HAVCR1 (hepatitis A virus cellular receptor 1)

2003-12-01  

Identity

HGNC
HAVCR1
LOCATION
5q33.3
LOCUSID
26762
ALIAS
CD365,HAVCR,HAVCR-1,KIM-1,KIM1,TIM,TIM-1,TIM1,TIMD-1,TIMD1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26762
MIM: 606518
HGNC: 17866
Ensembl: ENSG00000113249

Variants:

dbSNP: 26762
ClinVar: 26762
TCGA: ENSG00000113249
COSMIC: HAVCR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113249ENST00000339252Q96D42
ENSG00000113249ENST00000518745E5RIF6
ENSG00000113249ENST00000522693E9PFX0
ENSG00000113249ENST00000523175Q96D42
ENSG00000113249ENST00000625904E9PFX0

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
180824332007TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.246
215368712011T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus.150
117253012001Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family.137
177034122007Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.100
121381592002Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration.91
236983102013Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry.83
249040852014Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes.83
209809782011Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase.82
235994082013Performance of kidney injury molecule-1 and liver fatty acid-binding protein and combined biomarkers of AKI after cardiac surgery.75
195728012009Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass.67

Citation

Dessen P

HAVCR1 (hepatitis A virus cellular receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40789/havcr1