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HDGF (heparin binding growth factor)

Identity

Alias (NCBI)HMG1L2
HGNC (Hugo) HDGF
HGNC Alias symbHMG1L2
HGNC Alias namehigh-mobility group protein 1-like
HGNC Previous namehepatoma-derived growth factor (high-mobility group protein 1-like)
 hepatoma derived growth factor
LocusID (NCBI) 3068
Atlas_Id 40809
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 156742109 and ends at 156751675 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FBXW2 (9q33.2) / HDGF (1q23.1)HDGF (1q23.1) / ANKRD40 (17q21.33)HDGF (1q23.1) / FOXRED1 (11q24.2)
HDGF (1q23.1) / HDGF (1q23.1)HDGF (1q23.1) / S100A10 (1q21.3)RPS13 (11p15.1) / HDGF (1q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HDGF   4856
Cards
Entrez_Gene (NCBI)HDGF    heparin binding growth factor
AliasesHMG1L2
GeneCards (Weizmann)HDGF
Ensembl hg19 (Hinxton)ENSG00000143321 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143321 [Gene_View]  ENSG00000143321 [Sequence]  chr1:156742109-156751675 [Contig_View]  HDGF [Vega]
ICGC DataPortalENSG00000143321
TCGA cBioPortalHDGF
AceView (NCBI)HDGF
Genatlas (Paris)HDGF
SOURCE (Princeton)HDGF
Genetics Home Reference (NIH)HDGF
Genomic and cartography
GoldenPath hg38 (UCSC)HDGF  -     chr1:156742109-156751675 -  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HDGF  -     1q23.1   [Description]    (hg19-Feb_2009)
GoldenPathHDGF - 1q23.1 [CytoView hg19]  HDGF - 1q23.1 [CytoView hg38]
ImmunoBaseENSG00000143321
Genome Data Viewer NCBIHDGF [Mapview hg19]  
OMIM600339   
Gene and transcription
Genbank (Entrez)AK096411 AK292325 AK298342 AK304468 AK315514
RefSeq transcript (Entrez)NM_001126050 NM_001126051 NM_001319186 NM_001319187 NM_001319188 NM_004494
Consensus coding sequences : CCDS (NCBI)HDGF
Gene ExpressionHDGF [ NCBI-GEO ]   HDGF [ EBI - ARRAY_EXPRESS ]   HDGF [ SEEK ]   HDGF [ MEM ]
Gene Expression Viewer (FireBrowse)HDGF [ Firebrowse - Broad ]
GenevisibleExpression of HDGF in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3068
GTEX Portal (Tissue expression)HDGF
Human Protein AtlasENSG00000143321-HDGF [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51858   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51858  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51858
PhosPhoSitePlusP51858
Domaine pattern : Prosite (Expaxy)PWWP (PS50812)   
Domains : Interpro (EBI)HDGF-rel_PWWP    PWWP_dom   
Domain families : Pfam (Sanger)PWWP (PF00855)   
Domain families : Pfam (NCBI)pfam00855   
Domain families : Smart (EMBL)PWWP (SM00293)  
Conserved Domain (NCBI)HDGF
PDB (RSDB)1RI0    2NLU   
PDB Europe1RI0    2NLU   
PDB (PDBSum)1RI0    2NLU   
PDB (IMB)1RI0    2NLU   
Structural Biology KnowledgeBase1RI0    2NLU   
SCOP (Structural Classification of Proteins)1RI0    2NLU   
CATH (Classification of proteins structures)1RI0    2NLU   
SuperfamilyP51858
AlphaFold pdb e-kbP51858   
Human Protein Atlas [tissue]ENSG00000143321-HDGF [tissue]
HPRD02079
Protein Interaction databases
DIP (DOE-UCLA)P51858
IntAct (EBI)P51858
BioGRIDHDGF
STRING (EMBL)HDGF
ZODIACHDGF
Ontologies - Pathways
QuickGOP51858
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nucleotide binding  transcription corepressor binding  double-stranded DNA binding  transcription coregulator activity  transcription corepressor activity  RNA binding  extracellular region  extracellular space  nucleus  nucleoplasm  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  signal transduction  growth factor activity  heparin binding  transcription repressor complex  IRE1-mediated unfolded protein response  collagen-containing extracellular matrix  cellular response to interleukin-7  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nucleotide binding  transcription corepressor binding  double-stranded DNA binding  transcription coregulator activity  transcription corepressor activity  RNA binding  extracellular region  extracellular space  nucleus  nucleoplasm  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  signal transduction  growth factor activity  heparin binding  transcription repressor complex  IRE1-mediated unfolded protein response  collagen-containing extracellular matrix  cellular response to interleukin-7  
NDEx NetworkHDGF
Atlas of Cancer Signalling NetworkHDGF
Wikipedia pathwaysHDGF
Orthology - Evolution
OrthoDB3068
GeneTree (enSembl)ENSG00000143321
Phylogenetic Trees/Animal Genes : TreeFamHDGF
Homologs : HomoloGeneHDGF
Homology/Alignments : Family Browser (UCSC)HDGF
Gene fusions - Rearrangements
Fusion : MitelmanHDGF/S100A10 [1q23.1/1q21.3]  
Fusion : QuiverHDGF
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHDGF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HDGF
dbVarHDGF
ClinVarHDGF
MonarchHDGF
1000_GenomesHDGF 
Exome Variant ServerHDGF
GNOMAD BrowserENSG00000143321
Varsome BrowserHDGF
ACMGHDGF variants
VarityP51858
Genomic Variants (DGV)HDGF [DGVbeta]
DECIPHERHDGF [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHDGF 
Mutations
ICGC Data PortalHDGF 
TCGA Data PortalHDGF 
Broad Tumor PortalHDGF
OASIS PortalHDGF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHDGF  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHDGF
Mutations and Diseases : HGMDHDGF
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHDGF
DgiDB (Drug Gene Interaction Database)HDGF
DoCM (Curated mutations)HDGF
CIViC (Clinical Interpretations of Variants in Cancer)HDGF
Cancer3DHDGF
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600339   
Orphanet
DisGeNETHDGF
MedgenHDGF
Genetic Testing Registry HDGF
NextProtP51858 [Medical]
GENETestsHDGF
Target ValidationHDGF
Huge Navigator HDGF [HugePedia]
ClinGenHDGF
Clinical trials, drugs, therapy
MyCancerGenomeHDGF
Protein Interactions : CTDHDGF
Pharm GKB GenePA29234
PharosP51858
Clinical trialHDGF
Miscellaneous
canSAR (ICR)HDGF
HarmonizomeHDGF
DataMed IndexHDGF
Probes
Litterature
PubMed127 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHDGF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:12:11 CEST 2021

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