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HDAC10 (histone deacetylase 10)

Identity

Alias_symbol (synonym)DKFZP761B039
Other aliasHD10
HGNC (Hugo) HDAC10
LocusID (NCBI) 83933
Atlas_Id 43706
Location 22q13.33  [Link to chromosome band 22q13]
Location_base_pair Starts at 50245184 and ends at 50251405 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HDAC10 (22q13.33) / SNRNP70 (19q13.33)PSMD2 (3q27.1) / HDAC10 (22q13.33)SNRNP70 (19q13.33) / HDAC10 (22q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HDAC10   18128
Cards
Entrez_Gene (NCBI)HDAC10  83933  histone deacetylase 10
AliasesHD10
GeneCards (Weizmann)HDAC10
Ensembl hg19 (Hinxton)ENSG00000100429 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100429 [Gene_View]  chr22:50245184-50251405 [Contig_View]  HDAC10 [Vega]
ICGC DataPortalENSG00000100429
TCGA cBioPortalHDAC10
AceView (NCBI)HDAC10
Genatlas (Paris)HDAC10
WikiGenes83933
SOURCE (Princeton)HDAC10
Genetics Home Reference (NIH)HDAC10
Genomic and cartography
GoldenPath hg38 (UCSC)HDAC10  -     chr22:50245184-50251405 -  22q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HDAC10  -     22q13.33   [Description]    (hg19-Feb_2009)
EnsemblHDAC10 - 22q13.33 [CytoView hg19]  HDAC10 - 22q13.33 [CytoView hg38]
Mapping of homologs : NCBIHDAC10 [Mapview hg19]  HDAC10 [Mapview hg38]
OMIM608544   
Gene and transcription
Genbank (Entrez)AF393962 AF407272 AF407273 AF426160 AL512711
RefSeq transcript (Entrez)NM_001159286 NM_032019
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HDAC10
Cluster EST : UnigeneHs.26593 [ NCBI ]
CGAP (NCI)Hs.26593
Alternative Splicing GalleryENSG00000100429
Gene ExpressionHDAC10 [ NCBI-GEO ]   HDAC10 [ EBI - ARRAY_EXPRESS ]   HDAC10 [ SEEK ]   HDAC10 [ MEM ]
Gene Expression Viewer (FireBrowse)HDAC10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83933
GTEX Portal (Tissue expression)HDAC10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969S8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969S8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969S8
Splice isoforms : SwissVarQ969S8
PhosPhoSitePlusQ969S8
Domains : Interpro (EBI)His_deacetylse    His_deacetylse_dom   
Domain families : Pfam (Sanger)Hist_deacetyl (PF00850)   
Domain families : Pfam (NCBI)pfam00850   
Conserved Domain (NCBI)HDAC10
DMDM Disease mutations83933
Blocks (Seattle)HDAC10
SuperfamilyQ969S8
Human Protein AtlasENSG00000100429
Peptide AtlasQ969S8
HPRD09407
IPIIPI00012439   IPI00216339   IPI00216341   IPI00879495   IPI00973206   IPI00852736   IPI00446419   
Protein Interaction databases
DIP (DOE-UCLA)Q969S8
IntAct (EBI)Q969S8
FunCoupENSG00000100429
BioGRIDHDAC10
STRING (EMBL)HDAC10
ZODIACHDAC10
Ontologies - Pathways
QuickGOQ969S8
Ontology : AmiGOhistone deacetylase complex  negative regulation of transcription from RNA polymerase II promoter  histone deacetylase activity  histone deacetylase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  chromatin organization  transcription, DNA-templated  regulation of transcription, DNA-templated  protein deacetylation  oligodendrocyte development  histone deacetylation  enzyme binding  NAD-dependent histone deacetylase activity (H3-K14 specific)  protein deacetylase activity  histone deacetylase binding  negative regulation of transcription, DNA-templated  histone H3 deacetylation  
Ontology : EGO-EBIhistone deacetylase complex  negative regulation of transcription from RNA polymerase II promoter  histone deacetylase activity  histone deacetylase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  chromatin organization  transcription, DNA-templated  regulation of transcription, DNA-templated  protein deacetylation  oligodendrocyte development  histone deacetylation  enzyme binding  NAD-dependent histone deacetylase activity (H3-K14 specific)  protein deacetylase activity  histone deacetylase binding  negative regulation of transcription, DNA-templated  histone H3 deacetylation  
Pathways : KEGGAlcoholism    Viral carcinogenesis   
NDEx NetworkHDAC10
Atlas of Cancer Signalling NetworkHDAC10
Wikipedia pathwaysHDAC10
Orthology - Evolution
OrthoDB83933
GeneTree (enSembl)ENSG00000100429
Phylogenetic Trees/Animal Genes : TreeFamHDAC10
HOVERGENQ969S8
HOGENOMQ969S8
Homologs : HomoloGeneHDAC10
Homology/Alignments : Family Browser (UCSC)HDAC10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHDAC10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HDAC10
dbVarHDAC10
ClinVarHDAC10
1000_GenomesHDAC10 
Exome Variant ServerHDAC10
ExAC (Exome Aggregation Consortium)HDAC10 (select the gene name)
Genetic variants : HAPMAP83933
Genomic Variants (DGV)HDAC10 [DGVbeta]
DECIPHERHDAC10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHDAC10 
Mutations
ICGC Data PortalHDAC10 
TCGA Data PortalHDAC10 
Broad Tumor PortalHDAC10
OASIS PortalHDAC10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHDAC10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHDAC10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HDAC10
DgiDB (Drug Gene Interaction Database)HDAC10
DoCM (Curated mutations)HDAC10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HDAC10 (select a term)
intoGenHDAC10
Cancer3DHDAC10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608544   
Orphanet
MedgenHDAC10
Genetic Testing Registry HDAC10
NextProtQ969S8 [Medical]
TSGene83933
GENETestsHDAC10
Target ValidationHDAC10
Huge Navigator HDAC10 [HugePedia]
snp3D : Map Gene to Disease83933
BioCentury BCIQHDAC10
ClinGenHDAC10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83933
Chemical/Pharm GKB GenePA38297
Clinical trialHDAC10
Miscellaneous
canSAR (ICR)HDAC10 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHDAC10
EVEXHDAC10
GoPubMedHDAC10
iHOPHDAC10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:11:11 CEST 2017

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