GULP1 (GULP PTB domain containing engulfment adaptor 1)

2014-08-01  

Identity

HGNC
LOCATION
2q32.1
LOCUSID
ALIAS
CED-6,CED6,GULP
FUSION GENES

Other Information

Locus ID:

NCBI: 51454
MIM: 608165
HGNC: 18649
Ensembl: ENSG00000144366

Variants:

dbSNP: 51454
ClinVar: 51454
TCGA: ENSG00000144366
COSMIC: GULP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144366ENST00000359135Q9UBP9
ENSG00000144366ENST00000409580Q9UBP9
ENSG00000144366ENST00000409609Q9UBP9
ENSG00000144366ENST00000409637Q9UBP9
ENSG00000144366ENST00000409805Q9UBP9
ENSG00000144366ENST00000409830Q9UBP9
ENSG00000144366ENST00000409843Q9UBP9
ENSG00000144366ENST00000409927B8ZZL1
ENSG00000144366ENST00000410051Q9UBP9
ENSG00000144366ENST00000433052H7BZV7
ENSG00000144366ENST00000451191H0Y6R1

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
117291932002Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP).79
182306082008Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment.38
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
191222002009Signalling pathway involving GULP, MAPK and Rac1 for SR-BI-induced phagocytosis of apoptotic cells.16
197217172009Apoptotic engulfment pathway and schizophrenia.15
197217172009Apoptotic engulfment pathway and schizophrenia.15
205997012010Adaptor protein GULP is involved in stabilin-1-mediated phagocytosis.14
214862242011GULP1 is a novel APP-interacting protein that alters APP processing.12
223987202012The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.11
224516572012Engulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells.7

Citation

Dessen P

GULP1 (GULP PTB domain containing engulfment adaptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54350/gulp1