HACD4 (3-hydroxyacyl-CoA dehydratase 4)

2014-05-01  

Identity

HGNC
LOCATION
9p21.3
LOCUSID
ALIAS
PTPLAD2
FUSION GENES

Other Information

Locus ID:

NCBI: 401494
MIM: 615941
HGNC: 20920
Ensembl: ENSG00000188921

Variants:

dbSNP: 401494
ClinVar: 401494
TCGA: ENSG00000188921
COSMIC: HACD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188921ENST00000495827Q5VWC8

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Fatty acid elongationKEGGko00062
Biosynthesis of unsaturated fatty acidsKEGGko01040
Fatty acid elongationKEGGhsa00062
Biosynthesis of unsaturated fatty acidsKEGGhsa01040
Fatty acid biosynthesis, elongation, endoplasmic reticulumKEGGhsa_M00415
Fatty acid biosynthesis, elongation, endoplasmic reticulumKEGGM00415
Fatty acid metabolismKEGGhsa01212
Fatty acid metabolismKEGGko01212
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Fatty Acyl-CoA BiosynthesisREACTOMER-HSA-75105
Synthesis of very long-chain fatty acyl-CoAsREACTOMER-HSA-75876

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
245306852014PTPLAD2 is a tumor suppressor in esophageal squamous cell carcinogenesis.0
290317762018The HACD4 haplotype as a risk factor for atherosclerosis in males.0

Citation

Dessen P

HACD4 (3-hydroxyacyl-CoA dehydratase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53913/hacd4