Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HDC (histidine decarboxylase)

Identity

Alias (NCBI)-
HGNC (Hugo) HDC
LocusID (NCBI) 3067
Atlas_Id 46224
Location 15q21.2  [Link to chromosome band 15q21]
Location_base_pair Starts at 50241949 and ends at 50265726 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)HDC   4855
Cards
Entrez_Gene (NCBI)HDC  3067  histidine decarboxylase
Aliases
GeneCards (Weizmann)HDC
Ensembl hg19 (Hinxton)ENSG00000140287 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140287 [Gene_View]  ENSG00000140287 [Sequence]  chr15:50241949-50265726 [Contig_View]  HDC [Vega]
ICGC DataPortalENSG00000140287
TCGA cBioPortalHDC
AceView (NCBI)HDC
Genatlas (Paris)HDC
WikiGenes3067
SOURCE (Princeton)HDC
Genetics Home Reference (NIH)HDC
Genomic and cartography
GoldenPath hg38 (UCSC)HDC  -     chr15:50241949-50265726 -  15q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HDC  -     15q21.2   [Description]    (hg19-Feb_2009)
GoldenPathHDC - 15q21.2 [CytoView hg19]  HDC - 15q21.2 [CytoView hg38]
ImmunoBaseENSG00000140287
genome Data Viewer NCBIHDC [Mapview hg19]  
OMIM137580   142704   
Gene and transcription
Genbank (Entrez)AK027221 AK308833 AK310479 AK311072 AL041199
RefSeq transcript (Entrez)NM_001306146 NM_002112
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HDC
Alternative Splicing GalleryENSG00000140287
Gene ExpressionHDC [ NCBI-GEO ]   HDC [ EBI - ARRAY_EXPRESS ]   HDC [ SEEK ]   HDC [ MEM ]
Gene Expression Viewer (FireBrowse)HDC [ Firebrowse - Broad ]
GenevisibleExpression of HDC in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3067
GTEX Portal (Tissue expression)HDC
Human Protein AtlasENSG00000140287-HDC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19113   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19113  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19113
Splice isoforms : SwissVarP19113
PhosPhoSitePlusP19113
Domaine pattern : Prosite (Expaxy)DDC_GAD_HDC_YDC (PS00392)   
Domains : Interpro (EBI)Aromatic_deC    PyrdxlP-dep_de-COase    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_dom1    PyrdxlP-dep_Trfase_major    Pyridoxal-P_BS   
Domain families : Pfam (Sanger)Pyridoxal_deC (PF00282)   
Domain families : Pfam (NCBI)pfam00282   
Conserved Domain (NCBI)HDC
DMDM Disease mutations3067
Blocks (Seattle)HDC
PDB (RSDB)4E1O   
PDB Europe4E1O   
PDB (PDBSum)4E1O   
PDB (IMB)4E1O   
Structural Biology KnowledgeBase4E1O   
SCOP (Structural Classification of Proteins)4E1O   
CATH (Classification of proteins structures)4E1O   
SuperfamilyP19113
Human Protein Atlas [tissue]ENSG00000140287-HDC [tissue]
Peptide AtlasP19113
HPRD00817
IPIIPI00290368   IPI01009693   
Protein Interaction databases
DIP (DOE-UCLA)P19113
IntAct (EBI)P19113
FunCoupENSG00000140287
BioGRIDHDC
STRING (EMBL)HDC
ZODIACHDC
Ontologies - Pathways
QuickGOP19113
Ontology : AmiGOhistamine biosynthetic process  histamine biosynthetic process  histamine biosynthetic process  histamine biosynthetic process  histidine decarboxylase activity  histidine decarboxylase activity  protein binding  cytoplasm  cytosol  histidine metabolic process  histidine catabolic process  histidine catabolic process  carboxy-lyase activity  pyridoxal phosphate binding  catecholamine biosynthetic process  
Ontology : EGO-EBIhistamine biosynthetic process  histamine biosynthetic process  histamine biosynthetic process  histamine biosynthetic process  histidine decarboxylase activity  histidine decarboxylase activity  protein binding  cytoplasm  cytosol  histidine metabolic process  histidine catabolic process  histidine catabolic process  carboxy-lyase activity  pyridoxal phosphate binding  catecholamine biosynthetic process  
Pathways : KEGGHistidine metabolism   
NDEx NetworkHDC
Atlas of Cancer Signalling NetworkHDC
Wikipedia pathwaysHDC
Orthology - Evolution
OrthoDB3067
GeneTree (enSembl)ENSG00000140287
Phylogenetic Trees/Animal Genes : TreeFamHDC
HOGENOMP19113
Homologs : HomoloGeneHDC
Homology/Alignments : Family Browser (UCSC)HDC
Gene fusions - Rearrangements
Fusion : QuiverHDC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHDC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HDC
dbVarHDC
ClinVarHDC
MonarchHDC
1000_GenomesHDC 
Exome Variant ServerHDC
GNOMAD BrowserENSG00000140287
Varsome BrowserHDC
Genetic variants : HAPMAP3067
Genomic Variants (DGV)HDC [DGVbeta]
DECIPHERHDC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHDC 
Mutations
ICGC Data PortalHDC 
TCGA Data PortalHDC 
Broad Tumor PortalHDC
OASIS PortalHDC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHDC  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHDC
Mutations and Diseases : HGMDHDC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HDC
DgiDB (Drug Gene Interaction Database)HDC
DoCM (Curated mutations)HDC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HDC (select a term)
intoGenHDC
Cancer3DHDC(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137580    142704   
Orphanet
DisGeNETHDC
MedgenHDC
Genetic Testing Registry HDC
NextProtP19113 [Medical]
TSGene3067
GENETestsHDC
Target ValidationHDC
Huge Navigator HDC [HugePedia]
snp3D : Map Gene to Disease3067
BioCentury BCIQHDC
ClinGenHDC
Clinical trials, drugs, therapy
Protein Interactions : CTD3067
Pharm GKB GenePA29233
Clinical trialHDC
Miscellaneous
canSAR (ICR)HDC (select the gene name)
HarmonizomeHDC
DataMed IndexHDC
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHDC
EVEXHDC
GoPubMedHDC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 14 14:14:06 CEST 2020

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.