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GZMM (granzyme M)

Identity

Alias_namesgranzyme M (lymphocyte met-ase 1)
Alias_symbol (synonym)MET1
LMET1
Other alias
HGNC (Hugo) GZMM
LocusID (NCBI) 3004
Atlas_Id 43668
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 544034 and ends at 549920 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BSG (19p13.3) / GZMM (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GZMM   4712
Cards
Entrez_Gene (NCBI)GZMM  3004  granzyme M
AliasesLMET1; MET1
GeneCards (Weizmann)GZMM
Ensembl hg19 (Hinxton)ENSG00000197540 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197540 [Gene_View]  chr19:544034-549920 [Contig_View]  GZMM [Vega]
ICGC DataPortalENSG00000197540
TCGA cBioPortalGZMM
AceView (NCBI)GZMM
Genatlas (Paris)GZMM
WikiGenes3004
SOURCE (Princeton)GZMM
Genetics Home Reference (NIH)GZMM
Genomic and cartography
GoldenPath hg38 (UCSC)GZMM  -     chr19:544034-549920 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GZMM  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblGZMM - 19p13.3 [CytoView hg19]  GZMM - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIGZMM [Mapview hg19]  GZMM [Mapview hg38]
OMIM600311   
Gene and transcription
Genbank (Entrez)BC025701 CD366947 CR991101 HQ257986 L23134
RefSeq transcript (Entrez)NM_001258351 NM_005317
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GZMM
Cluster EST : UnigeneHs.465511 [ NCBI ]
CGAP (NCI)Hs.465511
Alternative Splicing GalleryENSG00000197540
Gene ExpressionGZMM [ NCBI-GEO ]   GZMM [ EBI - ARRAY_EXPRESS ]   GZMM [ SEEK ]   GZMM [ MEM ]
Gene Expression Viewer (FireBrowse)GZMM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3004
GTEX Portal (Tissue expression)GZMM
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51124   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51124  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51124
Splice isoforms : SwissVarP51124
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusP51124
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)GZMM    Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)GZMM
DMDM Disease mutations3004
Blocks (Seattle)GZMM
PDB (SRS)1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
PDB (PDBSum)1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
PDB (IMB)1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
PDB (RSDB)1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
Structural Biology KnowledgeBase1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
SCOP (Structural Classification of Proteins)1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
CATH (Classification of proteins structures)1LZP    2ZGC    2ZGH    2ZGJ    2ZKS   
SuperfamilyP51124
Human Protein AtlasENSG00000197540
Peptide AtlasP51124
HPRD02633
IPIIPI00016282   
Protein Interaction databases
DIP (DOE-UCLA)P51124
IntAct (EBI)P51124
FunCoupENSG00000197540
BioGRIDGZMM
STRING (EMBL)GZMM
ZODIACGZMM
Ontologies - Pathways
QuickGOP51124
Ontology : AmiGOserine-type endopeptidase activity  protein binding  extracellular region  proteolysis  apoptotic process  cell death  serine-type peptidase activity  membrane  cytolysis  innate immune response  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  extracellular region  proteolysis  apoptotic process  cell death  serine-type peptidase activity  membrane  cytolysis  innate immune response  
NDEx NetworkGZMM
Atlas of Cancer Signalling NetworkGZMM
Wikipedia pathwaysGZMM
Orthology - Evolution
OrthoDB3004
GeneTree (enSembl)ENSG00000197540
Phylogenetic Trees/Animal Genes : TreeFamGZMM
HOVERGENP51124
HOGENOMP51124
Homologs : HomoloGeneGZMM
Homology/Alignments : Family Browser (UCSC)GZMM
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGZMM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GZMM
dbVarGZMM
ClinVarGZMM
1000_GenomesGZMM 
Exome Variant ServerGZMM
ExAC (Exome Aggregation Consortium)GZMM (select the gene name)
Genetic variants : HAPMAP3004
Genomic Variants (DGV)GZMM [DGVbeta]
DECIPHERGZMM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGZMM 
Mutations
ICGC Data PortalGZMM 
TCGA Data PortalGZMM 
Broad Tumor PortalGZMM
OASIS PortalGZMM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGZMM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGZMM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GZMM
DgiDB (Drug Gene Interaction Database)GZMM
DoCM (Curated mutations)GZMM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GZMM (select a term)
intoGenGZMM
Cancer3DGZMM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600311   
Orphanet
MedgenGZMM
Genetic Testing Registry GZMM
NextProtP51124 [Medical]
TSGene3004
GENETestsGZMM
Target ValidationGZMM
Huge Navigator GZMM [HugePedia]
snp3D : Map Gene to Disease3004
BioCentury BCIQGZMM
ClinGenGZMM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3004
Chemical/Pharm GKB GenePA29090
Clinical trialGZMM
Miscellaneous
canSAR (ICR)GZMM (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGZMM
EVEXGZMM
GoPubMedGZMM
iHOPGZMM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:36:17 CEST 2017

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