Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GUCY2F (guanylate cyclase 2F, retinal)

Identity

Alias_namesmembrane (retina-specific)
Alias_symbol (synonym)GUC2DL
GC-F
RetGC-2
ROS-GC2
CYGF
Other aliasGUC2F
RETGC-2
HGNC (Hugo) GUCY2F
LocusID (NCBI) 2986
Atlas_Id 43305
Location Xq22.3  [Link to chromosome band Xq22]
Location_base_pair Starts at 109372906 and ends at 109482056 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GUCY2F   4691
Cards
Entrez_Gene (NCBI)GUCY2F  2986  guanylate cyclase 2F, retinal
AliasesCYGF; GC-F; GUC2DL; GUC2F; 
RETGC-2; ROS-GC2
GeneCards (Weizmann)GUCY2F
Ensembl hg19 (Hinxton)ENSG00000101890 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101890 [Gene_View]  chrX:109372906-109482056 [Contig_View]  GUCY2F [Vega]
ICGC DataPortalENSG00000101890
TCGA cBioPortalGUCY2F
AceView (NCBI)GUCY2F
Genatlas (Paris)GUCY2F
WikiGenes2986
SOURCE (Princeton)GUCY2F
Genetics Home Reference (NIH)GUCY2F
Genomic and cartography
GoldenPath hg38 (UCSC)GUCY2F  -     chrX:109372906-109482056 -  Xq22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GUCY2F  -     Xq22.3   [Description]    (hg19-Feb_2009)
EnsemblGUCY2F - Xq22.3 [CytoView hg19]  GUCY2F - Xq22.3 [CytoView hg38]
Mapping of homologs : NCBIGUCY2F [Mapview hg19]  GUCY2F [Mapview hg38]
OMIM300041   
Gene and transcription
Genbank (Entrez)BC144241 BC156674 L37378
RefSeq transcript (Entrez)NM_001522
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GUCY2F
Cluster EST : UnigeneHs.123074 [ NCBI ]
CGAP (NCI)Hs.123074
Alternative Splicing GalleryENSG00000101890
Gene ExpressionGUCY2F [ NCBI-GEO ]   GUCY2F [ EBI - ARRAY_EXPRESS ]   GUCY2F [ SEEK ]   GUCY2F [ MEM ]
Gene Expression Viewer (FireBrowse)GUCY2F [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2986
GTEX Portal (Tissue expression)GUCY2F
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51841   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51841  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51841
Splice isoforms : SwissVarP51841
Catalytic activity : Enzyme4.6.1.2 [ Enzyme-Expasy ]   4.6.1.24.6.1.2 [ IntEnz-EBI ]   4.6.1.2 [ BRENDA ]   4.6.1.2 [ KEGG ]   
PhosPhoSitePlusP51841
Domaine pattern : Prosite (Expaxy)GUANYLATE_CYCLASE_1 (PS00452)    GUANYLATE_CYCLASE_2 (PS50125)    PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)A/G_cyclase    A/G_cyclase_CS    ANF_lig-bd_rcpt    HNOB_dom_associated    Kinase-like_dom    Nucleotide_cyclase    Peripla_BP_I    Prot_kinase_dom    Ser-Thr/Tyr_kinase_cat_dom   
Domain families : Pfam (Sanger)ANF_receptor (PF01094)    Guanylate_cyc (PF00211)    HNOBA (PF07701)    Pkinase_Tyr (PF07714)   
Domain families : Pfam (NCBI)pfam01094    pfam00211    pfam07701    pfam07714   
Domain families : Smart (EMBL)CYCc (SM00044)  
Conserved Domain (NCBI)GUCY2F
DMDM Disease mutations2986
Blocks (Seattle)GUCY2F
SuperfamilyP51841
Human Protein AtlasENSG00000101890
Peptide AtlasP51841
HPRD02078
IPIIPI00020942   
Protein Interaction databases
DIP (DOE-UCLA)P51841
IntAct (EBI)P51841
FunCoupENSG00000101890
BioGRIDGUCY2F
STRING (EMBL)GUCY2F
ZODIACGUCY2F
Ontologies - Pathways
QuickGOP51841
Ontology : AmiGOadenylate cyclase activity  guanylate cyclase activity  guanylate cyclase activity  protein kinase activity  receptor activity  ATP binding  GTP binding  nuclear outer membrane  integral component of plasma membrane  cGMP biosynthetic process  protein phosphorylation  signal transduction  receptor guanylyl cyclase signaling pathway  visual perception  guanylate cyclase complex, soluble  regulation of rhodopsin mediated signaling pathway  intracellular signal transduction  protein homodimerization activity  protein heterodimerization activity  detection of light stimulus involved in visual perception  photoreceptor disc membrane  
Ontology : EGO-EBIadenylate cyclase activity  guanylate cyclase activity  guanylate cyclase activity  protein kinase activity  receptor activity  ATP binding  GTP binding  nuclear outer membrane  integral component of plasma membrane  cGMP biosynthetic process  protein phosphorylation  signal transduction  receptor guanylyl cyclase signaling pathway  visual perception  guanylate cyclase complex, soluble  regulation of rhodopsin mediated signaling pathway  intracellular signal transduction  protein homodimerization activity  protein heterodimerization activity  detection of light stimulus involved in visual perception  photoreceptor disc membrane  
Pathways : KEGGPurine metabolism    Phototransduction   
NDEx NetworkGUCY2F
Atlas of Cancer Signalling NetworkGUCY2F
Wikipedia pathwaysGUCY2F
Orthology - Evolution
OrthoDB2986
GeneTree (enSembl)ENSG00000101890
Phylogenetic Trees/Animal Genes : TreeFamGUCY2F
HOVERGENP51841
HOGENOMP51841
Homologs : HomoloGeneGUCY2F
Homology/Alignments : Family Browser (UCSC)GUCY2F
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGUCY2F [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GUCY2F
dbVarGUCY2F
ClinVarGUCY2F
1000_GenomesGUCY2F 
Exome Variant ServerGUCY2F
ExAC (Exome Aggregation Consortium)GUCY2F (select the gene name)
Genetic variants : HAPMAP2986
Genomic Variants (DGV)GUCY2F [DGVbeta]
DECIPHERGUCY2F [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGUCY2F 
Mutations
ICGC Data PortalGUCY2F 
TCGA Data PortalGUCY2F 
Broad Tumor PortalGUCY2F
OASIS PortalGUCY2F [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGUCY2F  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGUCY2F
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch GUCY2F
DgiDB (Drug Gene Interaction Database)GUCY2F
DoCM (Curated mutations)GUCY2F (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GUCY2F (select a term)
intoGenGUCY2F
Cancer3DGUCY2F(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300041   
Orphanet
MedgenGUCY2F
Genetic Testing Registry GUCY2F
NextProtP51841 [Medical]
TSGene2986
GENETestsGUCY2F
Target ValidationGUCY2F
Huge Navigator GUCY2F [HugePedia]
snp3D : Map Gene to Disease2986
BioCentury BCIQGUCY2F
ClinGenGUCY2F
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2986
Chemical/Pharm GKB GenePA29071
Clinical trialGUCY2F
Miscellaneous
canSAR (ICR)GUCY2F (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGUCY2F
EVEXGUCY2F
GoPubMedGUCY2F
iHOPGUCY2F
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:36:16 CEST 2017

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