Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GTPBP1 (GTP binding protein 1)

Identity

Alias_symbol (synonym)GP-1
HSPC018
Other aliasGP1
HGNC (Hugo) GTPBP1
LocusID (NCBI) 9567
Atlas_Id 64101
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 39101807 and ends at 39129592 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GTPBP1 (22q13.1) / GTPBP1 (22q13.1)GTPBP1 (22q13.1) / TAF1D (11q21)GTPBP1 (22q13.1) / TOMM22 (22q13.1)
HLA-E (6p21.33) / GTPBP1 (22q13.1)HMGCLL1 (6p12.1) / GTPBP1 (22q13.1)REPS1 (6q24.1) / GTPBP1 (22q13.1)
SFXN5 (2p13.2) / GTPBP1 (22q13.1)ZMYND8 (20q13.12) / GTPBP1 (22q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GTPBP1   4669
Cards
Entrez_Gene (NCBI)GTPBP1  9567  GTP binding protein 1
AliasesGP-1; GP1; HSPC018
GeneCards (Weizmann)GTPBP1
Ensembl hg19 (Hinxton)ENSG00000100226 [Gene_View]  chr22:39101807-39129592 [Contig_View]  GTPBP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100226 [Gene_View]  chr22:39101807-39129592 [Contig_View]  GTPBP1 [Vega]
ICGC DataPortalENSG00000100226
TCGA cBioPortalGTPBP1
AceView (NCBI)GTPBP1
Genatlas (Paris)GTPBP1
WikiGenes9567
SOURCE (Princeton)GTPBP1
Genetics Home Reference (NIH)GTPBP1
Genomic and cartography
GoldenPath hg19 (UCSC)GTPBP1  -     chr22:39101807-39129592 +  22q13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GTPBP1  -     22q13.1   [Description]    (hg38-Dec_2013)
EnsemblGTPBP1 - 22q13.1 [CytoView hg19]  GTPBP1 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIGTPBP1 [Mapview hg19]  GTPBP1 [Mapview hg38]
OMIM602245   
Gene and transcription
Genbank (Entrez)AF077204 AF370385 AI570660 AK095950 AK096647
RefSeq transcript (Entrez)NM_004286
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)GTPBP1
Cluster EST : UnigeneHs.276925 [ NCBI ]
CGAP (NCI)Hs.276925
Alternative Splicing GalleryENSG00000100226
Gene ExpressionGTPBP1 [ NCBI-GEO ]   GTPBP1 [ EBI - ARRAY_EXPRESS ]   GTPBP1 [ SEEK ]   GTPBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)GTPBP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9567
GTEX Portal (Tissue expression)GTPBP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00178   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00178  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00178
Splice isoforms : SwissVarO00178
PhosPhoSitePlusO00178
Domaine pattern : Prosite (Expaxy)G_TR_2 (PS51722)   
Domains : Interpro (EBI)EF_GTP-bd_dom    P-loop_NTPase    Transl_B-barrel    Transl_elong_EF1A/Init_IF2_C    Transl_elong_EFTu/EF1A_2    Transl_elong_EFTu/EF1A_C   
Domain families : Pfam (Sanger)GTP_EFTU (PF00009)    GTP_EFTU_D2 (PF03144)    GTP_EFTU_D3 (PF03143)   
Domain families : Pfam (NCBI)pfam00009    pfam03144    pfam03143   
Conserved Domain (NCBI)GTPBP1
DMDM Disease mutations9567
Blocks (Seattle)GTPBP1
SuperfamilyO00178
Human Protein AtlasENSG00000100226
Peptide AtlasO00178
HPRD03765
IPIIPI00010463   IPI00878100   IPI00435959   IPI00022287   IPI00879901   IPI01010604   IPI01010966   IPI01011444   IPI01011840   IPI01012230   IPI01013085   
Protein Interaction databases
DIP (DOE-UCLA)O00178
IntAct (EBI)O00178
FunCoupENSG00000100226
BioGRIDGTPBP1
STRING (EMBL)GTPBP1
ZODIACGTPBP1
Ontologies - Pathways
QuickGOO00178
Ontology : AmiGOcytoplasmic exosome (RNase complex)  GTPase activity  GTP binding  cytosol  immune response  signal transduction  metabolic process  metabolic process  membrane  poly(A) RNA binding  positive regulation of mRNA catabolic process  
Ontology : EGO-EBIcytoplasmic exosome (RNase complex)  GTPase activity  GTP binding  cytosol  immune response  signal transduction  metabolic process  metabolic process  membrane  poly(A) RNA binding  positive regulation of mRNA catabolic process  
NDEx NetworkGTPBP1
Atlas of Cancer Signalling NetworkGTPBP1
Wikipedia pathwaysGTPBP1
Orthology - Evolution
OrthoDB9567
GeneTree (enSembl)ENSG00000100226
Phylogenetic Trees/Animal Genes : TreeFamGTPBP1
HOVERGENO00178
HOGENOMO00178
Homologs : HomoloGeneGTPBP1
Homology/Alignments : Family Browser (UCSC)GTPBP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTPBP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTPBP1
dbVarGTPBP1
ClinVarGTPBP1
1000_GenomesGTPBP1 
Exome Variant ServerGTPBP1
ExAC (Exome Aggregation Consortium)GTPBP1 (select the gene name)
Genetic variants : HAPMAP9567
Genomic Variants (DGV)GTPBP1 [DGVbeta]
DECIPHER (Syndromes)22:39101807-39129592  ENSG00000100226
CONAN: Copy Number AnalysisGTPBP1 
Mutations
ICGC Data PortalGTPBP1 
TCGA Data PortalGTPBP1 
Broad Tumor PortalGTPBP1
OASIS PortalGTPBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTPBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTPBP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTPBP1
DgiDB (Drug Gene Interaction Database)GTPBP1
DoCM (Curated mutations)GTPBP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTPBP1 (select a term)
intoGenGTPBP1
Cancer3DGTPBP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602245   
Orphanet
MedgenGTPBP1
Genetic Testing Registry GTPBP1
NextProtO00178 [Medical]
TSGene9567
GENETestsGTPBP1
Huge Navigator GTPBP1 [HugePedia]
snp3D : Map Gene to Disease9567
BioCentury BCIQGTPBP1
ClinGenGTPBP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9567
Chemical/Pharm GKB GenePA29057
Clinical trialGTPBP1
Miscellaneous
canSAR (ICR)GTPBP1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTPBP1
EVEXGTPBP1
GoPubMedGTPBP1
iHOPGTPBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:07:10 CET 2017

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