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GUF1 (GUF1 homolog, GTPase)

Identity

Alias_namesGUF1 GTPase homolog (S. cerevisiae)
Alias_symbol (synonym)FLJ13220
Other aliasEF-4
EF4
EIEE40
HGNC (Hugo) GUF1
LocusID (NCBI) 60558
Atlas_Id 64119
Location 4p12  [Link to chromosome band 4p12]
Location_base_pair Starts at 44678395 and ends at 44700680 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GUF1 (4p12) / LOC100507412 (-)GUF1 (4p12) / ZNF354B (5q35.3)HUWE1 (Xp11.22) / GUF1 (4p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GUF1   25799
Cards
Entrez_Gene (NCBI)GUF1  60558  GUF1 homolog, GTPase
AliasesEF-4; EF4; EIEE40
GeneCards (Weizmann)GUF1
Ensembl hg19 (Hinxton)ENSG00000151806 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151806 [Gene_View]  chr4:44678395-44700680 [Contig_View]  GUF1 [Vega]
ICGC DataPortalENSG00000151806
TCGA cBioPortalGUF1
AceView (NCBI)GUF1
Genatlas (Paris)GUF1
WikiGenes60558
SOURCE (Princeton)GUF1
Genetics Home Reference (NIH)GUF1
Genomic and cartography
GoldenPath hg38 (UCSC)GUF1  -     chr4:44678395-44700680 +  4p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GUF1  -     4p12   [Description]    (hg19-Feb_2009)
EnsemblGUF1 - 4p12 [CytoView hg19]  GUF1 - 4p12 [CytoView hg38]
Mapping of homologs : NCBIGUF1 [Mapview hg19]  GUF1 [Mapview hg38]
OMIM617064   617065   
Gene and transcription
Genbank (Entrez)AK001607 AK023282 AK025248 AK225314 AK308667
RefSeq transcript (Entrez)NM_001345867 NM_001345868 NM_001345869 NM_021927
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GUF1
Cluster EST : UnigeneHs.546419 [ NCBI ]
CGAP (NCI)Hs.546419
Alternative Splicing GalleryENSG00000151806
Gene ExpressionGUF1 [ NCBI-GEO ]   GUF1 [ EBI - ARRAY_EXPRESS ]   GUF1 [ SEEK ]   GUF1 [ MEM ]
Gene Expression Viewer (FireBrowse)GUF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)60558
GTEX Portal (Tissue expression)GUF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N442   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N442  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N442
Splice isoforms : SwissVarQ8N442
Catalytic activity : Enzyme3.6.5.- [ Enzyme-Expasy ]   3.6.5.-3.6.5.- [ IntEnz-EBI ]   3.6.5.- [ BRENDA ]   3.6.5.- [ KEGG ]   
PhosPhoSitePlusQ8N442
Domaine pattern : Prosite (Expaxy)G_TR_1 (PS00301)    G_TR_2 (PS51722)   
Domains : Interpro (EBI)EF-4    EFG_III-V    EFG_V    EFTu-like_2    G_TR_CS    LepA_GTP-bd_C    P-loop_NTPase    Small_GTP-bd_dom    TF_GTP-bd_dom    Transl_B-barrel   
Domain families : Pfam (Sanger)EFG_C (PF00679)    GTP_EFTU_D2 (PF03144)    LepA_C (PF06421)   
Domain families : Pfam (NCBI)pfam00679    pfam03144    pfam06421   
Conserved Domain (NCBI)GUF1
DMDM Disease mutations60558
Blocks (Seattle)GUF1
SuperfamilyQ8N442
Human Protein AtlasENSG00000151806
Peptide AtlasQ8N442
HPRD07821
IPIIPI00296563   IPI00965010   
Protein Interaction databases
DIP (DOE-UCLA)Q8N442
IntAct (EBI)Q8N442
FunCoupENSG00000151806
BioGRIDGUF1
STRING (EMBL)GUF1
ZODIACGUF1
Ontologies - Pathways
QuickGOQ8N442
Ontology : AmiGOGTPase activity  GTP binding  mitochondrial inner membrane  translation  
Ontology : EGO-EBIGTPase activity  GTP binding  mitochondrial inner membrane  translation  
NDEx NetworkGUF1
Atlas of Cancer Signalling NetworkGUF1
Wikipedia pathwaysGUF1
Orthology - Evolution
OrthoDB60558
GeneTree (enSembl)ENSG00000151806
Phylogenetic Trees/Animal Genes : TreeFamGUF1
HOVERGENQ8N442
HOGENOMQ8N442
Homologs : HomoloGeneGUF1
Homology/Alignments : Family Browser (UCSC)GUF1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGUF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GUF1
dbVarGUF1
ClinVarGUF1
1000_GenomesGUF1 
Exome Variant ServerGUF1
ExAC (Exome Aggregation Consortium)GUF1 (select the gene name)
Genetic variants : HAPMAP60558
Genomic Variants (DGV)GUF1 [DGVbeta]
DECIPHERGUF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGUF1 
Mutations
ICGC Data PortalGUF1 
TCGA Data PortalGUF1 
Broad Tumor PortalGUF1
OASIS PortalGUF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGUF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGUF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GUF1
DgiDB (Drug Gene Interaction Database)GUF1
DoCM (Curated mutations)GUF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GUF1 (select a term)
intoGenGUF1
Cancer3DGUF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617064    617065   
Orphanet894   
MedgenGUF1
Genetic Testing Registry GUF1
NextProtQ8N442 [Medical]
TSGene60558
GENETestsGUF1
Target ValidationGUF1
Huge Navigator GUF1 [HugePedia]
snp3D : Map Gene to Disease60558
BioCentury BCIQGUF1
ClinGenGUF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD60558
Chemical/Pharm GKB GenePA143485485
Clinical trialGUF1
Miscellaneous
canSAR (ICR)GUF1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGUF1
EVEXGUF1
GoPubMedGUF1
iHOPGUF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:51:47 CEST 2017

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