HASPIN (histone H3 associated protein kinase)

2017-09-01 Affiliation

HGNC

HASPIN

LOCATION

17p13.2

LOCUSID

83903

ALIAS

GSG2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 83903
ClinVar: 83903
TCGA: ENSG00000177602
COSMIC: HASPIN

Gene ID	Transcript ID	Uniprot
ENSG00000177602	ENST00000325418	Q8TF76

Not detected

Low

Medium

High

Pubmed ID	Year	Title	Citations
20929775	2010	Two histone marks establish the inner centromere and chromosome bi-orientation.	185
20705812	2010	Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.	183
15681610	2005	The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.	131
17084365	2006	Regulation of mitotic chromosome cohesion by Haspin and Aurora B.	78
21658950	2011	A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosis.	61
23071152	2012	Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.	42
19910498	2009	Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion.	28
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	27
25854549	2015	Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores.	22
19997740	2010	Haspin: a newly discovered regulator of mitotic chromosome behavior.	20

Dessen P

HASPIN (histone H3 associated protein kinase)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01