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H1-0 (H1.0 linker histone)

Identity

Alias (NCBI)H1.0
H10
H1F0
H1FV
HGNC (Hugo) H1-0
HGNC Alias symbH1.0
HGNC Alias nameH1.0, H1(0), H1-0
HGNC Previous nameH1FV
 H1F0
HGNC Previous nameH1 histone family, member 0
 H1 histone family member 0
LocusID (NCBI) 3005
Atlas_Id 58100
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37805229 and ends at 37807431 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H1-0   4714
Cards
Entrez_Gene (NCBI)H1-0  3005  H1.0 linker histone
AliasesH1.0; H10; H1F0; H1FV
GeneCards (Weizmann)H1-0
Ensembl hg19 (Hinxton)ENSG00000189060 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189060 [Gene_View]  ENSG00000189060 [Sequence]  chr22:37805229-37807431 [Contig_View]  H1-0 [Vega]
ICGC DataPortalENSG00000189060
TCGA cBioPortalH1-0
AceView (NCBI)H1-0
Genatlas (Paris)H1-0
WikiGenes3005
SOURCE (Princeton)H1-0
Genetics Home Reference (NIH)H1-0
Genomic and cartography
GoldenPath hg38 (UCSC)H1-0  -     chr22:37805229-37807431 +  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H1-0  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH1-0 - - [CytoView hg19]  H1-0 - - [CytoView hg38]
ImmunoBaseENSG00000189060
genome Data Viewer NCBIH1-0 [Mapview hg19]  
OMIM142708   
Gene and transcription
Genbank (Entrez)AA206831 AK091372 AK299209 AK312583 BC000145
RefSeq transcript (Entrez)NM_005318
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H1-0
Alternative Splicing GalleryENSG00000189060
Gene ExpressionH1-0 [ NCBI-GEO ]   H1-0 [ EBI - ARRAY_EXPRESS ]   H1-0 [ SEEK ]   H1-0 [ MEM ]
Gene Expression Viewer (FireBrowse)H1-0 [ Firebrowse - Broad ]
GenevisibleExpression of H1-0 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3005
GTEX Portal (Tissue expression)H1-0
Human Protein AtlasENSG00000189060-H1-0 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07305   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07305  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07305
Splice isoforms : SwissVarP07305
PhosPhoSitePlusP07305
Domaine pattern : Prosite (Expaxy)H15 (PS51504)   
Domains : Interpro (EBI)Histone_H1/H5_H15    Histone_H5    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Linker_histone (PF00538)   
Domain families : Pfam (NCBI)pfam00538   
Domain families : Smart (EMBL)H15 (SM00526)  
Conserved Domain (NCBI)H1-0
DMDM Disease mutations3005
Blocks (Seattle)H1-0
PDB (RSDB)6HQ1    6N88    6N89   
PDB Europe6HQ1    6N88    6N89   
PDB (PDBSum)6HQ1    6N88    6N89   
PDB (IMB)6HQ1    6N88    6N89   
Structural Biology KnowledgeBase6HQ1    6N88    6N89   
SCOP (Structural Classification of Proteins)6HQ1    6N88    6N89   
CATH (Classification of proteins structures)6HQ1    6N88    6N89   
SuperfamilyP07305
Human Protein Atlas [tissue]ENSG00000189060-H1-0 [tissue]
Peptide AtlasP07305
IPIIPI00550239   IPI00979041   
Protein Interaction databases
DIP (DOE-UCLA)P07305
IntAct (EBI)P07305
FunCoupENSG00000189060
BioGRIDH1-0
STRING (EMBL)H1-0
ZODIACH1-0
Ontologies - Pathways
QuickGOP07305
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nucleosome  nuclear chromatin  AT DNA binding  double-stranded DNA binding  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  nuclear euchromatin  Golgi apparatus  apoptotic DNA fragmentation  nucleosome assembly  chromatin silencing  regulation of transcription, DNA-templated  actin cytoskeleton  nucleosome positioning  nuclear body  transcriptional repressor complex  chromosome condensation  chromatin DNA binding  nucleosomal DNA binding  negative regulation of chromatin silencing  host cell nucleus  negative regulation of DNA recombination  positive regulation of transcription regulatory region DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nucleosome  nuclear chromatin  AT DNA binding  double-stranded DNA binding  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  nuclear euchromatin  Golgi apparatus  apoptotic DNA fragmentation  nucleosome assembly  chromatin silencing  regulation of transcription, DNA-templated  actin cytoskeleton  nucleosome positioning  nuclear body  transcriptional repressor complex  chromosome condensation  chromatin DNA binding  nucleosomal DNA binding  negative regulation of chromatin silencing  host cell nucleus  negative regulation of DNA recombination  positive regulation of transcription regulatory region DNA binding  
NDEx NetworkH1-0
Atlas of Cancer Signalling NetworkH1-0
Wikipedia pathwaysH1-0
Orthology - Evolution
OrthoDB3005
GeneTree (enSembl)ENSG00000189060
Phylogenetic Trees/Animal Genes : TreeFamH1-0
HOGENOMP07305
Homologs : HomoloGeneH1-0
Homology/Alignments : Family Browser (UCSC)H1-0
Gene fusions - Rearrangements
Fusion : QuiverH1-0
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH1-0 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H1-0
dbVarH1-0
ClinVarH1-0
1000_GenomesH1-0 
Exome Variant ServerH1-0
GNOMAD BrowserENSG00000189060
Varsome BrowserH1-0
Genetic variants : HAPMAP3005
Genomic Variants (DGV)H1-0 [DGVbeta]
DECIPHERH1-0 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH1-0 
Mutations
ICGC Data PortalH1-0 
TCGA Data PortalH1-0 
Broad Tumor PortalH1-0
OASIS PortalH1-0 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH1-0
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H1-0
DgiDB (Drug Gene Interaction Database)H1-0
DoCM (Curated mutations)H1-0 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H1-0 (select a term)
intoGenH1-0
Cancer3DH1-0(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142708   
Orphanet
DisGeNETH1-0
MedgenH1-0
Genetic Testing Registry H1-0
NextProtP07305 [Medical]
TSGene3005
GENETestsH1-0
Target ValidationH1-0
Huge Navigator H1-0 [HugePedia]
snp3D : Map Gene to Disease3005
BioCentury BCIQH1-0
ClinGenH1-0
Clinical trials, drugs, therapy
Protein Interactions : CTD3005
Clinical trialH1-0
Miscellaneous
canSAR (ICR)H1-0 (select the gene name)
HarmonizomeH1-0
DataMed IndexH1-0
Probes
Litterature
PubMed101 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH1-0
EVEXH1-0
GoPubMedH1-0
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jul 16 15:15:58 CEST 2020

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