Atlas of Genetics and Cytogenetics in Oncology and Haematology


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H3C15 (H3 clustered histone 15)

Identity

Alias_namesHIST2H3A
histone 2, H3a
histone cluster 2, H3a
histone cluster 2 H3 family member a
Alias_symbol (synonym)H3/n
H3/o
Other alias
HGNC (Hugo) H3C15
LocusID (NCBI) 333932
Atlas_Id 58056
Location 1q21.2  [Link to chromosome band 1q21]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)H3C15   20505
Cards
Entrez_Gene (NCBI)H3C15  333932  H3 clustered histone 15
AliasesH3/n; H3/o; HIST2H3A
GeneCards (Weizmann)H3C15
Ensembl hg19 (Hinxton)ENSG00000203852 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000203852 [Gene_View]  ENSG00000203852 [Sequence]  - [Contig_View]  H3C15 [Vega]
ICGC DataPortalENSG00000203852
TCGA cBioPortalH3C15
AceView (NCBI)H3C15
Genatlas (Paris)H3C15
WikiGenes333932
SOURCE (Princeton)H3C15
Genetics Home Reference (NIH)H3C15
Genomic and cartography
GoldenPath hg38 (UCSC)H3C15  -  
GoldenPath hg19 (UCSC)H3C15  -  
GoldenPathH3C15 - [CytoView hg19]  H3C15 - [CytoView hg38]
ImmunoBaseENSG00000203852
Mapping of homologs : NCBIH3C15 [Mapview hg19]  H3C15 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC015544 BC074969 BC130635 BC130637
RefSeq transcript (Entrez)NM_001005464
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H3C15
Cluster EST : UnigeneHs.706618 [ NCBI ]
CGAP (NCI)Hs.706618
Alternative Splicing GalleryENSG00000203852
Gene ExpressionH3C15 [ NCBI-GEO ]   H3C15 [ EBI - ARRAY_EXPRESS ]   H3C15 [ SEEK ]   H3C15 [ MEM ]
Gene Expression Viewer (FireBrowse)H3C15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)333932
GTEX Portal (Tissue expression)H3C15
Human Protein AtlasENSG00000203852-H3C15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ71DI3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ71DI3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ71DI3
Splice isoforms : SwissVarQ71DI3
PhosPhoSitePlusQ71DI3
Domaine pattern : Prosite (Expaxy)HISTONE_H3_1 (PS00322)    HISTONE_H3_2 (PS00959)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H3/CENP-A   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H3 (SM00428)  
Conserved Domain (NCBI)H3C15
DMDM Disease mutations333932
Blocks (Seattle)H3C15
PDB (RSDB)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
PDB Europe2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
PDB (PDBSum)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
PDB (IMB)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
Structural Biology KnowledgeBase2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
SCOP (Structural Classification of Proteins)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
CATH (Classification of proteins structures)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU    5VAC   
SuperfamilyQ71DI3
Human Protein Atlas [tissue]ENSG00000203852-H3C15 [tissue]
Peptide AtlasQ71DI3
Protein Interaction databases
DIP (DOE-UCLA)Q71DI3
IntAct (EBI)Q71DI3
FunCoupENSG00000203852
BioGRIDH3C15
STRING (EMBL)H3C15
ZODIACH3C15
Ontologies - Pathways
QuickGOQ71DI3
Ontology : AmiGOchromatin silencing at rDNA  nucleosome  nucleosome  protein binding  extracellular region  nucleus  nucleus  nucleus  nucleoplasm  chromatin organization  nucleosome assembly  blood coagulation  nucleosomal DNA binding  interleukin-7-mediated signaling pathway  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  protein heterodimerization activity  regulation of gene silencing by miRNA  extracellular exosome  
Ontology : EGO-EBIchromatin silencing at rDNA  nucleosome  nucleosome  protein binding  extracellular region  nucleus  nucleus  nucleus  nucleoplasm  chromatin organization  nucleosome assembly  blood coagulation  nucleosomal DNA binding  interleukin-7-mediated signaling pathway  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  protein heterodimerization activity  regulation of gene silencing by miRNA  extracellular exosome  
NDEx NetworkH3C15
Atlas of Cancer Signalling NetworkH3C15
Wikipedia pathwaysH3C15
Orthology - Evolution
OrthoDB333932
GeneTree (enSembl)ENSG00000203852
Phylogenetic Trees/Animal Genes : TreeFamH3C15
HOGENOMQ71DI3
Homologs : HomoloGeneH3C15
Homology/Alignments : Family Browser (UCSC)H3C15
Gene fusions - Rearrangements
Fusion : QuiverH3C15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH3C15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H3C15
dbVarH3C15
ClinVarH3C15
1000_GenomesH3C15 
Exome Variant ServerH3C15
ExAC (Exome Aggregation Consortium)ENSG00000203852
GNOMAD BrowserENSG00000203852
Varsome BrowserH3C15
Genetic variants : HAPMAP333932
Genomic Variants (DGV)H3C15 [DGVbeta]
DECIPHERH3C15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH3C15 
Mutations
ICGC Data PortalH3C15 
TCGA Data PortalH3C15 
Broad Tumor PortalH3C15
OASIS PortalH3C15 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDH3C15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H3C15
DgiDB (Drug Gene Interaction Database)H3C15
DoCM (Curated mutations)H3C15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H3C15 (select a term)
intoGenH3C15
Cancer3DH3C15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETH3C15
MedgenH3C15
Genetic Testing Registry H3C15
NextProtQ71DI3 [Medical]
TSGene333932
GENETestsH3C15
Target ValidationH3C15
Huge Navigator H3C15 [HugePedia]
snp3D : Map Gene to Disease333932
BioCentury BCIQH3C15
ClinGenH3C15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD333932
Chemical/Pharm GKB GenePA134926636
Clinical trialH3C15
Miscellaneous
canSAR (ICR)H3C15 (select the gene name)
DataMed IndexH3C15
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH3C15
EVEXH3C15
GoPubMedH3C15
iHOPH3C15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:46:08 CET 2019

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