and cartography
GoldenPath hg38 (UCSC)GTPBP1  -     chr22:38705944-38733587 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTPBP1  -     22q13.1   [Description]    (hg19-Feb_2009)
GoldenPathGTPBP1 - 22q13.1 [CytoView hg19]  GTPBP1 - 22q13.1 [CytoView hg38]
ImmunoBaseENSG00000100226
Genome Data Viewer NCBIGTPBP1 [Mapview hg19]  
OMIM602245   
Gene and transcription
Genbank (Entrez)AF077204 AF370385 AI570660 AK095950 AK096647
RefSeq transcript (Entrez)NM_004286
Consensus coding sequences : CCDS (NCBI)GTPBP1
Gene ExpressionGTPBP1 [ NCBI-GEO ]   GTPBP1 [ EBI - ARRAY_EXPRESS ]   GTPBP1 [ SEEK ]   GTPBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)GTPBP1 [ Firebrowse - Broad ]
GenevisibleExpression of GTPBP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9567
GTEX Portal (Tissue expression)GTPBP1
Human Protein AtlasENSG00000100226-GTPBP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00178   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00178  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00178
PhosPhoSitePlusO00178
Domaine pattern : Prosite (Expaxy)G_TR_2 (PS51722)   
Domains : Interpro (EBI)GTPB1    GTPBP1-like    P-loop_NTPase    T_Tr_GTP-bd_dom    Transl_B-barrel_sf    Transl_elong_EF1A/Init_IF2_C   
Domain families : Pfam (Sanger)GTP_EFTU (PF00009)   
Domain families : Pfam (NCBI)pfam00009   
Conserved Domain (NCBI)GTPBP1
SuperfamilyO00178
AlphaFold pdb e-kbO00178   
Human Protein Atlas [tissue]ENSG00000100226-GTPBP1 [tissue]
HPRD03765
Protein Interaction databases
DIP (DOE-UCLA)O00178
IntAct (EBI)O00178
BioGRIDGTPBP1
STRING (EMBL)GTPBP1
ZODIACGTPBP1
Ontologies - Pathways
QuickGOO00178
Ontology : AmiGOcytoplasmic exosome (RNase complex)  RNA binding  translation elongation factor activity  GTPase activity  protein binding  GTP binding  cytosol  translational elongation  immune response  signal transduction  membrane  GTP metabolic process  positive regulation of mRNA catabolic process  
Ontology : EGO-EBIcytoplasmic exosome (RNase complex)  RNA binding  translation elongation factor activity  GTPase activity  protein binding  GTP binding  cytosol  translational elongation  immune response  signal transduction  membrane  GTP metabolic process  positive regulation of mRNA catabolic process  
NDEx NetworkGTPBP1
Atlas of Cancer Signalling NetworkGTPBP1
Wikipedia pathwaysGTPBP1
Orthology - Evolution
OrthoDB9567
GeneTree (enSembl)ENSG00000100226
Phylogenetic Trees/Animal Genes : TreeFamGTPBP1
Homologs : HomoloGeneGTPBP1
Homology/Alignments : Family Browser (UCSC)GTPBP1
Gene fusions - Rearrangements
Fusion : QuiverGTPBP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTPBP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTPBP1
dbVarGTPBP1
ClinVarGTPBP1
MonarchGTPBP1
1000_GenomesGTPBP1 
Exome Variant ServerGTPBP1
GNOMAD BrowserENSG00000100226
Varsome BrowserGTPBP1
ACMGGTPBP1 variants
VarityO00178
Genomic Variants (DGV)GTPBP1 [DGVbeta]
DECIPHERGTPBP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTPBP1 
Mutations
ICGC Data PortalGTPBP1 
TCGA Data PortalGTPBP1 
Broad Tumor PortalGTPBP1
OASIS PortalGTPBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTPBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGTPBP1
Mutations and Diseases : HGMDGTPBP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGTPBP1
DgiDB (Drug Gene Interaction Database)GTPBP1
DoCM (Curated mutations)GTPBP1
CIViC (Clinical Interpretations of Variants in Cancer)GTPBP1
Cancer3DGTPBP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602245   
Orphanet
DisGeNETGTPBP1
MedgenGTPBP1
Genetic Testing Registry GTPBP1
NextProtO00178 [Medical]
GENETestsGTPBP1
Target ValidationGTPBP1
Huge Navigator GTPBP1 [HugePedia]
ClinGenGTPBP1
Clinical trials, drugs, therapy
MyCancerGenomeGTPBP1
Protein Interactions : CTDGTPBP1
Pharm GKB GenePA29057
PharosO00178
Clinical trialGTPBP1
Miscellaneous
canSAR (ICR)GTPBP1
HarmonizomeGTPBP1
DataMed IndexGTPBP1
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGTPBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:52:19 CEST 2021

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