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GYS2 (glycogen synthase 2)

Identity

Alias (NCBI)-
HGNC (Hugo) GYS2
HGNC Previous nameglycogen synthase 2 (liver)
LocusID (NCBI) 2998
Atlas_Id 58236
Location 12p12.1  [Link to chromosome band 12p12]
Location_base_pair Starts at 21536107 and ends at 21604847 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EPS8 (12p12.3) / GYS2 (12p12.1)FAM222B (17q11.2) / GYS2 (12p12.1)SAA1 (11p15.1) / GYS2 (12p12.1)
SAA3P (11p15.1) / GYS2 (12p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GYS2   4707
Cards
Entrez_Gene (NCBI)GYS2    glycogen synthase 2
Aliases
GeneCards (Weizmann)GYS2
Ensembl hg19 (Hinxton)ENSG00000111713 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111713 [Gene_View]  ENSG00000111713 [Sequence]  chr12:21536107-21604847 [Contig_View]  GYS2 [Vega]
ICGC DataPortalENSG00000111713
TCGA cBioPortalGYS2
AceView (NCBI)GYS2
Genatlas (Paris)GYS2
SOURCE (Princeton)GYS2
Genetics Home Reference (NIH)GYS2
Genomic and cartography
GoldenPath hg38 (UCSC)GYS2  -     chr12:21536107-21604847 -  12p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GYS2  -     12p12.1   [Description]    (hg19-Feb_2009)
GoldenPathGYS2 - 12p12.1 [CytoView hg19]  GYS2 - 12p12.1 [CytoView hg38]
ImmunoBaseENSG00000111713
Genome Data Viewer NCBIGYS2 [Mapview hg19]  
OMIM138571   240600   
Gene and transcription
Genbank (Entrez)AK308373 AV653197 BC126310 BC126312 D29685
RefSeq transcript (Entrez)NM_021957
Consensus coding sequences : CCDS (NCBI)GYS2
Gene ExpressionGYS2 [ NCBI-GEO ]   GYS2 [ EBI - ARRAY_EXPRESS ]   GYS2 [ SEEK ]   GYS2 [ MEM ]
Gene Expression Viewer (FireBrowse)GYS2 [ Firebrowse - Broad ]
GenevisibleExpression of GYS2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2998
GTEX Portal (Tissue expression)GYS2
Human Protein AtlasENSG00000111713-GYS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54840   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54840  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54840
PhosPhoSitePlusP54840
Domains : Interpro (EBI)Glycogen_synth   
Domain families : Pfam (Sanger)Glycogen_syn (PF05693)   
Domain families : Pfam (NCBI)pfam05693   
Conserved Domain (NCBI)GYS2
SuperfamilyP54840
AlphaFold pdb e-kbP54840   
Human Protein Atlas [tissue]ENSG00000111713-GYS2 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P54840
IntAct (EBI)P54840
BioGRIDGYS2
STRING (EMBL)GYS2
ZODIACGYS2
Ontologies - Pathways
QuickGOP54840
Ontology : AmiGOglycogen (starch) synthase activity  glycogen (starch) synthase activity  glycogen (starch) synthase activity  glycogen (starch) synthase activity  cytoplasm  cytoplasm  cytosol  cytosol  cytoskeleton  cell cortex  glycogen biosynthetic process  glycogen biosynthetic process  glycogen biosynthetic process  glycogen biosynthetic process  glycogen biosynthetic process  generation of precursor metabolites and energy  response to glucose  cortical actin cytoskeleton  ectoplasm  
Ontology : EGO-EBIglycogen (starch) synthase activity  glycogen (starch) synthase activity  glycogen (starch) synthase activity  glycogen (starch) synthase activity  cytoplasm  cytoplasm  cytosol  cytosol  cytoskeleton  cell cortex  glycogen biosynthetic process  glycogen biosynthetic process  glycogen biosynthetic process  glycogen biosynthetic process  glycogen biosynthetic process  generation of precursor metabolites and energy  response to glucose  cortical actin cytoskeleton  ectoplasm  
Pathways : KEGGStarch and sucrose metabolism    PI3K-Akt signaling pathway    Insulin signaling pathway   
NDEx NetworkGYS2
Atlas of Cancer Signalling NetworkGYS2
Wikipedia pathwaysGYS2
Orthology - Evolution
OrthoDB2998
GeneTree (enSembl)ENSG00000111713
Phylogenetic Trees/Animal Genes : TreeFamGYS2
Homologs : HomoloGeneGYS2
Homology/Alignments : Family Browser (UCSC)GYS2
Gene fusions - Rearrangements
Fusion : QuiverGYS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGYS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GYS2
dbVarGYS2
ClinVarGYS2
MonarchGYS2
1000_GenomesGYS2 
Exome Variant ServerGYS2
GNOMAD BrowserENSG00000111713
Varsome BrowserGYS2
ACMGGYS2 variants
VarityP54840
Genomic Variants (DGV)GYS2 [DGVbeta]
DECIPHERGYS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGYS2 
Mutations
ICGC Data PortalGYS2 
TCGA Data PortalGYS2 
Broad Tumor PortalGYS2
OASIS PortalGYS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGYS2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGYS2
Mutations and Diseases : HGMDGYS2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGYS2
DgiDB (Drug Gene Interaction Database)GYS2
DoCM (Curated mutations)GYS2
CIViC (Clinical Interpretations of Variants in Cancer)GYS2
Cancer3DGYS2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138571    240600   
Orphanet
DisGeNETGYS2
MedgenGYS2
Genetic Testing Registry GYS2
NextProtP54840 [Medical]
GENETestsGYS2
Target ValidationGYS2
Huge Navigator GYS2 [HugePedia]
ClinGenGYS2
Clinical trials, drugs, therapy
MyCancerGenomeGYS2
Protein Interactions : CTDGYS2
PharosP54840
Clinical trialGYS2
Miscellaneous
canSAR (ICR)GYS2
HarmonizomeGYS2
DataMed IndexGYS2
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGYS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:11:48 CEST 2021

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