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H2AC6 (H2A clustered histone 6)

Identity

Alias (NCBI)H2A/l
H2AFL
HIST1H2AC
dJ221C16.4
HGNC (Hugo) H2AC6
HGNC Previous nameH2AFL
 HIST1H2AC
HGNC Previous nameH2A histone family, member L
 histone 1, H2ac
 histone cluster 1, H2ac
 histone cluster 1 H2A family member c
LocusID (NCBI) 8334
Atlas_Id 58109
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26124172 and ends at 26124690 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

Nomenclature
HGNC (Hugo)H2AC6   4733
Cards
Entrez_Gene (NCBI)H2AC6  8334  H2A clustered histone 6
AliasesH2A/l; H2AFL; HIST1H2AC; dJ221C16.4
GeneCards (Weizmann)H2AC6
Ensembl hg19 (Hinxton)ENSG00000180573 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180573 [Gene_View]  ENSG00000180573 [Sequence]  chr6:26124172-26124690 [Contig_View]  H2AC6 [Vega]
ICGC DataPortalENSG00000180573
TCGA cBioPortalH2AC6
AceView (NCBI)H2AC6
Genatlas (Paris)H2AC6
WikiGenes8334
SOURCE (Princeton)H2AC6
Genetics Home Reference (NIH)H2AC6
Genomic and cartography
GoldenPath hg38 (UCSC)H2AC6  -     chr6:26124172-26124690 +  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H2AC6  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH2AC6 - - [CytoView hg19]  H2AC6 - - [CytoView hg38]
ImmunoBaseENSG00000180573
genome Data Viewer NCBIH2AC6 [Mapview hg19]  
OMIM602794   
Gene and transcription
Genbank (Entrez)AK311811 BC017379 BC050602 BC085010 U90551
RefSeq transcript (Entrez)NM_003512
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H2AC6
Alternative Splicing GalleryENSG00000180573
Gene ExpressionH2AC6 [ NCBI-GEO ]   H2AC6 [ EBI - ARRAY_EXPRESS ]   H2AC6 [ SEEK ]   H2AC6 [ MEM ]
Gene Expression Viewer (FireBrowse)H2AC6 [ Firebrowse - Broad ]
GenevisibleExpression of H2AC6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8334
GTEX Portal (Tissue expression)H2AC6
Human Protein AtlasENSG00000180573-H2AC6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ93077   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ93077  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ93077
Splice isoforms : SwissVarQ93077
PhosPhoSitePlusQ93077
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)H2AC6
DMDM Disease mutations8334
Blocks (Seattle)H2AC6
PDB (RSDB)6C0W    6MUO    6MUP    6UPK    6UPL   
PDB Europe6C0W    6MUO    6MUP    6UPK    6UPL   
PDB (PDBSum)6C0W    6MUO    6MUP    6UPK    6UPL   
PDB (IMB)6C0W    6MUO    6MUP    6UPK    6UPL   
Structural Biology KnowledgeBase6C0W    6MUO    6MUP    6UPK    6UPL   
SCOP (Structural Classification of Proteins)6C0W    6MUO    6MUP    6UPK    6UPL   
CATH (Classification of proteins structures)6C0W    6MUO    6MUP    6UPK    6UPL   
SuperfamilyQ93077
Human Protein Atlas [tissue]ENSG00000180573-H2AC6 [tissue]
Peptide AtlasQ93077
IPIIPI00216456   
Protein Interaction databases
DIP (DOE-UCLA)Q93077
IntAct (EBI)Q93077
FunCoupENSG00000180573
BioGRIDH2AC6
STRING (EMBL)H2AC6
ZODIACH2AC6
Ontologies - Pathways
QuickGOQ93077
Ontology : AmiGOnucleosome  nuclear chromatin  molecular_function  DNA binding  nucleus  nucleus  nucleoplasm  chromatin organization  chromatin silencing  negative regulation of cell proliferation  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  molecular_function  DNA binding  nucleus  nucleus  nucleoplasm  chromatin organization  chromatin silencing  negative regulation of cell proliferation  protein heterodimerization activity  extracellular exosome  
NDEx NetworkH2AC6
Atlas of Cancer Signalling NetworkH2AC6
Wikipedia pathwaysH2AC6
Orthology - Evolution
OrthoDB8334
GeneTree (enSembl)ENSG00000180573
Phylogenetic Trees/Animal Genes : TreeFamH2AC6
HOGENOMQ93077
Homologs : HomoloGeneH2AC6
Homology/Alignments : Family Browser (UCSC)H2AC6
Gene fusions - Rearrangements
Fusion : QuiverH2AC6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH2AC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H2AC6
dbVarH2AC6
ClinVarH2AC6
MonarchH2AC6
1000_GenomesH2AC6 
Exome Variant ServerH2AC6
GNOMAD BrowserENSG00000180573
Varsome BrowserH2AC6
Genetic variants : HAPMAP8334
Genomic Variants (DGV)H2AC6 [DGVbeta]
DECIPHERH2AC6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH2AC6 
Mutations
ICGC Data PortalH2AC6 
TCGA Data PortalH2AC6 
Broad Tumor PortalH2AC6
OASIS PortalH2AC6 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH2AC6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H2AC6
DgiDB (Drug Gene Interaction Database)H2AC6
DoCM (Curated mutations)H2AC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H2AC6 (select a term)
intoGenH2AC6
Cancer3DH2AC6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602794   
Orphanet
DisGeNETH2AC6
MedgenH2AC6
Genetic Testing Registry H2AC6
NextProtQ93077 [Medical]
TSGene8334
GENETestsH2AC6
Target ValidationH2AC6
Huge Navigator H2AC6 [HugePedia]
snp3D : Map Gene to Disease8334
BioCentury BCIQH2AC6
ClinGenH2AC6
Clinical trials, drugs, therapy
Protein Interactions : CTD8334
Clinical trialH2AC6
Miscellaneous
canSAR (ICR)H2AC6 (select the gene name)
HarmonizomeH2AC6
DataMed IndexH2AC6
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH2AC6
EVEXH2AC6
GoPubMedH2AC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:13:46 CEST 2020

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