Atlas of Genetics and Cytogenetics in Oncology and Haematology


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H2AZ1 (H2A.Z variant histone 1)

Identity

Alias (NCBI)H2A.Z-1
H2A.z
H2A/z
H2AFZ
H2AZ
HGNC (Hugo) H2AZ1
HGNC Alias symbH2A.Z
HGNC Previous nameH2AZ
 H2AFZ
HGNC Previous nameH2A histone family, member Z
 H2A histone family member Z
LocusID (NCBI) 3015
Atlas_Id 40784
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 99948089 and ends at 99950275 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

Nomenclature
HGNC (Hugo)H2AZ1   4741
Cards
Entrez_Gene (NCBI)H2AZ1  3015  H2A.Z variant histone 1
AliasesH2A.Z-1; H2A.z; H2A/z; H2AFZ; 
H2AZ
GeneCards (Weizmann)H2AZ1
Ensembl hg19 (Hinxton)ENSG00000164032 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164032 [Gene_View]  ENSG00000164032 [Sequence]  chr4:99948089-99950275 [Contig_View]  H2AZ1 [Vega]
ICGC DataPortalENSG00000164032
TCGA cBioPortalH2AZ1
AceView (NCBI)H2AZ1
Genatlas (Paris)H2AZ1
WikiGenes3015
SOURCE (Princeton)H2AZ1
Genetics Home Reference (NIH)H2AZ1
Genomic and cartography
GoldenPath hg38 (UCSC)H2AZ1  -     chr4:99948089-99950275 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H2AZ1  -     -   [Description]    (hg19-Feb_2009)
GoldenPathH2AZ1 - - [CytoView hg19]  H2AZ1 - - [CytoView hg38]
ImmunoBaseENSG00000164032
genome Data Viewer NCBIH2AZ1 [Mapview hg19]  
OMIM142763   
Gene and transcription
Genbank (Entrez)AK056803 AK315413 AY597416 BC018002 BC020936
RefSeq transcript (Entrez)NM_002106
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H2AZ1
Alternative Splicing GalleryENSG00000164032
Gene ExpressionH2AZ1 [ NCBI-GEO ]   H2AZ1 [ EBI - ARRAY_EXPRESS ]   H2AZ1 [ SEEK ]   H2AZ1 [ MEM ]
Gene Expression Viewer (FireBrowse)H2AZ1 [ Firebrowse - Broad ]
GenevisibleExpression of H2AZ1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3015
GTEX Portal (Tissue expression)H2AZ1
Human Protein AtlasENSG00000164032-H2AZ1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C0S5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C0S5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C0S5
Splice isoforms : SwissVarP0C0S5
PhosPhoSitePlusP0C0S5
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)H2AZ1
DMDM Disease mutations3015
Blocks (Seattle)H2AZ1
PDB (RSDB)1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
PDB Europe1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
PDB (PDBSum)1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
PDB (IMB)1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
Structural Biology KnowledgeBase1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
SCOP (Structural Classification of Proteins)1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
CATH (Classification of proteins structures)1F66    3WA9    4CAY    4NFT    5B31    5B32    5B33    5CHL    5FUG    5Z30   
SuperfamilyP0C0S5
Human Protein Atlas [tissue]ENSG00000164032-H2AZ1 [tissue]
Peptide AtlasP0C0S5
HPRD00823
IPIIPI00218448   
Protein Interaction databases
DIP (DOE-UCLA)P0C0S5
IntAct (EBI)P0C0S5
FunCoupENSG00000164032
BioGRIDH2AZ1
STRING (EMBL)H2AZ1
ZODIACH2AZ1
Ontologies - Pathways
QuickGOP0C0S5
Ontology : AmiGOnucleosome  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II core promoter sequence-specific DNA binding  Barr body  DNA binding  protein binding  nucleus  nucleus  nuclear euchromatin  nuclear heterochromatin  chromatin organization  chromatin silencing  chromatin DNA binding  nucleosomal DNA binding  positive regulation of transcription by RNA polymerase II  protein heterodimerization activity  extracellular exosome  cellular response to estradiol stimulus  
Ontology : EGO-EBInucleosome  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II core promoter sequence-specific DNA binding  Barr body  DNA binding  protein binding  nucleus  nucleus  nuclear euchromatin  nuclear heterochromatin  chromatin organization  chromatin silencing  chromatin DNA binding  nucleosomal DNA binding  positive regulation of transcription by RNA polymerase II  protein heterodimerization activity  extracellular exosome  cellular response to estradiol stimulus  
NDEx NetworkH2AZ1
Atlas of Cancer Signalling NetworkH2AZ1
Wikipedia pathwaysH2AZ1
Orthology - Evolution
OrthoDB3015
GeneTree (enSembl)ENSG00000164032
Phylogenetic Trees/Animal Genes : TreeFamH2AZ1
HOGENOMP0C0S5
Homologs : HomoloGeneH2AZ1
Homology/Alignments : Family Browser (UCSC)H2AZ1
Gene fusions - Rearrangements
Fusion : QuiverH2AZ1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH2AZ1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H2AZ1
dbVarH2AZ1
ClinVarH2AZ1
MonarchH2AZ1
1000_GenomesH2AZ1 
Exome Variant ServerH2AZ1
GNOMAD BrowserENSG00000164032
Varsome BrowserH2AZ1
Genetic variants : HAPMAP3015
Genomic Variants (DGV)H2AZ1 [DGVbeta]
DECIPHERH2AZ1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH2AZ1 
Mutations
ICGC Data PortalH2AZ1 
TCGA Data PortalH2AZ1 
Broad Tumor PortalH2AZ1
OASIS PortalH2AZ1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH2AZ1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H2AZ1
DgiDB (Drug Gene Interaction Database)H2AZ1
DoCM (Curated mutations)H2AZ1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H2AZ1 (select a term)
intoGenH2AZ1
Cancer3DH2AZ1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142763   
Orphanet
DisGeNETH2AZ1
MedgenH2AZ1
Genetic Testing Registry H2AZ1
NextProtP0C0S5 [Medical]
TSGene3015
GENETestsH2AZ1
Target ValidationH2AZ1
Huge Navigator H2AZ1 [HugePedia]
snp3D : Map Gene to Disease3015
BioCentury BCIQH2AZ1
ClinGenH2AZ1
Clinical trials, drugs, therapy
Protein Interactions : CTD3015
Clinical trialH2AZ1
Miscellaneous
canSAR (ICR)H2AZ1 (select the gene name)
HarmonizomeH2AZ1
DataMed IndexH2AZ1
Probes
Litterature
PubMed151 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH2AZ1
EVEXH2AZ1
GoPubMedH2AZ1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:13:46 CEST 2020

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