Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GUCA1A (guanylate cyclase activator 1A)

Identity

Alias_namesGUCA
GUCA1
C6orf131
chromosome 6 open reading frame 131
guanylate cyclase activator 1A (retina)
Alias_symbol (synonym)GCAP
GCAP1
COD3
dJ139D8.6
CORD14
Other alias
HGNC (Hugo) GUCA1A
LocusID (NCBI) 2978
Atlas_Id 64111
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 42155377 and ends at 42180083 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GUCA1A   4678
Cards
Entrez_Gene (NCBI)GUCA1A  2978  guanylate cyclase activator 1A
AliasesC6orf131; COD3; CORD14; GCAP; 
GCAP1; GUCA; GUCA1
GeneCards (Weizmann)GUCA1A
Ensembl hg19 (Hinxton)ENSG00000048545 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000048545 [Gene_View]  ENSG00000048545 [Sequence]  chr6:42155377-42180083 [Contig_View]  GUCA1A [Vega]
ICGC DataPortalENSG00000048545
TCGA cBioPortalGUCA1A
AceView (NCBI)GUCA1A
Genatlas (Paris)GUCA1A
WikiGenes2978
SOURCE (Princeton)GUCA1A
Genetics Home Reference (NIH)GUCA1A
Genomic and cartography
GoldenPath hg38 (UCSC)GUCA1A  -     chr6:42155377-42180083 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GUCA1A  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblGUCA1A - 6p21.1 [CytoView hg19]  GUCA1A - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIGUCA1A [Mapview hg19]  GUCA1A [Mapview hg38]
OMIM600364   602093   
Gene and transcription
Genbank (Entrez)AA400590 AK125780 AK313865 BC031663 BM717123
RefSeq transcript (Entrez)NM_000409 NM_001319061 NM_001319062
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GUCA1A
Cluster EST : UnigeneHs.92858 [ NCBI ]
CGAP (NCI)Hs.92858
Alternative Splicing GalleryENSG00000048545
Gene ExpressionGUCA1A [ NCBI-GEO ]   GUCA1A [ EBI - ARRAY_EXPRESS ]   GUCA1A [ SEEK ]   GUCA1A [ MEM ]
Gene Expression Viewer (FireBrowse)GUCA1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2978
GTEX Portal (Tissue expression)GUCA1A
Human Protein AtlasENSG00000048545-GUCA1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43080   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43080  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43080
Splice isoforms : SwissVarP43080
PhosPhoSitePlusP43080
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)Dockerin_dom    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    GUCA1A   
Domain families : Pfam (Sanger)EF-hand_1 (PF00036)    EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam00036    pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)GUCA1A
DMDM Disease mutations2978
Blocks (Seattle)GUCA1A
SuperfamilyP43080
Human Protein Atlas [tissue]ENSG00000048545-GUCA1A [tissue]
Peptide AtlasP43080
HPRD02648
IPIIPI00218720   IPI00745242   IPI00852589   
Protein Interaction databases
DIP (DOE-UCLA)P43080
IntAct (EBI)P43080
FunCoupENSG00000048545
BioGRIDGUCA1A
STRING (EMBL)GUCA1A
ZODIACGUCA1A
Ontologies - Pathways
QuickGOP43080
Ontology : AmiGO###############################################################################################################################################################################################################################################################                      
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                      
Pathways : BIOCARTAVisual Signal Transduction [Genes]   
Pathways : KEGGOlfactory transduction   
NDEx NetworkGUCA1A
Atlas of Cancer Signalling NetworkGUCA1A
Wikipedia pathwaysGUCA1A
Orthology - Evolution
OrthoDB2978
GeneTree (enSembl)ENSG00000048545
Phylogenetic Trees/Animal Genes : TreeFamGUCA1A
HOVERGENP43080
HOGENOMP43080
Homologs : HomoloGeneGUCA1A
Homology/Alignments : Family Browser (UCSC)GUCA1A
Gene fusions - Rearrangements
Fusion : QuiverGUCA1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGUCA1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GUCA1A
dbVarGUCA1A
ClinVarGUCA1A
1000_GenomesGUCA1A 
Exome Variant ServerGUCA1A
ExAC (Exome Aggregation Consortium)ENSG00000048545
GNOMAD BrowserENSG00000048545
Varsome BrowserGUCA1A
Genetic variants : HAPMAP2978
Genomic Variants (DGV)GUCA1A [DGVbeta]
DECIPHERGUCA1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGUCA1A 
Mutations
ICGC Data PortalGUCA1A 
TCGA Data PortalGUCA1A 
Broad Tumor PortalGUCA1A
OASIS PortalGUCA1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGUCA1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGUCA1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch GUCA1A
DgiDB (Drug Gene Interaction Database)GUCA1A
DoCM (Curated mutations)GUCA1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GUCA1A (select a term)
intoGenGUCA1A
Cancer3DGUCA1A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600364    602093   
Orphanet1843    1842   
DisGeNETGUCA1A
MedgenGUCA1A
Genetic Testing Registry GUCA1A
NextProtP43080 [Medical]
TSGene2978
GENETestsGUCA1A
Target ValidationGUCA1A
Huge Navigator GUCA1A [HugePedia]
snp3D : Map Gene to Disease2978
BioCentury BCIQGUCA1A
ClinGenGUCA1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2978
Chemical/Pharm GKB GenePA29062
Clinical trialGUCA1A
Miscellaneous
canSAR (ICR)GUCA1A (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGUCA1A
EVEXGUCA1A
GoPubMedGUCA1A
iHOPGUCA1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 13:48:20 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.