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GTPBP10 (GTP binding protein 10)

Identity

Alias_namesGTP-binding protein 10 (putative)
Alias_symbol (synonym)DKFZP686A10121
FLJ38242
OBGH2
Other aliasObgH2
UG0751c10
HGNC (Hugo) GTPBP10
LocusID (NCBI) 85865
Atlas_Id 64102
Location 7q21.13  [Link to chromosome band 7q21]
Location_base_pair Starts at 90346665 and ends at 90391455 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GTPBP10 (7q21.13) / PDS5B (13q13.1)SDHA (5p15.33) / GTPBP10 (7q21.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(2;7)(q35;q21) GTPBP10/BARD1
t(2;7)(q35;q21) GTPBP10/BARD1

External links

Nomenclature
HGNC (Hugo)GTPBP10   25106
Cards
Entrez_Gene (NCBI)GTPBP10  85865  GTP binding protein 10
AliasesObgH2; UG0751c10
GeneCards (Weizmann)GTPBP10
Ensembl hg19 (Hinxton)ENSG00000105793 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105793 [Gene_View]  ENSG00000105793 [Sequence]  chr7:90346665-90391455 [Contig_View]  GTPBP10 [Vega]
ICGC DataPortalENSG00000105793
TCGA cBioPortalGTPBP10
AceView (NCBI)GTPBP10
Genatlas (Paris)GTPBP10
WikiGenes85865
SOURCE (Princeton)GTPBP10
Genetics Home Reference (NIH)GTPBP10
Genomic and cartography
GoldenPath hg38 (UCSC)GTPBP10  -     chr7:90346665-90391455 +  7q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTPBP10  -     7q21.13   [Description]    (hg19-Feb_2009)
GoldenPathGTPBP10 - 7q21.13 [CytoView hg19]  GTPBP10 - 7q21.13 [CytoView hg38]
ImmunoBaseENSG00000105793
Mapping of homologs : NCBIGTPBP10 [Mapview hg19]  GTPBP10 [Mapview hg38]
OMIM610920   
Gene and transcription
Genbank (Entrez)AF351613 AK093649 AK095561 AK125553 AK294325
RefSeq transcript (Entrez)NM_001042717 NM_033107
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTPBP10
Alternative Splicing GalleryENSG00000105793
Gene ExpressionGTPBP10 [ NCBI-GEO ]   GTPBP10 [ EBI - ARRAY_EXPRESS ]   GTPBP10 [ SEEK ]   GTPBP10 [ MEM ]
Gene Expression Viewer (FireBrowse)GTPBP10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85865
GTEX Portal (Tissue expression)GTPBP10
Human Protein AtlasENSG00000105793-GTPBP10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA4D1E9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA4D1E9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA4D1E9
Splice isoforms : SwissVarA4D1E9
PhosPhoSitePlusA4D1E9
Domaine pattern : Prosite (Expaxy)G_OBG (PS51710)    OBG (PS51883)   
Domains : Interpro (EBI)G_OBG    GTP-bd_Obg    GTP1_OBG_dom    GTP1_OBG_dom_sf    GTP_binding_domain    P-loop_NTPase   
Domain families : Pfam (Sanger)GTP1_OBG (PF01018)    MMR_HSR1 (PF01926)   
Domain families : Pfam (NCBI)pfam01018    pfam01926   
Conserved Domain (NCBI)GTPBP10
DMDM Disease mutations85865
Blocks (Seattle)GTPBP10
SuperfamilyA4D1E9
Human Protein Atlas [tissue]ENSG00000105793-GTPBP10 [tissue]
Peptide AtlasA4D1E9
HPRD14262
IPIIPI00167638   IPI00217526   IPI00552355   IPI00792449   IPI00791894   IPI00879953   IPI01012497   IPI00878942   IPI00926915   
Protein Interaction databases
DIP (DOE-UCLA)A4D1E9
IntAct (EBI)A4D1E9
FunCoupENSG00000105793
BioGRIDGTPBP10
STRING (EMBL)GTPBP10
ZODIACGTPBP10
Ontologies - Pathways
QuickGOA4D1E9
Ontology : AmiGORNA binding  protein binding  GTP binding  chromosome  nucleolus  ribosome biogenesis  
Ontology : EGO-EBIRNA binding  protein binding  GTP binding  chromosome  nucleolus  ribosome biogenesis  
NDEx NetworkGTPBP10
Atlas of Cancer Signalling NetworkGTPBP10
Wikipedia pathwaysGTPBP10
Orthology - Evolution
OrthoDB85865
GeneTree (enSembl)ENSG00000105793
Phylogenetic Trees/Animal Genes : TreeFamGTPBP10
HOGENOMA4D1E9
Homologs : HomoloGeneGTPBP10
Homology/Alignments : Family Browser (UCSC)GTPBP10
Gene fusions - Rearrangements
Fusion : QuiverGTPBP10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTPBP10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTPBP10
dbVarGTPBP10
ClinVarGTPBP10
1000_GenomesGTPBP10 
Exome Variant ServerGTPBP10
ExAC (Exome Aggregation Consortium)ENSG00000105793
GNOMAD BrowserENSG00000105793
Varsome BrowserGTPBP10
Genetic variants : HAPMAP85865
Genomic Variants (DGV)GTPBP10 [DGVbeta]
DECIPHERGTPBP10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTPBP10 
Mutations
ICGC Data PortalGTPBP10 
TCGA Data PortalGTPBP10 
Broad Tumor PortalGTPBP10
OASIS PortalGTPBP10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTPBP10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGTPBP10
Mutations and Diseases : HGMDGTPBP10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTPBP10
DgiDB (Drug Gene Interaction Database)GTPBP10
DoCM (Curated mutations)GTPBP10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTPBP10 (select a term)
intoGenGTPBP10
Cancer3DGTPBP10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610920   
Orphanet
DisGeNETGTPBP10
MedgenGTPBP10
Genetic Testing Registry GTPBP10
NextProtA4D1E9 [Medical]
TSGene85865
GENETestsGTPBP10
Target ValidationGTPBP10
Huge Navigator GTPBP10 [HugePedia]
snp3D : Map Gene to Disease85865
BioCentury BCIQGTPBP10
ClinGenGTPBP10
Clinical trials, drugs, therapy
Protein Interactions : CTD85865
Pharm GKB GenePA162390482
Clinical trialGTPBP10
Miscellaneous
canSAR (ICR)GTPBP10 (select the gene name)
HarmonizomeGTPBP10
DataMed IndexGTPBP10
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTPBP10
EVEXGTPBP10
GoPubMedGTPBP10
iHOPGTPBP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Jun 30 19:41:36 CEST 2020
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