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HDAC10 (histone deacetylase 10)

Identity

Alias (NCBI)HD10
HGNC (Hugo) HDAC10
HGNC Alias symbDKFZP761B039
LocusID (NCBI) 83933
Atlas_Id 43706
Location 22q13.33  [Link to chromosome band 22q13]
Location_base_pair Starts at 50245184 and ends at 50251265 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HDAC10 (22q13.33) / SNRNP70 (19q13.33)PSMD2 (3q27.1) / HDAC10 (22q13.33)SNRNP70 (19q13.33) / HDAC10 (22q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HDAC10   18128
Cards
Entrez_Gene (NCBI)HDAC10    histone deacetylase 10
AliasesHD10
GeneCards (Weizmann)HDAC10
Ensembl hg19 (Hinxton)ENSG00000100429 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100429 [Gene_View]  ENSG00000100429 [Sequence]  chr22:50245184-50251265 [Contig_View]  HDAC10 [Vega]
ICGC DataPortalENSG00000100429
TCGA cBioPortalHDAC10
AceView (NCBI)HDAC10
Genatlas (Paris)HDAC10
SOURCE (Princeton)HDAC10
Genetics Home Reference (NIH)HDAC10
Genomic and cartography
GoldenPath hg38 (UCSC)HDAC10  -     chr22:50245184-50251265 -  22q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HDAC10  -     22q13.33   [Description]    (hg19-Feb_2009)
GoldenPathHDAC10 - 22q13.33 [CytoView hg19]  HDAC10 - 22q13.33 [CytoView hg38]
ImmunoBaseENSG00000100429
Genome Data Viewer NCBIHDAC10 [Mapview hg19]  
OMIM608544   
Gene and transcription
Genbank (Entrez)AF393962 AF407272 AF407273 AF426160 AL512711
RefSeq transcript (Entrez)NM_001159286 NM_032019
Consensus coding sequences : CCDS (NCBI)HDAC10
Gene ExpressionHDAC10 [ NCBI-GEO ]   HDAC10 [ EBI - ARRAY_EXPRESS ]   HDAC10 [ SEEK ]   HDAC10 [ MEM ]
Gene Expression Viewer (FireBrowse)HDAC10 [ Firebrowse - Broad ]
GenevisibleExpression of HDAC10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83933
GTEX Portal (Tissue expression)HDAC10
Human Protein AtlasENSG00000100429-HDAC10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969S8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969S8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969S8
PhosPhoSitePlusQ969S8
Domains : Interpro (EBI)His_deacetylse    His_deacetylse_dom    His_deacetylse_dom_sf    Ureohydrolase_dom_sf   
Domain families : Pfam (Sanger)Hist_deacetyl (PF00850)   
Domain families : Pfam (NCBI)pfam00850   
Conserved Domain (NCBI)HDAC10
SuperfamilyQ969S8
AlphaFold pdb e-kbQ969S8   
Human Protein Atlas [tissue]ENSG00000100429-HDAC10 [tissue]
HPRD09407
Protein Interaction databases
DIP (DOE-UCLA)Q969S8
IntAct (EBI)Q969S8
BioGRIDHDAC10
STRING (EMBL)HDAC10
ZODIACHDAC10
Ontologies - Pathways
QuickGOQ969S8
Ontology : AmiGOhistone deacetylase complex  negative regulation of transcription by RNA polymerase II  histone deacetylase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  DNA repair  chromatin organization  regulation of transcription, DNA-templated  transcription initiation from RNA polymerase II promoter  protein deacetylation  protein deacetylation  zinc ion binding  oligodendrocyte development  macroautophagy  histone deacetylation  deacetylase activity  enzyme binding  positive regulation of mismatch repair  protein deacetylase activity  protein deacetylase activity  peptidyl-lysine deacetylation  homologous recombination  histone deacetylase binding  negative regulation of transcription, DNA-templated  acetylputrescine deacetylase activity  acetylspermidine deacetylase activity  polyamine deacetylation  spermidine deacetylation  
Ontology : EGO-EBIhistone deacetylase complex  negative regulation of transcription by RNA polymerase II  histone deacetylase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  DNA repair  chromatin organization  regulation of transcription, DNA-templated  transcription initiation from RNA polymerase II promoter  protein deacetylation  protein deacetylation  zinc ion binding  oligodendrocyte development  macroautophagy  histone deacetylation  deacetylase activity  enzyme binding  positive regulation of mismatch repair  protein deacetylase activity  protein deacetylase activity  peptidyl-lysine deacetylation  homologous recombination  histone deacetylase binding  negative regulation of transcription, DNA-templated  acetylputrescine deacetylase activity  acetylspermidine deacetylase activity  polyamine deacetylation  spermidine deacetylation  
Pathways : KEGGAlcoholism    Viral carcinogenesis   
NDEx NetworkHDAC10
Atlas of Cancer Signalling NetworkHDAC10
Wikipedia pathwaysHDAC10
Orthology - Evolution
OrthoDB83933
GeneTree (enSembl)ENSG00000100429
Phylogenetic Trees/Animal Genes : TreeFamHDAC10
Homologs : HomoloGeneHDAC10
Homology/Alignments : Family Browser (UCSC)HDAC10
Gene fusions - Rearrangements
Fusion : QuiverHDAC10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHDAC10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HDAC10
dbVarHDAC10
ClinVarHDAC10
MonarchHDAC10
1000_GenomesHDAC10 
Exome Variant ServerHDAC10
GNOMAD BrowserENSG00000100429
Varsome BrowserHDAC10
ACMGHDAC10 variants
VarityQ969S8
Genomic Variants (DGV)HDAC10 [DGVbeta]
DECIPHERHDAC10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHDAC10 
Mutations
ICGC Data PortalHDAC10 
TCGA Data PortalHDAC10 
Broad Tumor PortalHDAC10
OASIS PortalHDAC10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHDAC10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHDAC10
Mutations and Diseases : HGMDHDAC10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHDAC10
DgiDB (Drug Gene Interaction Database)HDAC10
DoCM (Curated mutations)HDAC10
CIViC (Clinical Interpretations of Variants in Cancer)HDAC10
Cancer3DHDAC10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608544   
Orphanet
DisGeNETHDAC10
MedgenHDAC10
Genetic Testing Registry HDAC10
NextProtQ969S8 [Medical]
GENETestsHDAC10
Target ValidationHDAC10
Huge Navigator HDAC10 [HugePedia]
ClinGenHDAC10
Clinical trials, drugs, therapy
MyCancerGenomeHDAC10
Protein Interactions : CTDHDAC10
Pharm GKB GenePA38297
PharosQ969S8
Clinical trialHDAC10
Miscellaneous
canSAR (ICR)HDAC10
HarmonizomeHDAC10
DataMed IndexHDAC10
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHDAC10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:12:09 CEST 2021

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