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HCAR2 (hydroxycarboxylic acid receptor 2)

Identity

Alias_namesGPR109A
G protein-coupled receptor 109A
Alias_symbol (synonym)HCA2
HM74A
PUMAG
Puma-g
NIACR1
Other aliasHM74a
HM74b
HGNC (Hugo) HCAR2
LocusID (NCBI) 338442
Atlas_Id 52400
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 122701293 and ends at 122703357 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HCAR2   24827
Cards
Entrez_Gene (NCBI)HCAR2  338442  hydroxycarboxylic acid receptor 2
AliasesGPR109A; HCA2; HM74a; HM74b; 
NIACR1; PUMAG; Puma-g
GeneCards (Weizmann)HCAR2
Ensembl hg19 (Hinxton)ENSG00000182782 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182782 [Gene_View]  chr12:122701293-122703357 [Contig_View]  HCAR2 [Vega]
ICGC DataPortalENSG00000182782
TCGA cBioPortalHCAR2
AceView (NCBI)HCAR2
Genatlas (Paris)HCAR2
WikiGenes338442
SOURCE (Princeton)HCAR2
Genetics Home Reference (NIH)HCAR2
Genomic and cartography
GoldenPath hg38 (UCSC)HCAR2  -     chr12:122701293-122703357 -  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HCAR2  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblHCAR2 - 12q24.31 [CytoView hg19]  HCAR2 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIHCAR2 [Mapview hg19]  HCAR2 [Mapview hg38]
OMIM609163   
Gene and transcription
Genbank (Entrez)AK290915 AL572062 AL698846 AY148884 BC027965
RefSeq transcript (Entrez)NM_177551
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HCAR2
Cluster EST : UnigeneHs.524812 [ NCBI ]
CGAP (NCI)Hs.524812
Alternative Splicing GalleryENSG00000182782
Gene ExpressionHCAR2 [ NCBI-GEO ]   HCAR2 [ EBI - ARRAY_EXPRESS ]   HCAR2 [ SEEK ]   HCAR2 [ MEM ]
Gene Expression Viewer (FireBrowse)HCAR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)338442
GTEX Portal (Tissue expression)HCAR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDS4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDS4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDS4
Splice isoforms : SwissVarQ8TDS4
PhosPhoSitePlusQ8TDS4
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    HCAR2/3_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)HCAR2
DMDM Disease mutations338442
Blocks (Seattle)HCAR2
SuperfamilyQ8TDS4
Human Protein AtlasENSG00000182782
Peptide AtlasQ8TDS4
HPRD16453
IPIIPI00157746   IPI01014769   IPI00386383   
Protein Interaction databases
DIP (DOE-UCLA)Q8TDS4
IntAct (EBI)Q8TDS4
FunCoupENSG00000182782
BioGRIDHCAR2
STRING (EMBL)HCAR2
ZODIACHCAR2
Ontologies - Pathways
QuickGOQ8TDS4
Ontology : AmiGOneutrophil apoptotic process  plasma membrane  plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  cell junction  positive regulation of neutrophil apoptotic process  negative regulation of lipid catabolic process  positive regulation of adiponectin secretion  nicotinic acid receptor activity  
Ontology : EGO-EBIneutrophil apoptotic process  plasma membrane  plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  cell junction  positive regulation of neutrophil apoptotic process  negative regulation of lipid catabolic process  positive regulation of adiponectin secretion  nicotinic acid receptor activity  
NDEx NetworkHCAR2
Atlas of Cancer Signalling NetworkHCAR2
Wikipedia pathwaysHCAR2
Orthology - Evolution
OrthoDB338442
GeneTree (enSembl)ENSG00000182782
Phylogenetic Trees/Animal Genes : TreeFamHCAR2
HOVERGENQ8TDS4
HOGENOMQ8TDS4
Homologs : HomoloGeneHCAR2
Homology/Alignments : Family Browser (UCSC)HCAR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHCAR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HCAR2
dbVarHCAR2
ClinVarHCAR2
1000_GenomesHCAR2 
Exome Variant ServerHCAR2
ExAC (Exome Aggregation Consortium)HCAR2 (select the gene name)
Genetic variants : HAPMAP338442
Genomic Variants (DGV)HCAR2 [DGVbeta]
DECIPHERHCAR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHCAR2 
Mutations
ICGC Data PortalHCAR2 
TCGA Data PortalHCAR2 
Broad Tumor PortalHCAR2
OASIS PortalHCAR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHCAR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHCAR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HCAR2
DgiDB (Drug Gene Interaction Database)HCAR2
DoCM (Curated mutations)HCAR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HCAR2 (select a term)
intoGenHCAR2
Cancer3DHCAR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609163   
Orphanet
MedgenHCAR2
Genetic Testing Registry HCAR2
NextProtQ8TDS4 [Medical]
TSGene338442
GENETestsHCAR2
Target ValidationHCAR2
Huge Navigator HCAR2 [HugePedia]
snp3D : Map Gene to Disease338442
BioCentury BCIQHCAR2
ClinGenHCAR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD338442
Chemical/Pharm GKB GenePA165961843
Clinical trialHCAR2
Miscellaneous
canSAR (ICR)HCAR2 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHCAR2
EVEXHCAR2
GoPubMedHCAR2
iHOPHCAR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:02:46 CEST 2017

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