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H2AC21 (H2A clustered histone 21)

Identity

Alias (NCBI)H2AB
HIST2H2AB
HGNC (Hugo) H2AC21
HGNC Previous nameHIST2H2AB
HGNC Previous namehistone 2, H2ab
 histone cluster 2, H2ab
 histone cluster 2 H2A family member b
LocusID (NCBI) 317772
Atlas_Id 58108
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 149887469 and ends at 149887965 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H2AC21   20508
Cards
Entrez_Gene (NCBI)H2AC21  317772  H2A clustered histone 21
AliasesH2AB; HIST2H2AB
GeneCards (Weizmann)H2AC21
Ensembl hg19 (Hinxton)ENSG00000184270 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184270 [Gene_View]  ENSG00000184270 [Sequence]  chr1:149887469-149887965 [Contig_View]  H2AC21 [Vega]
ICGC DataPortalENSG00000184270
TCGA cBioPortalH2AC21
AceView (NCBI)H2AC21
Genatlas (Paris)H2AC21
WikiGenes317772
SOURCE (Princeton)H2AC21
Genetics Home Reference (NIH)H2AC21
Genomic and cartography
GoldenPath hg38 (UCSC)H2AC21  -     chr1:149887469-149887965 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H2AC21  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH2AC21 - - [CytoView hg19]  H2AC21 - - [CytoView hg38]
ImmunoBaseENSG00000184270
genome Data Viewer NCBIH2AC21 [Mapview hg19]  
OMIM615014   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_175065
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H2AC21
Alternative Splicing GalleryENSG00000184270
Gene ExpressionH2AC21 [ NCBI-GEO ]   H2AC21 [ EBI - ARRAY_EXPRESS ]   H2AC21 [ SEEK ]   H2AC21 [ MEM ]
Gene Expression Viewer (FireBrowse)H2AC21 [ Firebrowse - Broad ]
GenevisibleExpression of H2AC21 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)317772
GTEX Portal (Tissue expression)H2AC21
Human Protein AtlasENSG00000184270-H2AC21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUE6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IUE6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IUE6
Splice isoforms : SwissVarQ8IUE6
PhosPhoSitePlusQ8IUE6
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)H2AC21
DMDM Disease mutations317772
Blocks (Seattle)H2AC21
SuperfamilyQ8IUE6
Human Protein Atlas [tissue]ENSG00000184270-H2AC21 [tissue]
Peptide AtlasQ8IUE6
IPIIPI00216730   
Protein Interaction databases
DIP (DOE-UCLA)Q8IUE6
IntAct (EBI)Q8IUE6
FunCoupENSG00000184270
BioGRIDH2AC21
STRING (EMBL)H2AC21
ZODIACH2AC21
Ontologies - Pathways
QuickGOQ8IUE6
Ontology : AmiGOnucleosome  nuclear chromatin  molecular_function  DNA binding  protein binding  nucleus  chromatin organization  chromatin silencing  biological_process  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  molecular_function  DNA binding  protein binding  nucleus  chromatin organization  chromatin silencing  biological_process  protein heterodimerization activity  extracellular exosome  
NDEx NetworkH2AC21
Atlas of Cancer Signalling NetworkH2AC21
Wikipedia pathwaysH2AC21
Orthology - Evolution
OrthoDB317772
GeneTree (enSembl)ENSG00000184270
Phylogenetic Trees/Animal Genes : TreeFamH2AC21
HOGENOMQ8IUE6
Homologs : HomoloGeneH2AC21
Homology/Alignments : Family Browser (UCSC)H2AC21
Gene fusions - Rearrangements
Fusion : QuiverH2AC21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH2AC21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H2AC21
dbVarH2AC21
ClinVarH2AC21
1000_GenomesH2AC21 
Exome Variant ServerH2AC21
GNOMAD BrowserENSG00000184270
Varsome BrowserH2AC21
Genetic variants : HAPMAP317772
Genomic Variants (DGV)H2AC21 [DGVbeta]
DECIPHERH2AC21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH2AC21 
Mutations
ICGC Data PortalH2AC21 
TCGA Data PortalH2AC21 
Broad Tumor PortalH2AC21
OASIS PortalH2AC21 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH2AC21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H2AC21
DgiDB (Drug Gene Interaction Database)H2AC21
DoCM (Curated mutations)H2AC21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H2AC21 (select a term)
intoGenH2AC21
Cancer3DH2AC21(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615014   
Orphanet
DisGeNETH2AC21
MedgenH2AC21
Genetic Testing Registry H2AC21
NextProtQ8IUE6 [Medical]
TSGene317772
GENETestsH2AC21
Target ValidationH2AC21
Huge Navigator H2AC21 [HugePedia]
snp3D : Map Gene to Disease317772
BioCentury BCIQH2AC21
ClinGenH2AC21
Clinical trials, drugs, therapy
Protein Interactions : CTD317772
Clinical trialH2AC21
Miscellaneous
canSAR (ICR)H2AC21 (select the gene name)
HarmonizomeH2AC21
DataMed IndexH2AC21
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH2AC21
EVEXH2AC21
GoPubMedH2AC21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:16:01 CEST 2020

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