Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HAO1 (hydroxyacid oxidase 1)

Identity

Alias_namesGOX1
hydroxyacid oxidase (glycolate oxidase) 1
Alias_symbol (synonym)GOX
Other aliasHAOX1
HGNC (Hugo) HAO1
LocusID (NCBI) 54363
Atlas_Id 64167
Location 20p12.3  [Link to chromosome band 20p12]
Location_base_pair Starts at 7882984 and ends at 7940446 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HAO1   4809
Cards
Entrez_Gene (NCBI)HAO1  54363  hydroxyacid oxidase 1
AliasesGOX; GOX1; HAOX1
GeneCards (Weizmann)HAO1
Ensembl hg19 (Hinxton)ENSG00000101323 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101323 [Gene_View]  chr20:7882984-7940446 [Contig_View]  HAO1 [Vega]
ICGC DataPortalENSG00000101323
TCGA cBioPortalHAO1
AceView (NCBI)HAO1
Genatlas (Paris)HAO1
WikiGenes54363
SOURCE (Princeton)HAO1
Genetics Home Reference (NIH)HAO1
Genomic and cartography
GoldenPath hg38 (UCSC)HAO1  -     chr20:7882984-7940446 -  20p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HAO1  -     20p12.3   [Description]    (hg19-Feb_2009)
EnsemblHAO1 - 20p12.3 [CytoView hg19]  HAO1 - 20p12.3 [CytoView hg38]
Mapping of homologs : NCBIHAO1 [Mapview hg19]  HAO1 [Mapview hg38]
OMIM605023   
Gene and transcription
Genbank (Entrez)AB024079 AF231916 AF244134 AK289423 AK308963
RefSeq transcript (Entrez)NM_017545
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HAO1
Cluster EST : UnigeneHs.193640 [ NCBI ]
CGAP (NCI)Hs.193640
Alternative Splicing GalleryENSG00000101323
Gene ExpressionHAO1 [ NCBI-GEO ]   HAO1 [ EBI - ARRAY_EXPRESS ]   HAO1 [ SEEK ]   HAO1 [ MEM ]
Gene Expression Viewer (FireBrowse)HAO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54363
GTEX Portal (Tissue expression)HAO1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJM8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJM8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJM8
Splice isoforms : SwissVarQ9UJM8
Catalytic activity : Enzyme1.1.3.15 [ Enzyme-Expasy ]   1.1.3.151.1.3.15 [ IntEnz-EBI ]   1.1.3.15 [ BRENDA ]   1.1.3.15 [ KEGG ]   
PhosPhoSitePlusQ9UJM8
Domaine pattern : Prosite (Expaxy)FMN_HYDROXY_ACID_DH_1 (PS00557)    FMN_HYDROXY_ACID_DH_2 (PS51349)   
Domains : Interpro (EBI)Aldolase_TIM    Alpha-hydoxy_acid_DH_FMN    FMN-dep_DH    FMN_hydac_DH_AS   
Domain families : Pfam (Sanger)FMN_dh (PF01070)   
Domain families : Pfam (NCBI)pfam01070   
Conserved Domain (NCBI)HAO1
DMDM Disease mutations54363
Blocks (Seattle)HAO1
PDB (SRS)2NZL    2RDT    2RDU    2RDW    2W0U   
PDB (PDBSum)2NZL    2RDT    2RDU    2RDW    2W0U   
PDB (IMB)2NZL    2RDT    2RDU    2RDW    2W0U   
PDB (RSDB)2NZL    2RDT    2RDU    2RDW    2W0U   
Structural Biology KnowledgeBase2NZL    2RDT    2RDU    2RDW    2W0U   
SCOP (Structural Classification of Proteins)2NZL    2RDT    2RDU    2RDW    2W0U   
CATH (Classification of proteins structures)2NZL    2RDT    2RDU    2RDW    2W0U   
SuperfamilyQ9UJM8
Human Protein AtlasENSG00000101323
Peptide AtlasQ9UJM8
HPRD05429
IPIIPI00006934   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJM8
IntAct (EBI)Q9UJM8
FunCoupENSG00000101323
BioGRIDHAO1
STRING (EMBL)HAO1
ZODIACHAO1
Ontologies - Pathways
QuickGOQ9UJM8
Ontology : AmiGOfatty acid alpha-oxidation  (S)-2-hydroxy-acid oxidase activity  receptor binding  peroxisome  peroxisomal matrix  response to oxidative stress  glycolate oxidase activity  glycolate oxidase activity  FMN binding  glycolate catabolic process  glycolate catabolic process  glyoxylate metabolic process  glyoxylate oxidase activity  very-long-chain-(S)-2-hydroxy-acid oxidase activity  long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity  medium-chain-(S)-2-hydroxy-acid oxidase activity  
Ontology : EGO-EBIfatty acid alpha-oxidation  (S)-2-hydroxy-acid oxidase activity  receptor binding  peroxisome  peroxisomal matrix  response to oxidative stress  glycolate oxidase activity  glycolate oxidase activity  FMN binding  glycolate catabolic process  glycolate catabolic process  glyoxylate metabolic process  glyoxylate oxidase activity  very-long-chain-(S)-2-hydroxy-acid oxidase activity  long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity  medium-chain-(S)-2-hydroxy-acid oxidase activity  
Pathways : KEGGGlyoxylate and dicarboxylate metabolism    Peroxisome   
NDEx NetworkHAO1
Atlas of Cancer Signalling NetworkHAO1
Wikipedia pathwaysHAO1
Orthology - Evolution
OrthoDB54363
GeneTree (enSembl)ENSG00000101323
Phylogenetic Trees/Animal Genes : TreeFamHAO1
HOVERGENQ9UJM8
HOGENOMQ9UJM8
Homologs : HomoloGeneHAO1
Homology/Alignments : Family Browser (UCSC)HAO1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHAO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HAO1
dbVarHAO1
ClinVarHAO1
1000_GenomesHAO1 
Exome Variant ServerHAO1
ExAC (Exome Aggregation Consortium)HAO1 (select the gene name)
Genetic variants : HAPMAP54363
Genomic Variants (DGV)HAO1 [DGVbeta]
DECIPHERHAO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHAO1 
Mutations
ICGC Data PortalHAO1 
TCGA Data PortalHAO1 
Broad Tumor PortalHAO1
OASIS PortalHAO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHAO1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHAO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HAO1
DgiDB (Drug Gene Interaction Database)HAO1
DoCM (Curated mutations)HAO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HAO1 (select a term)
intoGenHAO1
Cancer3DHAO1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605023   
Orphanet
MedgenHAO1
Genetic Testing Registry HAO1
NextProtQ9UJM8 [Medical]
TSGene54363
GENETestsHAO1
Target ValidationHAO1
Huge Navigator HAO1 [HugePedia]
snp3D : Map Gene to Disease54363
BioCentury BCIQHAO1
ClinGenHAO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54363
Chemical/Pharm GKB GenePA29185
Clinical trialHAO1
Miscellaneous
canSAR (ICR)HAO1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHAO1
EVEXHAO1
GoPubMedHAO1
iHOPHAO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:10:13 CEST 2017

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