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HDAC9 (histone deacetylase 9)

Identity

Other namesHD7
HD7b
HD9
HDAC
HDAC7
HDAC7B
HDAC9B
HDAC9FL
HDRP
MITR
HGNC (Hugo) HDAC9
LocusID (NCBI) 9734
Atlas_Id 40808
Location 7p21.1  [Link to chromosome band 7p21]
Location_base_pair Starts at 18126572 and ends at 18708466 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARHGEF12 (11q23.3) / HDAC9 (7p21.1)HDAC9 (7p21.1) / AC010859.1 ()HDAC9 (7p21.1) / DGKB (7p21.2)
HDAC9 (7p21.1) / MCMBP (10q26.11)HDAC9 (7p21.1) / PPL (16p13.3)HDAC9 (7p21.1) / SNX10 (7p15.2)
TSPAN8 (12q21.1) / HDAC9 (7p21.1)HDAC9 7p21.1 AC010859.1HDAC9 7p21.1 / PPL 16p13.3
HDAC9 7p21.1 / SNX10 7p15.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 0 ]
  Neuro-Endocrine/Endocrine System: Carcinoid tumors

External links

Nomenclature
HGNC (Hugo)HDAC9   14065
Cards
Entrez_Gene (NCBI)HDAC9  9734  histone deacetylase 9
AliasesHD7; HD7b; HD9; HDAC; 
HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; MITR
GeneCards (Weizmann)HDAC9
Ensembl hg19 (Hinxton)ENSG00000048052 [Gene_View]  chr7:18126572-18708466 [Contig_View]  HDAC9 [Vega]
Ensembl hg38 (Hinxton)ENSG00000048052 [Gene_View]  chr7:18126572-18708466 [Contig_View]  HDAC9 [Vega]
ICGC DataPortalENSG00000048052
TCGA cBioPortalHDAC9
AceView (NCBI)HDAC9
Genatlas (Paris)HDAC9
WikiGenes9734
SOURCE (Princeton)HDAC9
Genomic and cartography
GoldenPath hg19 (UCSC)HDAC9  -     chr7:18126572-18708466 +  7p21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HDAC9  -     7p21.1   [Description]    (hg38-Dec_2013)
EnsemblHDAC9 - 7p21.1 [CytoView hg19]  HDAC9 - 7p21.1 [CytoView hg38]
Mapping of homologs : NCBIHDAC9 [Mapview hg19]  HDAC9 [Mapview hg38]
OMIM606543   
Gene and transcription
Genbank (Entrez)AA405905 AB018287 AF124924 AJ459808 AK095820
RefSeq transcript (Entrez)NM_001204144 NM_001204145 NM_001204146 NM_001204147 NM_001204148 NM_001321868 NM_001321869 NM_001321870 NM_001321871 NM_001321872 NM_001321873 NM_001321874 NM_001321875 NM_001321876 NM_001321877 NM_001321878 NM_001321879 NM_001321884 NM_001321885 NM_001321886 NM_001321887 NM_001321888 NM_001321889 NM_001321890 NM_001321891 NM_001321893 NM_001321894 NM_001321895 NM_001321896 NM_001321897 NM_001321898 NM_001321899 NM_001321900 NM_001321901 NM_001321902 NM_014707 NM_058176 NM_058177 NM_178423 NM_178425
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_023250 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)HDAC9
Cluster EST : UnigeneHs.444785 [ NCBI ]
CGAP (NCI)Hs.444785
Alternative Splicing GalleryENSG00000048052
Gene ExpressionHDAC9 [ NCBI-GEO ]   HDAC9 [ EBI - ARRAY_EXPRESS ]   HDAC9 [ SEEK ]   HDAC9 [ MEM ]
Gene Expression Viewer (FireBrowse)HDAC9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9734
GTEX Portal (Tissue expression)HDAC9
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKV0 (Uniprot)
NextProtQ9UKV0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKV0
Splice isoforms : SwissVarQ9UKV0 (Swissvar)
Catalytic activity : Enzyme3.5.1.98 [ Enzyme-Expasy ]   3.5.1.983.5.1.98 [ IntEnz-EBI ]   3.5.1.98 [ BRENDA ]   3.5.1.98 [ KEGG ]   
PhosPhoSitePlusQ9UKV0
Domains : Interpro (EBI)His_deacetylse    His_deacetylse_dom    Hist_deacetylase_Gln_rich_N    Histone_deAcase_II_euk   
Domain families : Pfam (Sanger)HDAC4_Gln (PF12203)    Hist_deacetyl (PF00850)   
Domain families : Pfam (NCBI)pfam12203    pfam00850   
DMDM Disease mutations9734
Blocks (Seattle)HDAC9
SuperfamilyQ9UKV0
Human Protein AtlasENSG00000048052
Peptide AtlasQ9UKV0
HPRD05944
IPIIPI00232519   IPI00215728   IPI00215729   IPI00215730   IPI00829837   IPI00829883   IPI00328781   IPI00974086   IPI00974194   IPI00894548   IPI00894305   IPI00894119   IPI00893998   IPI00983752   IPI00893751   IPI00980189   IPI00893441   IPI01011786   IPI00936847   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKV0
IntAct (EBI)Q9UKV0
FunCoupENSG00000048052
BioGRIDHDAC9
STRING (EMBL)HDAC9
ZODIACHDAC9
Ontologies - Pathways
QuickGOQ9UKV0
