Atlas of Genetics and Cytogenetics in Oncology and Haematology

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HABP2 (hyaluronan binding protein 2)

Identity

Alias_nameshyaluronan-binding protein 2
Alias_symbol (synonym)HABP
PHBP
HGFAL
FSAP
Other aliasNMTC5
HGNC (Hugo) HABP2
LocusID (NCBI) 3026
Atlas_Id 55332
Location 10q25.3  [Link to chromosome band 10q25]
Location_base_pair Starts at 113552978 and ends at 113589601 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)HABP2   4798
Cards
Entrez_Gene (NCBI)HABP2  3026  hyaluronan binding protein 2
AliasesFSAP; HABP; HGFAL; NMTC5; 
PHBP
GeneCards (Weizmann)HABP2
Ensembl hg19 (Hinxton)ENSG00000148702 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148702 [Gene_View]  ENSG00000148702 [Sequence]  chr10:113552978-113589601 [Contig_View]  HABP2 [Vega]
ICGC DataPortalENSG00000148702
TCGA cBioPortalHABP2
AceView (NCBI)HABP2
Genatlas (Paris)HABP2
WikiGenes3026
SOURCE (Princeton)HABP2
Genetics Home Reference (NIH)HABP2
Genomic and cartography
GoldenPath hg38 (UCSC)HABP2  -     chr10:113552978-113589601 +  10q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HABP2  -     10q25.3   [Description]    (hg19-Feb_2009)
EnsemblHABP2 - 10q25.3 [CytoView hg19]  HABP2 - 10q25.3 [CytoView hg38]
Mapping of homologs : NCBIHABP2 [Mapview hg19]  HABP2 [Mapview hg38]
OMIM188050   603924   616535   
Gene and transcription
Genbank (Entrez)AA484932 AI373912 AK290832 AK303759 AK303761
RefSeq transcript (Entrez)NM_001177660 NM_004132
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HABP2
Cluster EST : UnigeneHs.422542 [ NCBI ]
CGAP (NCI)Hs.422542
Alternative Splicing GalleryENSG00000148702
Gene ExpressionHABP2 [ NCBI-GEO ]   HABP2 [ EBI - ARRAY_EXPRESS ]   HABP2 [ SEEK ]   HABP2 [ MEM ]
Gene Expression Viewer (FireBrowse)HABP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3026
GTEX Portal (Tissue expression)HABP2
Human Protein AtlasENSG00000148702-HABP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14520   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14520  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14520
Splice isoforms : SwissVarQ14520
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ14520
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    KRINGLE_1 (PS00021)    KRINGLE_2 (PS50070)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    Kringle    Kringle-like    Kringle_CS    Kringle_sf    Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)EGF (PF00008)    Kringle (PF00051)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00008    pfam00051    pfam00089   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  KR (SM00130)  Tryp_SPc (SM00020)  
Conserved Domain (NCBI)HABP2
DMDM Disease mutations3026
Blocks (Seattle)HABP2
SuperfamilyQ14520
Human Protein Atlas [tissue]ENSG00000148702-HABP2 [tissue]
Peptide AtlasQ14520
HPRD04890
IPIIPI00746623   IPI01009177   IPI00922719   IPI00964994   
Protein Interaction databases
DIP (DOE-UCLA)Q14520
IntAct (EBI)Q14520
FunCoupENSG00000148702
BioGRIDHABP2
STRING (EMBL)HABP2
ZODIACHABP2
Ontologies - Pathways
QuickGOQ14520
Ontology : AmiGOserine-type endopeptidase activity  calcium ion binding  glycosaminoglycan binding  extracellular region  extracellular space  proteolysis  cell adhesion  
Ontology : EGO-EBIserine-type endopeptidase activity  calcium ion binding  glycosaminoglycan binding  extracellular region  extracellular space  proteolysis  cell adhesion  
NDEx NetworkHABP2
Atlas of Cancer Signalling NetworkHABP2
Wikipedia pathwaysHABP2
Orthology - Evolution
OrthoDB3026
GeneTree (enSembl)ENSG00000148702
Phylogenetic Trees/Animal Genes : TreeFamHABP2
HOGENOMQ14520
Homologs : HomoloGeneHABP2
Homology/Alignments : Family Browser (UCSC)HABP2
Gene fusions - Rearrangements
Fusion : QuiverHABP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHABP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HABP2
dbVarHABP2
ClinVarHABP2
1000_GenomesHABP2 
Exome Variant ServerHABP2
ExAC (Exome Aggregation Consortium)ENSG00000148702
GNOMAD BrowserENSG00000148702
Varsome BrowserHABP2
Genetic variants : HAPMAP3026
Genomic Variants (DGV)HABP2 [DGVbeta]
DECIPHERHABP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHABP2 
Mutations
ICGC Data PortalHABP2 
TCGA Data PortalHABP2 
Broad Tumor PortalHABP2
OASIS PortalHABP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHABP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHABP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HABP2
DgiDB (Drug Gene Interaction Database)HABP2
DoCM (Curated mutations)HABP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HABP2 (select a term)
intoGenHABP2
Cancer3DHABP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM188050    603924    616535   
Orphanet21661   
DisGeNETHABP2
MedgenHABP2
Genetic Testing Registry HABP2
NextProtQ14520 [Medical]
TSGene3026
GENETestsHABP2
Target ValidationHABP2
Huge Navigator HABP2 [HugePedia]
snp3D : Map Gene to Disease3026
BioCentury BCIQHABP2
ClinGenHABP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3026
Chemical/Pharm GKB GenePA29172
Clinical trialHABP2
Miscellaneous
canSAR (ICR)HABP2 (select the gene name)
DataMed IndexHABP2
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHABP2
EVEXHABP2
GoPubMedHABP2
iHOPHABP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Feb 14 16:33:36 CET 2019
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