Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GTPBP4 (GTP binding protein 4)

Identity

Alias_symbol (synonym)CRFG
NGB
FLJ10690
FLJ10686
NOG1
Other alias
HGNC (Hugo) GTPBP4
LocusID (NCBI) 23560
Atlas_Id 47627
Location 10p15.3  [Link to chromosome band 10p15]
Location_base_pair Starts at 988409 and ends at 1017768 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		ANP32B (9q22.33) / GTPBP4 (10p15.3)ARHGAP8 (22q13.31) / GTPBP4 (10p15.3)GTPBP4 (10p15.3) / NIN (14q22.1)
MED13L (12q24.21) / GTPBP4 (10p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GTPBP4   21535
Cards
Entrez_Gene (NCBI)GTPBP4  23560  GTP binding protein 4
AliasesCRFG; NGB; NOG1
GeneCards (Weizmann)GTPBP4
Ensembl hg19 (Hinxton)ENSG00000107937 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107937 [Gene_View]  chr10:988409-1017768 [Contig_View]  GTPBP4 [Vega]
ICGC DataPortalENSG00000107937
TCGA cBioPortalGTPBP4
AceView (NCBI)GTPBP4
Genatlas (Paris)GTPBP4
WikiGenes23560
SOURCE (Princeton)GTPBP4
Genetics Home Reference (NIH)GTPBP4
Genomic and cartography
GoldenPath hg38 (UCSC)GTPBP4  -     chr10:988409-1017768 +  10p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GTPBP4  -     10p15.3   [Description]    (hg19-Feb_2009)
EnsemblGTPBP4 - 10p15.3 [CytoView hg19]  GTPBP4 - 10p15.3 [CytoView hg38]
Mapping of homologs : NCBIGTPBP4 [Mapview hg19]  GTPBP4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF120334 AF325353 AI740474 AK001548 AK001552
RefSeq transcript (Entrez)NM_012341
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GTPBP4
Cluster EST : UnigeneHs.215766 [ NCBI ]
CGAP (NCI)Hs.215766
Alternative Splicing GalleryENSG00000107937
Gene ExpressionGTPBP4 [ NCBI-GEO ]   GTPBP4 [ EBI - ARRAY_EXPRESS ]   GTPBP4 [ SEEK ]   GTPBP4 [ MEM ]
Gene Expression Viewer (FireBrowse)GTPBP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23560
GTEX Portal (Tissue expression)GTPBP4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZE4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZE4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZE4
Splice isoforms : SwissVarQ9BZE4
PhosPhoSitePlusQ9BZE4
Domaine pattern : Prosite (Expaxy)G_OBG (PS51710)   
Domains : Interpro (EBI)G_OBG    GTP_binding_domain    NOG1    NOG1_Rossman_fold_dom    NOG_C    P-loop_NTPase    Small_GTP-bd_dom   
Domain families : Pfam (Sanger)NOG1 (PF06858)    NOGCT (PF08155)   
Domain families : Pfam (NCBI)pfam06858    pfam08155   
Conserved Domain (NCBI)GTPBP4
DMDM Disease mutations23560
Blocks (Seattle)GTPBP4
SuperfamilyQ9BZE4
Human Protein AtlasENSG00000107937
Peptide AtlasQ9BZE4
HPRD09976
IPIIPI00385042   IPI01014195   IPI00645138   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZE4
IntAct (EBI)Q9BZE4
FunCoupENSG00000107937
BioGRIDGTPBP4
STRING (EMBL)GTPBP4
ZODIACGTPBP4
Ontologies - Pathways
QuickGOQ9BZE4
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  osteoblast differentiation  RNA binding  GTPase activity  protein binding  GTP binding  nucleus  nucleolus  cytoplasm  Golgi apparatus  cytosol  negative regulation of DNA replication  negative regulation of cell proliferation  membrane  negative regulation of cell-cell adhesion  negative regulation of cell migration  negative regulation of protein ubiquitination  nuclear membrane  negative regulation of collagen binding  perinuclear region of cytoplasm  protein stabilization  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  osteoblast differentiation  RNA binding  GTPase activity  protein binding  GTP binding  nucleus  nucleolus  cytoplasm  Golgi apparatus  cytosol  negative regulation of DNA replication  negative regulation of cell proliferation  membrane  negative regulation of cell-cell adhesion  negative regulation of cell migration  negative regulation of protein ubiquitination  nuclear membrane  negative regulation of collagen binding  perinuclear region of cytoplasm  protein stabilization  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkGTPBP4
Atlas of Cancer Signalling NetworkGTPBP4
Wikipedia pathwaysGTPBP4
Orthology - Evolution
OrthoDB23560
GeneTree (enSembl)ENSG00000107937
Phylogenetic Trees/Animal Genes : TreeFamGTPBP4
HOVERGENQ9BZE4
HOGENOMQ9BZE4
Homologs : HomoloGeneGTPBP4
Homology/Alignments : Family Browser (UCSC)GTPBP4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGTPBP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GTPBP4
dbVarGTPBP4
ClinVarGTPBP4
1000_GenomesGTPBP4 
Exome Variant ServerGTPBP4
ExAC (Exome Aggregation Consortium)GTPBP4 (select the gene name)
Genetic variants : HAPMAP23560
Genomic Variants (DGV)GTPBP4 [DGVbeta]
DECIPHERGTPBP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGTPBP4 
Mutations
ICGC Data PortalGTPBP4 
TCGA Data PortalGTPBP4 
Broad Tumor PortalGTPBP4
OASIS PortalGTPBP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGTPBP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGTPBP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GTPBP4
DgiDB (Drug Gene Interaction Database)GTPBP4
DoCM (Curated mutations)GTPBP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GTPBP4 (select a term)
intoGenGTPBP4
Cancer3DGTPBP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenGTPBP4
Genetic Testing Registry GTPBP4
NextProtQ9BZE4 [Medical]
TSGene23560
GENETestsGTPBP4
Target ValidationGTPBP4
Huge Navigator GTPBP4 [HugePedia]
snp3D : Map Gene to Disease23560
BioCentury BCIQGTPBP4
ClinGenGTPBP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23560
Chemical/Pharm GKB GenePA134922009
Clinical trialGTPBP4
Miscellaneous
canSAR (ICR)GTPBP4 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGTPBP4
EVEXGTPBP4
GoPubMedGTPBP4
iHOPGTPBP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:54:55 CEST 2017
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