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H2BC1 (H2B clustered histone 1)

Identity

Alias_namesHIST1H2BA
H2B histone family, member U, (testis-specific)
histone 1, H2ba
histone cluster 1, H2ba
histone cluster 1 H2B family member a
Alias_symbol (synonym)bA317E16.3
STBP
TSH2B
H2BFU
Other aliasTH2B
TSH2B.1
hTSH2B
HGNC (Hugo) H2BC1
LocusID (NCBI) 255626
Atlas_Id 58141
Location 6p22.2  [Link to chromosome band 6p22]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H2BC1   18730
Cards
Entrez_Gene (NCBI)H2BC1  255626  H2B clustered histone 1
AliasesH2BFU; HIST1H2BA; STBP; TH2B; 
TSH2B; TSH2B.1; bA317E16.3; hTSH2B
GeneCards (Weizmann)H2BC1
Ensembl hg19 (Hinxton)ENSG00000146047 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146047 [Gene_View]  ENSG00000146047 [Sequence]  - [Contig_View]  H2BC1 [Vega]
ICGC DataPortalENSG00000146047
TCGA cBioPortalH2BC1
AceView (NCBI)H2BC1
Genatlas (Paris)H2BC1
WikiGenes255626
SOURCE (Princeton)H2BC1
Genetics Home Reference (NIH)H2BC1
Genomic and cartography
GoldenPath hg38 (UCSC)H2BC1  -  
GoldenPath hg19 (UCSC)H2BC1  -  
GoldenPathH2BC1 - [CytoView hg19]  H2BC1 - [CytoView hg38]
ImmunoBaseENSG00000146047
Mapping of homologs : NCBIH2BC1 [Mapview hg19]  H2BC1 [Mapview hg38]
OMIM609904   
Gene and transcription
Genbank (Entrez)AK312055 BC066238 BC066239 BC066240 BC066241
RefSeq transcript (Entrez)NM_170610
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H2BC1
Cluster EST : UnigeneHs.591786 [ NCBI ]
CGAP (NCI)Hs.591786
Alternative Splicing GalleryENSG00000146047
Gene ExpressionH2BC1 [ NCBI-GEO ]   H2BC1 [ EBI - ARRAY_EXPRESS ]   H2BC1 [ SEEK ]   H2BC1 [ MEM ]
Gene Expression Viewer (FireBrowse)H2BC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255626
GTEX Portal (Tissue expression)H2BC1
Human Protein AtlasENSG00000146047-H2BC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96A08   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96A08  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96A08
Splice isoforms : SwissVarQ96A08
PhosPhoSitePlusQ96A08
Domaine pattern : Prosite (Expaxy)HISTONE_H2B (PS00357)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H2B   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H2B (SM00427)  
Conserved Domain (NCBI)H2BC1
DMDM Disease mutations255626
Blocks (Seattle)H2BC1
PDB (RSDB)3WKJ    5GSU    5GT3   
PDB Europe3WKJ    5GSU    5GT3   
PDB (PDBSum)3WKJ    5GSU    5GT3   
PDB (IMB)3WKJ    5GSU    5GT3   
Structural Biology KnowledgeBase3WKJ    5GSU    5GT3   
SCOP (Structural Classification of Proteins)3WKJ    5GSU    5GT3   
CATH (Classification of proteins structures)3WKJ    5GSU    5GT3   
SuperfamilyQ96A08
Human Protein Atlas [tissue]ENSG00000146047-H2BC1 [tissue]
Peptide AtlasQ96A08
IPIIPI00465363   
Protein Interaction databases
DIP (DOE-UCLA)Q96A08
IntAct (EBI)Q96A08
FunCoupENSG00000146047
BioGRIDH2BC1
STRING (EMBL)H2BC1
ZODIACH2BC1
Ontologies - Pathways
QuickGOQ96A08
Ontology : AmiGOnuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  molecular_function  DNA binding  nucleus  nucleoplasm  nucleosome assembly  nucleosome assembly  nucleosome assembly  nucleosome disassembly  inflammatory response  protein ubiquitination  extrinsic component of plasma membrane  plasminogen activation  spermatogenesis, exchange of chromosomal proteins  histone binding  protein heterodimerization activity  positive regulation of binding  mononuclear cell migration  
Ontology : EGO-EBInuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  molecular_function  DNA binding  nucleus  nucleoplasm  nucleosome assembly  nucleosome assembly  nucleosome assembly  nucleosome disassembly  inflammatory response  protein ubiquitination  extrinsic component of plasma membrane  plasminogen activation  spermatogenesis, exchange of chromosomal proteins  histone binding  protein heterodimerization activity  positive regulation of binding  mononuclear cell migration  
NDEx NetworkH2BC1
Atlas of Cancer Signalling NetworkH2BC1
Wikipedia pathwaysH2BC1
Orthology - Evolution
OrthoDB255626
GeneTree (enSembl)ENSG00000146047
Phylogenetic Trees/Animal Genes : TreeFamH2BC1
HOGENOMQ96A08
Homologs : HomoloGeneH2BC1
Homology/Alignments : Family Browser (UCSC)H2BC1
Gene fusions - Rearrangements
Fusion : QuiverH2BC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH2BC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H2BC1
dbVarH2BC1
ClinVarH2BC1
1000_GenomesH2BC1 
Exome Variant ServerH2BC1
ExAC (Exome Aggregation Consortium)ENSG00000146047
GNOMAD BrowserENSG00000146047
Varsome BrowserH2BC1
Genetic variants : HAPMAP255626
Genomic Variants (DGV)H2BC1 [DGVbeta]
DECIPHERH2BC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH2BC1 
Mutations
ICGC Data PortalH2BC1 
TCGA Data PortalH2BC1 
Broad Tumor PortalH2BC1
OASIS PortalH2BC1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH2BC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H2BC1
DgiDB (Drug Gene Interaction Database)H2BC1
DoCM (Curated mutations)H2BC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H2BC1 (select a term)
intoGenH2BC1
Cancer3DH2BC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609904   
Orphanet
DisGeNETH2BC1
MedgenH2BC1
Genetic Testing Registry H2BC1
NextProtQ96A08 [Medical]
TSGene255626
GENETestsH2BC1
Target ValidationH2BC1
Huge Navigator H2BC1 [HugePedia]
snp3D : Map Gene to Disease255626
BioCentury BCIQH2BC1
ClinGenH2BC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD255626
Chemical/Pharm GKB GenePA134937673
Clinical trialH2BC1
Miscellaneous
canSAR (ICR)H2BC1 (select the gene name)
DataMed IndexH2BC1
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH2BC1
EVEXH2BC1
GoPubMedH2BC1
iHOPH2BC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:46:06 CET 2019

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