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H2AC8 (H2A clustered histone 8)

Identity

Alias (NCBI)H2A.1
H2A.2
H2A/a
H2AC4
H2AFA
HIST1H2AE
HGNC (Hugo) H2AC8
HGNC Alias symbH2A/a
H2A.1
HGNC Previous nameH2AFA
 HIST1H2AE
HGNC Previous nameH2A histone family, member A
 histone 1, H2ae
 histone cluster 1, H2ae
 histone cluster 1 H2A family member e
LocusID (NCBI) 3012
Atlas_Id 58105
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26216921 and ends at 26217483 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H2AC8   4724
Cards
Entrez_Gene (NCBI)H2AC8  3012  H2A clustered histone 8
AliasesH2A.1; H2A.2; H2A/a; H2AC4; 
H2AFA; HIST1H2AE
GeneCards (Weizmann)H2AC8
Ensembl hg19 (Hinxton)ENSG00000277075 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000277075 [Gene_View]  ENSG00000277075 [Sequence]  chr6:26216921-26217483 [Contig_View]  H2AC8 [Vega]
ICGC DataPortalENSG00000277075
TCGA cBioPortalH2AC8
AceView (NCBI)H2AC8
Genatlas (Paris)H2AC8
WikiGenes3012
SOURCE (Princeton)H2AC8
Genetics Home Reference (NIH)H2AC8
Genomic and cartography
GoldenPath hg38 (UCSC)H2AC8  -     chr6:26216921-26217483 +  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H2AC8  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH2AC8 - - [CytoView hg19]  H2AC8 - - [CytoView hg38]
ImmunoBaseENSG00000277075
genome Data Viewer NCBIH2AC8 [Mapview hg19]  
OMIM602786   
Gene and transcription
Genbank (Entrez)AK311824 BC093836 BC093862
RefSeq transcript (Entrez)NM_021052
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H2AC8
Alternative Splicing GalleryENSG00000277075
Gene ExpressionH2AC8 [ NCBI-GEO ]   H2AC8 [ EBI - ARRAY_EXPRESS ]   H2AC8 [ SEEK ]   H2AC8 [ MEM ]
Gene Expression Viewer (FireBrowse)H2AC8 [ Firebrowse - Broad ]
GenevisibleExpression of H2AC8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3012
GTEX Portal (Tissue expression)H2AC8
Human Protein AtlasENSG00000277075-H2AC8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04908   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP04908  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04908
Splice isoforms : SwissVarP04908
PhosPhoSitePlusP04908
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)H2AC8
DMDM Disease mutations3012
Blocks (Seattle)H2AC8
PDB (RSDB)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
PDB Europe2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
PDB (PDBSum)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
PDB (IMB)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
Structural Biology KnowledgeBase2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
SCOP (Structural Classification of Proteins)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
CATH (Classification of proteins structures)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    5Y0C    5Y0D    5Z23    5ZBX    6A5L    6A5O    6A5P    6A5R    6A5T    6A5U    6ACL    6AEE    6BUZ    6E0C    6E0P    6HKT    6HTS    6INQ    6IPU    6IQ4    6IR9    6J4W    6J4X    6J4Y    6J4Z    6J50    6J51    6JR0    6JR1    6JXD    6L49    6L4A    6O1D    6R8Y    6R8Z    6R90    6R91    6R92    6R93    6R94    6V92   
SuperfamilyP04908
Human Protein Atlas [tissue]ENSG00000277075-H2AC8 [tissue]
Peptide AtlasP04908
Protein Interaction databases
DIP (DOE-UCLA)P04908
IntAct (EBI)P04908
FunCoupENSG00000277075
BioGRIDH2AC8
STRING (EMBL)H2AC8
ZODIACH2AC8
Ontologies - Pathways
QuickGOP04908
Ontology : AmiGOnucleosome  nuclear chromatin  DNA binding  DNA binding  protein binding  nucleus  nucleus  chromatin organization  chromatin silencing  negative regulation of cell proliferation  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  DNA binding  DNA binding  protein binding  nucleus  nucleus  chromatin organization  chromatin silencing  negative regulation of cell proliferation  protein heterodimerization activity  extracellular exosome  
NDEx NetworkH2AC8
Atlas of Cancer Signalling NetworkH2AC8
Wikipedia pathwaysH2AC8
Orthology - Evolution
OrthoDB3012
GeneTree (enSembl)ENSG00000277075
Phylogenetic Trees/Animal Genes : TreeFamH2AC8
HOGENOMP04908
Homologs : HomoloGeneH2AC8
Homology/Alignments : Family Browser (UCSC)H2AC8
Gene fusions - Rearrangements
Fusion : QuiverH2AC8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH2AC8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H2AC8
dbVarH2AC8
ClinVarH2AC8
1000_GenomesH2AC8 
Exome Variant ServerH2AC8
GNOMAD BrowserENSG00000277075
Varsome BrowserH2AC8
Genetic variants : HAPMAP3012
Genomic Variants (DGV)H2AC8 [DGVbeta]
DECIPHERH2AC8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH2AC8 
Mutations
ICGC Data PortalH2AC8 
TCGA Data PortalH2AC8 
Broad Tumor PortalH2AC8
OASIS PortalH2AC8 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH2AC8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H2AC8
DgiDB (Drug Gene Interaction Database)H2AC8
DoCM (Curated mutations)H2AC8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H2AC8 (select a term)
intoGenH2AC8
Cancer3DH2AC8(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602786   
Orphanet
DisGeNETH2AC8
MedgenH2AC8
Genetic Testing Registry H2AC8
NextProtP04908 [Medical]
TSGene3012
GENETestsH2AC8
Target ValidationH2AC8
Huge Navigator H2AC8 [HugePedia]
snp3D : Map Gene to Disease3012
BioCentury BCIQH2AC8
ClinGenH2AC8
Clinical trials, drugs, therapy
Protein Interactions : CTD3012
Clinical trialH2AC8
Miscellaneous
canSAR (ICR)H2AC8 (select the gene name)
HarmonizomeH2AC8
DataMed IndexH2AC8
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH2AC8
EVEXH2AC8
GoPubMedH2AC8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:16:02 CEST 2020

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