Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

H1-3 (H1.3 linker histone, cluster member)

Identity

Alias_namesH1F3
HIST1H1D
H1 histone family, member 3
histone 1, H1d
histone cluster 1, H1d
histone cluster 1 H1 family member d
Alias_symbol (synonym)H1.3
H1d
H1s-2
Other aliasH1D
HGNC (Hugo) H1-3
LocusID (NCBI) 3007
Atlas_Id 53901
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26234212 and ends at 26234988 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H1-3   4717
Cards
Entrez_Gene (NCBI)H1-3  3007  H1.3 linker histone, cluster member
AliasesH1.3; H1D; H1F3; H1s-2; 
HIST1H1D
GeneCards (Weizmann)H1-3
Ensembl hg19 (Hinxton)ENSG00000124575 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124575 [Gene_View]  ENSG00000124575 [Sequence]  chr6:26234212-26234988 [Contig_View]  H1-3 [Vega]
ICGC DataPortalENSG00000124575
TCGA cBioPortalH1-3
AceView (NCBI)H1-3
Genatlas (Paris)H1-3
WikiGenes3007
SOURCE (Princeton)H1-3
Genetics Home Reference (NIH)H1-3
Genomic and cartography
GoldenPath hg38 (UCSC)H1-3  -     chr6:26234212-26234988 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H1-3  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH1-3 - - [CytoView hg19]  H1-3 - - [CytoView hg38]
ImmunoBaseENSG00000124575
Mapping of homologs : NCBIH1-3 [Mapview hg19]  H1-3 [Mapview hg38]
OMIM142210   
Gene and transcription
Genbank (Entrez)AK312845 BC104874 BC111971
RefSeq transcript (Entrez)NM_005320
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H1-3
Alternative Splicing GalleryENSG00000124575
Gene ExpressionH1-3 [ NCBI-GEO ]   H1-3 [ EBI - ARRAY_EXPRESS ]   H1-3 [ SEEK ]   H1-3 [ MEM ]
Gene Expression Viewer (FireBrowse)H1-3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3007
GTEX Portal (Tissue expression)H1-3
Human Protein AtlasENSG00000124575-H1-3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16402   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16402  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16402
Splice isoforms : SwissVarP16402
PhosPhoSitePlusP16402
Domaine pattern : Prosite (Expaxy)H15 (PS51504)   
Domains : Interpro (EBI)Histone_H1/H5_H15    Histone_H5    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Linker_histone (PF00538)   
Domain families : Pfam (NCBI)pfam00538   
Domain families : Smart (EMBL)H15 (SM00526)  
Conserved Domain (NCBI)H1-3
DMDM Disease mutations3007
Blocks (Seattle)H1-3
SuperfamilyP16402
Human Protein Atlas [tissue]ENSG00000124575-H1-3 [tissue]
Peptide AtlasP16402
HPRD06764
IPIIPI00217466   
Protein Interaction databases
DIP (DOE-UCLA)P16402
IntAct (EBI)P16402
FunCoupENSG00000124575
BioGRIDH1-3
STRING (EMBL)H1-3
ZODIACH1-3
Ontologies - Pathways
QuickGOP16402
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nucleosome  nuclear chromatin  nuclear chromatin  double-stranded DNA binding  RNA binding  nucleus  nuclear euchromatin  nuclear euchromatin  nucleosome assembly  regulation of transcription, DNA-templated  nucleosome positioning  chromosome condensation  chromatin DNA binding  nucleosomal DNA binding  negative regulation of chromatin silencing  negative regulation of DNA recombination  histone H3-K4 trimethylation  histone H3-K27 trimethylation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nucleosome  nuclear chromatin  nuclear chromatin  double-stranded DNA binding  RNA binding  nucleus  nuclear euchromatin  nuclear euchromatin  nucleosome assembly  regulation of transcription, DNA-templated  nucleosome positioning  chromosome condensation  chromatin DNA binding  nucleosomal DNA binding  negative regulation of chromatin silencing  negative regulation of DNA recombination  histone H3-K4 trimethylation  histone H3-K27 trimethylation  
NDEx NetworkH1-3
Atlas of Cancer Signalling NetworkH1-3
Wikipedia pathwaysH1-3
Orthology - Evolution
OrthoDB3007
GeneTree (enSembl)ENSG00000124575
Phylogenetic Trees/Animal Genes : TreeFamH1-3
HOGENOMP16402
Homologs : HomoloGeneH1-3
Homology/Alignments : Family Browser (UCSC)H1-3
Gene fusions - Rearrangements
Fusion : QuiverH1-3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH1-3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H1-3
dbVarH1-3
ClinVarH1-3
1000_GenomesH1-3 
Exome Variant ServerH1-3
ExAC (Exome Aggregation Consortium)ENSG00000124575
GNOMAD BrowserENSG00000124575
Varsome BrowserH1-3
Genetic variants : HAPMAP3007
Genomic Variants (DGV)H1-3 [DGVbeta]
DECIPHERH1-3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH1-3 
Mutations
ICGC Data PortalH1-3 
TCGA Data PortalH1-3 
Broad Tumor PortalH1-3
OASIS PortalH1-3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH1-3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H1-3
DgiDB (Drug Gene Interaction Database)H1-3
DoCM (Curated mutations)H1-3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H1-3 (select a term)
intoGenH1-3
Cancer3DH1-3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142210   
Orphanet
DisGeNETH1-3
MedgenH1-3
Genetic Testing Registry H1-3
NextProtP16402 [Medical]
TSGene3007
GENETestsH1-3
Target ValidationH1-3
Huge Navigator H1-3 [HugePedia]
snp3D : Map Gene to Disease3007
BioCentury BCIQH1-3
ClinGenH1-3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3007
Chemical/Pharm GKB GenePA29095
Clinical trialH1-3
Miscellaneous
canSAR (ICR)H1-3 (select the gene name)
HarmonizomeH1-3
DataMed IndexH1-3
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH1-3
EVEXH1-3
GoPubMedH1-3
iHOPH1-3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Mar 11 19:09:43 CET 2020

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.