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HDAC7 (histone deacetylase 7)

Identity

Other namesHD7A
HDAC7A
HGNC (Hugo) HDAC7
LocusID (NCBI) 51564
Location 12q13.11
Location_base_pair Starts at 48176507 and ends at 48213763 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)HDAC7   14067
Entrez_Gene (NCBI)HDAC7  51564  histone deacetylase 7
Cards
GeneCards (Weizmann)HDAC7
Ensembl (Hinxton)ENSG00000061273 [Gene_View]  chr12:48176507-48213763 [Contig_View]  HDAC7 [Vega]
AceView (NCBI)HDAC7
Genatlas (Paris)HDAC7
SOURCE (Stanford)NM_001098416 NM_015401 NM_016596
Genomic and cartography
GoldenPath (UCSC)HDAC7  -  12q13.11   chr12:48176507-48213763 -  12q13.11   [Description]    (hg19-Feb_2009)
EnsemblHDAC7 - 12q13.11 [CytoView]
Mapping of homologs : NCBIHDAC7 [Mapview]
OMIM606542   
Gene and transcription
Genbank (Entrez)AF239243 AK001032 AK001190 AK024387 AK024469
RefSeq transcript (SRS)NM_001098416 NM_015401 NM_016596
RefSeq transcript (Entrez)NM_001098416 NM_015401 NM_016596
RefSeq genomic (SRS)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004078075
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004078075
Consensus coding sequences : CCDS (NCBI)HDAC7
Cluster EST : UnigeneHs.200063 [ SRS ] Hs.200063 [ NCBI ]
CGAP (NCI)Hs.200063
Alternative Splicing : Fast-db (Paris)GSHG0007411
Alternative Splicing GalleryENSG00000061273
Gene ExpressionHDAC7 [ NCBI-GEO ]   HDAC7 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUI4 (SRS) Q8WUI4 (Uniprot)
NextProtQ8WUI4
With graphics : InterProQ8WUI4
Splice isoforms : SwissVarQ8WUI4(Swissvar)
Domains : Interpro (SRS)His_deacetylse    His_deacetylse_dom    Histone_deAcase_II_euk   
Domains : Interpro (EBI)His_deacetylse    His_deacetylse_dom    Histone_deAcase_II_euk   
Related proteins : CluSTrQ8WUI4
Domain families : Pfam (SRS)Hist_deacetyl (PF00850)   
Domain families : Pfam (Sanger)Hist_deacetyl (PF00850)   
Domain families : Pfam (NCBI)pfam00850   
DMDM51564
Blocks (Seattle)Q8WUI4
PDB (SRS)3C0Y    3C0Z    3C10   
PDB (PDBSum)3C0Y    3C0Z    3C10   
PDB (IMB)3C0Y    3C0Z    3C10   
PDB (RSDB)3C0Y    3C0Z    3C10   
Human Protein AtlasENSG00000061273
HPRD09133
IPIIPI00743474   IPI00944518   IPI00306189   IPI00917034   IPI00386808   IPI00916348   IPI00916810   IPI00916470   IPI00909569   IPI00944634   IPI00386149   IPI01021992   IPI01020891   IPI01025119   IPI01020789   IPI00916633   IPI00916795   IPI00418482   IPI00917355   IPI00916377   IPI00916494   IPI01017881   IPI00916978   IPI00917167   IPI00917256   
Protein Interaction databases
DIP (DOE-UCLA)Q8WUI4
IntAct (EBI)Q8WUI4
FunCoupENSG00000061273
REACTOMEHDAC7
Protein Interaction Database51564
BioGRIDHDAC7
InParanoidQ8WUI4
Interologous Interaction database Q8WUI4
IntegromeDBHDAC7
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)HDAC7
SNP (GeneSNP Utah)HDAC7
SNP : HGBaseHDAC7
Genetic variants : HAPMAPHDAC7
Somatic Mutations in Cancer : COSMICHDAC7 
CONAN: Copy Number AnalysisHDAC7 
Mutations and Diseases : HGMDHDAC7
OMIM606542   
GENETests606542   
Disease Genetic AssociationHDAC7
Huge Navigator HDAC7 [HugePedia]  HDAC7 [HugeCancerGEM]
Genomic VariantsHDAC7  HDAC7 [DGVbeta]
snp3D : Map Gene to Disease51564
General knowledge
Homologs : HomoloGeneHDAC7
Homology/Alignments : Family Browser (UCSC)HDAC7
Phylogenetic Trees/Animal Genes : TreeFamHDAC7
Catalytic activity : Enzyme3.5.1.98 [ Enzyme-Expasy ]   3.5.1.98 [ Enzyme-SRS ]   3.5.1.98 [ IntEnz-EBI ]   3.5.1.98 [ BRENDA ]   3.5.1.98 [ KEGG ]   
Chemical/Protein Interactions : CTD51564
Chemical/Pharm GKB GenePA162390579
Clinical trialHDAC7
Cancer Resource (Charite)ENSG00000061273
Ontology : AmiGOhistone deacetylase complex  negative regulation of transcription from RNA polymerase II promoter  vasculogenesis  chromatin binding  transcription corepressor activity  protein kinase C binding  nucleus  cytoplasm  transcription, DNA-dependent  cell-cell junction assembly  Notch signaling pathway  protein kinase binding  NAD-dependent histone deacetylase activity (H3-K14 specific)  negative regulation of interleukin-2 production  activating transcription factor binding  negative regulation of osteoblast differentiation  metal ion binding  NAD-dependent histone deacetylase activity (H3-K9 specific)  NAD-dependent histone deacetylase activity (H4-K16 specific)  repressing transcription factor binding  14-3-3 protein binding  positive regulation of cell migration involved in sprouting angiogenesis  NAD-dependent histone deacetylase activity (H3-K18 specific)  
Ontology : EGO-EBIhistone deacetylase complex  negative regulation of transcription from RNA polymerase II promoter  vasculogenesis  chromatin binding  transcription corepressor activity  protein kinase C binding  nucleus  cytoplasm  transcription, DNA-dependent  cell-cell junction assembly  Notch signaling pathway  protein kinase binding  NAD-dependent histone deacetylase activity (H3-K14 specific)  negative regulation of interleukin-2 production  activating transcription factor binding  negative regulation of osteoblast differentiation  metal ion binding  NAD-dependent histone deacetylase activity (H3-K9 specific)  NAD-dependent histone deacetylase activity (H4-K16 specific)  repressing transcription factor binding  14-3-3 protein binding  positive regulation of cell migration involved in sprouting angiogenesis  NAD-dependent histone deacetylase activity (H3-K18 specific)  
Other databases
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
PubGeneHDAC7
iHOPHDAC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:33:47 CEST 2013
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