Atlas of Genetics and Cytogenetics in Oncology and Haematology


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H3F3B (H3 histone family member 3B)

Identity

Alias_namesH3 histone, family 3B (H3.3B)
H3 histone, family 3B
Alias_symbol (synonym)H3.3B
Other alias
HGNC (Hugo) H3F3B
LocusID (NCBI) 3021
Atlas_Id 53818
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75776434 and ends at 75779935 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
H3F3B (17q25.1) / KCTD18 (2q33.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)H3F3B   4765
Cards
Entrez_Gene (NCBI)H3F3B  3021  H3 histone family member 3B
AliasesH3.3B
GeneCards (Weizmann)H3F3B
Ensembl hg19 (Hinxton)ENSG00000132475 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132475 [Gene_View]  chr17:75776434-75779935 [Contig_View]  H3F3B [Vega]
ICGC DataPortalENSG00000132475
TCGA cBioPortalH3F3B
AceView (NCBI)H3F3B
Genatlas (Paris)H3F3B
WikiGenes3021
SOURCE (Princeton)H3F3B
Genetics Home Reference (NIH)H3F3B
Genomic and cartography
GoldenPath hg38 (UCSC)H3F3B  -     chr17:75776434-75779935 -  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)H3F3B  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblH3F3B - 17q25.1 [CytoView hg19]  H3F3B - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIH3F3B [Mapview hg19]  H3F3B [Mapview hg38]
OMIM601058   
Gene and transcription
Genbank (Entrez)AF218029 AK054591 AK130772 AK304607 AK312762
RefSeq transcript (Entrez)NM_005324
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)H3F3B
Cluster EST : UnigeneHs.180877 [ NCBI ]
CGAP (NCI)Hs.180877
Alternative Splicing GalleryENSG00000132475
Gene ExpressionH3F3B [ NCBI-GEO ]   H3F3B [ EBI - ARRAY_EXPRESS ]   H3F3B [ SEEK ]   H3F3B [ MEM ]
Gene Expression Viewer (FireBrowse)H3F3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3021
GTEX Portal (Tissue expression)H3F3B
Human Protein AtlasENSG00000132475-H3F3B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP84243   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP84243  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP84243
Splice isoforms : SwissVarP84243
PhosPhoSitePlusP84243
Domaine pattern : Prosite (Expaxy)HISTONE_H3_1 (PS00322)    HISTONE_H3_2 (PS00959)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H3/CENP-A   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H3 (SM00428)  
Conserved Domain (NCBI)H3F3B
DMDM Disease mutations3021
Blocks (Seattle)H3F3B
PDB (SRS)2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
PDB (PDBSum)2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
PDB (IMB)2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
PDB (RSDB)2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
Structural Biology KnowledgeBase2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
SCOP (Structural Classification of Proteins)2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
CATH (Classification of proteins structures)2L43    3ASK    3ASL    3AV2    3JVK    3MUK    3MUL    3QL9    3QLA    3QLC    3WTP    4GNE    4GNF    4GNG    4GU0    4GUR    4GUS    4GY5    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4L58    4N4I    4O62    4QQ4    4TMP    4U7T    4W5A    5AY8    5B32    5B33    5BNV    5BNX    5DWQ    5DX0    5JA4    5JJY    5JLB    5KDM   
SuperfamilyP84243
Human Protein Atlas [tissue]ENSG00000132475-H3F3B [tissue]
Peptide AtlasP84243
HPRD03036
Protein Interaction databases
DIP (DOE-UCLA)P84243
IntAct (EBI)P84243
FunCoupENSG00000132475
BioGRIDH3F3B
STRING (EMBL)H3F3B
ZODIACH3F3B
Ontologies - Pathways
QuickGOP84243
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nuclear nucleosome  RNA polymerase II core promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  osteoblast differentiation  Barr body  protein binding  extracellular region  nucleus  nucleoplasm  nucleosome assembly  nucleosome assembly  DNA replication-independent nucleosome assembly  nucleus organization  spermatid development  single fertilization  brain development  embryo implantation  blood coagulation  cell proliferation  male gonad development  response to hormone  positive regulation of cell growth  gene silencing by RNA  nucleosomal DNA binding  pericentric heterochromatin assembly  telomeric heterochromatin assembly  telomere organization  multicellular organism growth  histone binding  muscle cell differentiation  protein complex  cellular protein metabolic process  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  oogenesis  extracellular exosome  regulation of centromere complex assembly  negative regulation of chromosome condensation  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nuclear nucleosome  RNA polymerase II core promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  osteoblast differentiation  Barr body  protein binding  extracellular region  nucleus  nucleoplasm  nucleosome assembly  nucleosome assembly  DNA replication-independent nucleosome assembly  nucleus organization  spermatid development  single fertilization  brain development  embryo implantation  blood coagulation  cell proliferation  male gonad development  response to hormone  positive regulation of cell growth  gene silencing by RNA  nucleosomal DNA binding  pericentric heterochromatin assembly  telomeric heterochromatin assembly  telomere organization  multicellular organism growth  histone binding  muscle cell differentiation  protein complex  cellular protein metabolic process  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  oogenesis  extracellular exosome  regulation of centromere complex assembly  negative regulation of chromosome condensation  
Pathways : KEGGAlcoholism    Transcriptional misregulation in cancer    Systemic lupus erythematosus   
NDEx NetworkH3F3B
Atlas of Cancer Signalling NetworkH3F3B
Wikipedia pathwaysH3F3B
Orthology - Evolution
OrthoDB3021
GeneTree (enSembl)ENSG00000132475
Phylogenetic Trees/Animal Genes : TreeFamH3F3B
HOVERGENP84243
HOGENOMP84243
Homologs : HomoloGeneH3F3B
Homology/Alignments : Family Browser (UCSC)H3F3B
Gene fusions - Rearrangements
Fusion: Tumor Portal H3F3B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerH3F3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)H3F3B
dbVarH3F3B
ClinVarH3F3B
1000_GenomesH3F3B 
Exome Variant ServerH3F3B
ExAC (Exome Aggregation Consortium)ENSG00000132475
GNOMAD BrowserENSG00000132475
Genetic variants : HAPMAP3021
Genomic Variants (DGV)H3F3B [DGVbeta]
DECIPHERH3F3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisH3F3B 
Mutations
ICGC Data PortalH3F3B 
TCGA Data PortalH3F3B 
Broad Tumor PortalH3F3B
OASIS PortalH3F3B [ Somatic mutations - Copy number]
Cancer Gene: CensusH3F3B 
Somatic Mutations in Cancer : COSMICH3F3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDH3F3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch H3F3B
DgiDB (Drug Gene Interaction Database)H3F3B
DoCM (Curated mutations)H3F3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)H3F3B (select a term)
intoGenH3F3B
Cancer3DH3F3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601058   
Orphanet
MedgenH3F3B
Genetic Testing Registry H3F3B
NextProtP84243 [Medical]
TSGene3021
GENETestsH3F3B
Target ValidationH3F3B
Huge Navigator H3F3B [HugePedia]
snp3D : Map Gene to Disease3021
BioCentury BCIQH3F3B
ClinGenH3F3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3021
Chemical/Pharm GKB GenePA29140
Clinical trialH3F3B
Miscellaneous
canSAR (ICR)H3F3B (select the gene name)
Probes
Litterature
PubMed63 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineH3F3B
EVEXH3F3B
GoPubMedH3F3B
iHOPH3F3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:52:18 CET 2017

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