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GUSB (glucuronidase, beta)

Identity

Other namesBG
MPS7
HGNC (Hugo) GUSB
LocusID (NCBI) 2990
Location 7q11.21
Location_base_pair Starts at 65425673 and ends at 65447301 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GUSB   4696
Cards
Entrez_Gene (NCBI)GUSB  2990  glucuronidase, beta
GeneCards (Weizmann)GUSB
Ensembl (Hinxton)ENSG00000169919 [Gene_View]  chr7:65425673-65447301 [Contig_View]  GUSB [Vega]
ICGC DataPortalENSG00000169919
AceView (NCBI)GUSB
Genatlas (Paris)GUSB
WikiGenes2990
SOURCE (Princeton)NM_000181 NM_001284290 NM_001293104 NM_001293105
Genomic and cartography
GoldenPath (UCSC)GUSB  -  7q11.21   chr7:65425673-65447301 -  7q11.21   [Description]    (hg19-Feb_2009)
EnsemblGUSB - 7q11.21 [CytoView]
Mapping of homologs : NCBIGUSB [Mapview]
OMIM253220   611499   
Gene and transcription
Genbank (Entrez)AA947121 AK096764 AK223406 AK300223 AK303819
RefSeq transcript (Entrez)NM_000181 NM_001284290 NM_001293104 NM_001293105
RefSeq genomic (Entrez)AC_000139 NC_000007 NC_018918 NG_016197 NT_007933 NW_001839038 NW_004929332
Consensus coding sequences : CCDS (NCBI)GUSB
Cluster EST : UnigeneHs.255230 [ NCBI ]
CGAP (NCI)Hs.255230
Alternative Splicing : Fast-db (Paris)GSHG0028235
Alternative Splicing GalleryENSG00000169919
Gene ExpressionGUSB [ NCBI-GEO ]     GUSB [ SEEK ]   GUSB [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08236 (Uniprot)
NextProtP08236  [Medical]
With graphics : InterProP08236
Splice isoforms : SwissVarP08236 (Swissvar)
Catalytic activity : Enzyme3.2.1.31 [ Enzyme-Expasy ]   3.2.1.313.2.1.31 [ IntEnz-EBI ]   3.2.1.31 [ BRENDA ]   3.2.1.31 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)GLYCOSYL_HYDROL_F2_1 (PS00719)    GLYCOSYL_HYDROL_F2_2 (PS00608)   
Domains : Interpro (EBI)Galactose-bd-like    Glyco_hydro_2    Glyco_hydro_2/20_Ig-like    Glyco_hydro_2_AS    Glyco_hydro_2_CS    Glyco_hydro_2_Ig-like    Glyco_hydro_2_N    Glyco_hydro_2_TIM    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Related proteins : CluSTrP08236
Domain families : Pfam (Sanger)Glyco_hydro_2 (PF00703)    Glyco_hydro_2_C (PF02836)    Glyco_hydro_2_N (PF02837)   
Domain families : Pfam (NCBI)pfam00703    pfam02836    pfam02837   
DMDM Disease mutations2990
Blocks (Seattle)P08236
PDB (SRS)1BHG    3HN3   
PDB (PDBSum)1BHG    3HN3   
PDB (IMB)1BHG    3HN3   
PDB (RSDB)1BHG    3HN3   
Human Protein AtlasENSG00000169919
Peptide AtlasP08236
HPRD02018
IPIIPI00027745   IPI00219516   IPI00969546   IPI00927883   IPI00924575   IPI00924795   IPI01012614   
Protein Interaction databases
DIP (DOE-UCLA)P08236
IntAct (EBI)P08236
FunCoupENSG00000169919
BioGRIDGUSB
InParanoidP08236
Interologous Interaction database P08236
IntegromeDBGUSB
STRING (EMBL)GUSB
Ontologies - Pathways
Ontology : AmiGObeta-glucuronidase activity  carbohydrate metabolic process  glycosaminoglycan catabolic process  membrane  glycosaminoglycan metabolic process  hyaluronan metabolic process  hyaluronan catabolic process  lysosomal lumen  intracellular membrane-bounded organelle  small molecule metabolic process  extracellular vesicular exosome  
Ontology : EGO-EBIbeta-glucuronidase activity  carbohydrate metabolic process  glycosaminoglycan catabolic process  membrane  glycosaminoglycan metabolic process  hyaluronan metabolic process  hyaluronan catabolic process  lysosomal lumen  intracellular membrane-bounded organelle  small molecule metabolic process  extracellular vesicular exosome  
Pathways : KEGGPentose and glucuronate interconversions    Starch and sucrose metabolism    Glycosaminoglycan degradation    Porphyrin and chlorophyll metabolism    Drug metabolism - other enzymes    Lysosome   
Protein Interaction DatabaseGUSB
Wikipedia pathwaysGUSB
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GUSB
SNP (GeneSNP Utah)GUSB
SNP : HGBaseGUSB
Genetic variants : HAPMAPGUSB
1000_GenomesGUSB 
ICGC programENSG00000169919 
CONAN: Copy Number AnalysisGUSB 
Somatic Mutations in Cancer : COSMICGUSB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDGUSB
OMIM253220    611499   
MedgenGUSB
GENETestsGUSB
Disease Genetic AssociationGUSB
Huge Navigator GUSB [HugePedia]  GUSB [HugeCancerGEM]
Genomic VariantsGUSB  GUSB [DGVbeta]
Exome VariantGUSB
dbVarGUSB
ClinVarGUSB
snp3D : Map Gene to Disease2990
General knowledge
Homologs : HomoloGeneGUSB
Homology/Alignments : Family Browser (UCSC)GUSB
Phylogenetic Trees/Animal Genes : TreeFamGUSB
Chemical/Protein Interactions : CTD2990
Chemical/Pharm GKB GenePA29075
Clinical trialGUSB
Cancer Resource (Charite)ENSG00000169919
Other databases
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
CoreMineGUSB
iHOPGUSB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 12:49:41 CEST 2014

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