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H3-4 (H3.4 histone)

Identity

Alias_namesH3FT
HIST3H3
H3 histone family, member T
histone 3, H3
histone cluster 3, H3
histone cluster 3 H3
Alias_symbol (synonym)H3t
H3/g
H3.4
Other alias
HGNC (Hugo) H3-4
LocusID (NCBI) 8290
Atlas_Id 58148
Location 1q42.13  [Link to chromosome band 1q42]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H3-4   4778
Cards
Entrez_Gene (NCBI)H3-4  8290  H3.4 histone
AliasesH3.4; H3/g; H3FT; H3t; 
HIST3H3
GeneCards (Weizmann)H3-4
Ensembl hg19 (Hinxton)ENSG00000168148 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168148 [Gene_View]  ENSG00000168148 [Sequence]  - [Contig_View]  H3-4 [Vega]
ICGC DataPortalENSG00000168148
TCGA cBioPortalH3-4
AceView (NCBI)H3-4
Genatlas (Paris)H3-4
WikiGenes8290
SOURCE (Princeton)H3-4
Genetics Home Reference (NIH)H3-4
Genomic and cartography
GoldenPath hg38 (UCSC)H3-4  -  
GoldenPath hg19 (UCSC)H3-4  -  
GoldenPathH3-4 - [CytoView hg19]  H3-4 - [CytoView hg38]
ImmunoBaseENSG00000168148
Mapping of homologs : NCBIH3-4 [Mapview hg19]  H3-4 [Mapview hg38]
OMIM602820   
Gene and transcription
Genbank (Entrez)AK312217 BC069079 BC101837 BC101839 CR542013
RefSeq transcript (Entrez)NM_003493
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H3-4
Cluster EST : UnigeneHs.248171 [ NCBI ]
CGAP (NCI)Hs.248171
Alternative Splicing GalleryENSG00000168148
Gene ExpressionH3-4 [ NCBI-GEO ]   H3-4 [ EBI - ARRAY_EXPRESS ]   H3-4 [ SEEK ]   H3-4 [ MEM ]
Gene Expression Viewer (FireBrowse)H3-4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8290
GTEX Portal (Tissue expression)H3-4
Human Protein AtlasENSG00000168148-H3-4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16695   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16695  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16695
Splice isoforms : SwissVarQ16695
PhosPhoSitePlusQ16695
Domaine pattern : Prosite (Expaxy)HISTONE_H3_1 (PS00322)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H3/CENP-A   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H3 (SM00428)  
Conserved Domain (NCBI)H3-4
DMDM Disease mutations8290
Blocks (Seattle)H3-4
PDB (RSDB)2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
PDB Europe2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
PDB (PDBSum)2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
PDB (IMB)2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
Structural Biology KnowledgeBase2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
SCOP (Structural Classification of Proteins)2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
CATH (Classification of proteins structures)2V1D    2YBP    2YBS    3A6N    3T6R    4V2V    4V2W   
SuperfamilyQ16695
Human Protein Atlas [tissue]ENSG00000168148-H3-4 [tissue]
Peptide AtlasQ16695
IPIIPI00216402   
Protein Interaction databases
DIP (DOE-UCLA)Q16695
IntAct (EBI)Q16695
FunCoupENSG00000168148
BioGRIDH3-4
STRING (EMBL)H3-4
ZODIACH3-4
Ontologies - Pathways
QuickGOQ16695
Ontology : AmiGOnuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  protein binding  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  telomere capping  nucleosomal DNA binding  negative regulation of protein oligomerization  protein heterodimerization activity  protein heterotetramerization  extracellular exosome  
Ontology : EGO-EBInuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  protein binding  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  telomere capping  nucleosomal DNA binding  negative regulation of protein oligomerization  protein heterodimerization activity  protein heterotetramerization  extracellular exosome  
NDEx NetworkH3-4
Atlas of Cancer Signalling NetworkH3-4
Wikipedia pathwaysH3-4
Orthology - Evolution
OrthoDB8290
GeneTree (enSembl)ENSG00000168148
Phylogenetic Trees/Animal Genes : TreeFamH3-4
HOGENOMQ16695
Homologs : HomoloGeneH3-4
Homology/Alignments : Family Browser (UCSC)H3-4
Gene fusions - Rearrangements
Fusion : QuiverH3-4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH3-4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H3-4
dbVarH3-4
ClinVarH3-4
1000_GenomesH3-4 
Exome Variant ServerH3-4
ExAC (Exome Aggregation Consortium)ENSG00000168148
GNOMAD BrowserENSG00000168148
Varsome BrowserH3-4
Genetic variants : HAPMAP8290
Genomic Variants (DGV)H3-4 [DGVbeta]
DECIPHERH3-4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH3-4 
Mutations
ICGC Data PortalH3-4 
TCGA Data PortalH3-4 
Broad Tumor PortalH3-4
OASIS PortalH3-4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH3-4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H3-4
DgiDB (Drug Gene Interaction Database)H3-4
DoCM (Curated mutations)H3-4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H3-4 (select a term)
intoGenH3-4
Cancer3DH3-4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602820   
Orphanet
DisGeNETH3-4
MedgenH3-4
Genetic Testing Registry H3-4
NextProtQ16695 [Medical]
TSGene8290
GENETestsH3-4
Target ValidationH3-4
Huge Navigator H3-4 [HugePedia]
snp3D : Map Gene to Disease8290
BioCentury BCIQH3-4
ClinGenH3-4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8290
Chemical/Pharm GKB GenePA29153
Clinical trialH3-4
Miscellaneous
canSAR (ICR)H3-4 (select the gene name)
DataMed IndexH3-4
Probes
Litterature
PubMed277 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH3-4
EVEXH3-4
GoPubMedH3-4
iHOPH3-4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:46:07 CET 2019

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