HCFC1R1 (host cell factor C1 regulator 1)

2016-01-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
HPIP
FUSION GENES

Other Information

Locus ID:

NCBI: 54985
MIM: 618818
HGNC: 21198
Ensembl: ENSG00000103145

Variants:

dbSNP: 54985
ClinVar: 54985
TCGA: ENSG00000103145
COSMIC: HCFC1R1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103145ENST00000248089Q9NWW0
ENSG00000103145ENST00000354679J3KNY1
ENSG00000103145ENST00000572355I3L1N5
ENSG00000103145ENST00000573842I3L174
ENSG00000103145ENST00000574151Q9NWW0
ENSG00000103145ENST00000574980Q9NWW0

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
258007932015HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.21
264636292015HPIP promotes thyroid cancer cell growth, migration and EMT through activating PI3K/AKT signaling pathway.16
122351382002Interaction of HCF-1 with a cellular nuclear export factor.11
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
278182892017HPIP expression predicts chemoresistance and poor clinical outcomes in patients with epithelial ovarian cancer.5

Citation

Dessen P

HCFC1R1 (host cell factor C1 regulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55592/hcfc1r1