Ontology : AmiGOhistone deacetylase complex  negative regulation of transcription from RNA polymerase II promoter  response to amphetamine  transcription corepressor activity  histone deacetylase activity  histone deacetylase activity  protein kinase C binding  protein binding  nucleus  nucleoplasm  transcription factor complex  cytoplasm  cytoplasm  transcription, DNA-templated  inflammatory response  heart development  transcription factor binding  transcription factor binding  histone deacetylation  neuron differentiation  B cell differentiation  NAD-dependent histone deacetylase activity (H3-K14 specific)  cellular response to insulin stimulus  protein deacetylase activity  peptidyl-lysine deacetylation  histone methyltransferase complex  B cell activation  histone deacetylase binding  histone deacetylase binding  negative regulation of transcription, DNA-templated  metal ion binding  regulation of skeletal muscle fiber development  regulation of striated muscle cell differentiation  repressing transcription factor binding  repressing transcription factor binding  repressing transcription factor binding  histone H3 deacetylation  histone H4 deacetylation  positive regulation of cell migration involved in sprouting angiogenesis  
Ontology : EGO-EBIhistone deacetylase complex  negative regulation of transcription from RNA polymerase II promoter  response to amphetamine  transcription corepressor activity  histone deacetylase activity  histone deacetylase activity  protein kinase C binding  protein binding  nucleus  nucleoplasm  transcription factor complex  cytoplasm  cytoplasm  transcription, DNA-templated  inflammatory response  heart development  transcription factor binding  transcription factor binding  histone deacetylation  neuron differentiation  B cell differentiation  NAD-dependent histone deacetylase activity (H3-K14 specific)  cellular response to insulin stimulus  protein deacetylase activity  peptidyl-lysine deacetylation  histone methyltransferase complex  B cell activation  histone deacetylase binding  histone deacetylase binding  negative regulation of transcription, DNA-templated  metal ion binding  regulation of skeletal muscle fiber development  regulation of striated muscle cell differentiation  repressing transcription factor binding  repressing transcription factor binding  repressing transcription factor binding  histone H3 deacetylation  histone H4 deacetylation  positive regulation of cell migration involved in sprouting angiogenesis  
Pathways : BIOCARTASumoylation by RanBP2 Regulates Transcriptional Repression [Genes]    Signal Dependent Regulation of Myogenesis by Corepressor MITR [Genes]   
Pathways : KEGGAlcoholism    Viral carcinogenesis   
NDEx NetworkHDAC9
Atlas of Cancer Signalling NetworkHDAC9
Wikipedia pathwaysHDAC9
Orthology - Evolution
OrthoDB9734
GeneTree (enSembl)ENSG00000048052
Phylogenetic Trees/Animal Genes : TreeFamHDAC9
Homologs : HomoloGeneHDAC9
Homology/Alignments : Family Browser (UCSC)HDAC9
Gene fusions - Rearrangements
Fusion: TCGAHDAC9 7p21.1 AC010859.1 LGG
Fusion: TCGAHDAC9 7p21.1 PPL 16p13.3 BRCA
Fusion: TCGAHDAC9 7p21.1 SNX10 7p15.2 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerHDAC9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HDAC9
dbVarHDAC9
ClinVarHDAC9
1000_GenomesHDAC9 
Exome Variant ServerHDAC9
ExAC (Exome Aggregation Consortium)HDAC9 (select the gene name)
Genetic variants : HAPMAP9734
Genomic Variants (DGV)HDAC9 [DGVbeta]
Mutations
ICGC Data PortalHDAC9 
TCGA Data PortalHDAC9 
Broad Tumor PortalHDAC9
OASIS PortalHDAC9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHDAC9 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HDAC9
DgiDB (Drug Gene Interaction Database)HDAC9
DoCM (Curated mutations)HDAC9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HDAC9 (select a term)
intoGenHDAC9
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)7:18126572-18708466  ENSG00000048052
CONAN: Copy Number AnalysisHDAC9 
Mutations and Diseases : HGMDHDAC9
OMIM606543   
MedgenHDAC9
Genetic Testing Registry HDAC9
NextProtQ9UKV0 [Medical]
TSGene9734
GENETestsHDAC9
Huge Navigator HDAC9 [HugePedia]
snp3D : Map Gene to Disease9734
BioCentury BCIQHDAC9
ClinGenHDAC9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9734
Chemical/Pharm GKB GenePA38377
Clinical trialHDAC9
Miscellaneous
canSAR (ICR)HDAC9 (select the gene name)
Probes
Litterature
PubMed104 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHDAC9
EVEXHDAC9
GoPubMedHDAC9
iHOPHDAC9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 19 18:52:29 CEST 2016

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