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GTPBP2 (GTP binding protein 2)

Identity

Other alias-
HGNC (Hugo) GTPBP2
LocusID (NCBI) 54676
Atlas_Id 64103
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 43620481 and ends at 43627353 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GTPBP2 (6p21.1) / GTPBP2 (6p21.1)GTPBP2 (6p21.1) / HIST1H2BJ (6p22.1)SMAGP (12q13.13) / GTPBP2 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;p22) GTPBP2/HIST1H2BJ


External links

Nomenclature
HGNC (Hugo)GTPBP2   4670
Cards
Entrez_Gene (NCBI)GTPBP2  54676  GTP binding protein 2
Aliases
GeneCards (Weizmann)GTPBP2
Ensembl hg19 (Hinxton)ENSG00000172432 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172432 [Gene_View]  ENSG00000172432 [Sequence]  chr6:43620481-43627353 [Contig_View]  GTPBP2 [Vega]
ICGC DataPortalENSG00000172432
TCGA cBioPortalGTPBP2
AceView (NCBI)GTPBP2
Genatlas (Paris)GTPBP2
WikiGenes54676
SOURCE (Princeton)GTPBP2
Genetics Home Reference (NIH)GTPBP2
Genomic and cartography
GoldenPath hg38 (UCSC)GTPBP2  -     chr6:43620481-43627353 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTPBP2  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblGTPBP2 - 6p21.1 [CytoView hg19]  GTPBP2 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIGTPBP2 [Mapview hg19]  GTPBP2 [Mapview hg38]
OMIM607434   
Gene and transcription
Genbank (Entrez)AB024574 AF168990 AJ420518 AK000430 AK290267
RefSeq transcript (Entrez)NM_001286216 NM_019096
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTPBP2
Cluster EST : UnigeneHs.485449 [ NCBI ]
CGAP (NCI)Hs.485449
Alternative Splicing GalleryENSG00000172432
Gene ExpressionGTPBP2 [ NCBI-GEO ]   GTPBP2 [ EBI - ARRAY_EXPRESS ]   GTPBP2 [ SEEK ]   GTPBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)GTPBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54676
GTEX Portal (Tissue expression)GTPBP2
Human Protein AtlasENSG00000172432-GTPBP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BX10   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BX10  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BX10
Splice isoforms : SwissVarQ9BX10
PhosPhoSitePlusQ9BX10
Domaine pattern : Prosite (Expaxy)G_TR_2 (PS51722)   
Domains : Interpro (EBI)P-loop_NTPase    TF_GTP-bd_dom    Transl_B-barrel    Transl_elong_EF1A/Init_IF2_C   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GTPBP2
DMDM Disease mutations54676
Blocks (Seattle)GTPBP2
SuperfamilyQ9BX10
Human Protein Atlas [tissue]ENSG00000172432-GTPBP2 [tissue]
Peptide AtlasQ9BX10
HPRD08465
IPIIPI00151360   IPI00785134   IPI00784918   IPI00643323   IPI00514987   IPI00514440   IPI00383371   IPI00032534   IPI00515024   
Protein Interaction databases
DIP (DOE-UCLA)Q9BX10
IntAct (EBI)Q9BX10
FunCoupENSG00000172432
BioGRIDGTPBP2
STRING (EMBL)GTPBP2
ZODIACGTPBP2
Ontologies - Pathways
QuickGOQ9BX10
Ontology : AmiGOplatelet degranulation  GTPase activity  protein binding  GTP binding  extracellular region  biological_process  platelet alpha granule lumen  intracellular membrane-bounded organelle  
Ontology : EGO-EBIplatelet degranulation  GTPase activity  protein binding  GTP binding  extracellular region  biological_process  platelet alpha granule lumen  intracellular membrane-bounded organelle  
NDEx NetworkGTPBP2
Atlas of Cancer Signalling NetworkGTPBP2
Wikipedia pathwaysGTPBP2
Orthology - Evolution
OrthoDB54676
GeneTree (enSembl)ENSG00000172432
Phylogenetic Trees/Animal Genes : TreeFamGTPBP2
HOVERGENQ9BX10
HOGENOMQ9BX10
Homologs : HomoloGeneGTPBP2
Homology/Alignments : Family Browser (UCSC)GTPBP2
Gene fusions - Rearrangements
Fusion : QuiverGTPBP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTPBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTPBP2
dbVarGTPBP2
ClinVarGTPBP2
1000_GenomesGTPBP2 
Exome Variant ServerGTPBP2
ExAC (Exome Aggregation Consortium)ENSG00000172432
GNOMAD BrowserENSG00000172432
Varsome BrowserGTPBP2
Genetic variants : HAPMAP54676
Genomic Variants (DGV)GTPBP2 [DGVbeta]
DECIPHERGTPBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTPBP2 
Mutations
ICGC Data PortalGTPBP2 
TCGA Data PortalGTPBP2 
Broad Tumor PortalGTPBP2
OASIS PortalGTPBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTPBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTPBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTPBP2
DgiDB (Drug Gene Interaction Database)GTPBP2
DoCM (Curated mutations)GTPBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTPBP2 (select a term)
intoGenGTPBP2
Cancer3DGTPBP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607434   
Orphanet
DisGeNETGTPBP2
MedgenGTPBP2
Genetic Testing Registry GTPBP2
NextProtQ9BX10 [Medical]
TSGene54676
GENETestsGTPBP2
Target ValidationGTPBP2
Huge Navigator GTPBP2 [HugePedia]
snp3D : Map Gene to Disease54676
BioCentury BCIQGTPBP2
ClinGenGTPBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54676
Chemical/Pharm GKB GenePA29058
Clinical trialGTPBP2
Miscellaneous
canSAR (ICR)GTPBP2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTPBP2
EVEXGTPBP2
GoPubMedGTPBP2
iHOPGTPBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:48:18 CEST 2018

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