GUF1 (GTP binding elongation factor GUF1)

2014-11-01  

Identity

HGNC
LOCATION
4p12
LOCUSID
ALIAS
DEE40,EF-4,EF4,EIEE40
FUSION GENES

Other Information

Locus ID:

NCBI: 60558
MIM: 617064
HGNC: 25799
Ensembl: ENSG00000151806

Variants:

dbSNP: 60558
ClinVar: 60558
TCGA: ENSG00000151806
COSMIC: GUF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151806ENST00000281543Q8N442
ENSG00000151806ENST00000281543A0A024R9T3
ENSG00000151806ENST00000513775D6RBJ0

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
270920032016Elongation factor 4 remodels the A-site tRNA on the ribosome.7
264864722016West syndrome caused by homozygous variant in the evolutionary conserved gene encoding the mitochondrial elongation factor GUF1.3

Citation

Dessen P

GUF1 (GTP binding elongation factor GUF1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64119/guf1