Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HDHD2 (haloacid dehalogenase like hydrolase domain containing 2)

Identity

Alias_nameshaloacid dehalogenase-like hydrolase domain containing 2
Alias_symbol (synonym)DKFZP564D1378
Other alias3110052N05Rik
HEL-S-301
HGNC (Hugo) HDHD2
LocusID (NCBI) 84064
Atlas_Id 54354
Location 18q21.1  [Link to chromosome band 18q21]
Location_base_pair Starts at 47107402 and ends at 47150520 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APLP2 (11q24.3) / HDHD2 (18q21.1)HDHD2 (18q21.1) / SNF8 (17q21.32)IER3IP1 (18q21.1) / HDHD2 (18q21.1)
SHISA6 (17p12) / HDHD2 (18q21.1)HDHD2 18q21.1 / SNF8 17q21.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HDHD2   25364
Cards
Entrez_Gene (NCBI)HDHD2  84064  haloacid dehalogenase like hydrolase domain containing 2
Aliases3110052N05Rik; HEL-S-301
GeneCards (Weizmann)HDHD2
Ensembl hg19 (Hinxton)ENSG00000167220 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167220 [Gene_View]  chr18:47107402-47150520 [Contig_View]  HDHD2 [Vega]
ICGC DataPortalENSG00000167220
TCGA cBioPortalHDHD2
AceView (NCBI)HDHD2
Genatlas (Paris)HDHD2
WikiGenes84064
SOURCE (Princeton)HDHD2
Genetics Home Reference (NIH)HDHD2
Genomic and cartography
GoldenPath hg38 (UCSC)HDHD2  -     chr18:47107402-47150520 -  18q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HDHD2  -     18q21.1   [Description]    (hg19-Feb_2009)
EnsemblHDHD2 - 18q21.1 [CytoView hg19]  HDHD2 - 18q21.1 [CytoView hg38]
Mapping of homologs : NCBIHDHD2 [Mapview hg19]  HDHD2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA206788 AK054590 AK292098 AL136681 AM393480
RefSeq transcript (Entrez)NM_001318765 NM_032124
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HDHD2
Cluster EST : UnigeneHs.465041 [ NCBI ]
CGAP (NCI)Hs.465041
Alternative Splicing GalleryENSG00000167220
Gene ExpressionHDHD2 [ NCBI-GEO ]   HDHD2 [ EBI - ARRAY_EXPRESS ]   HDHD2 [ SEEK ]   HDHD2 [ MEM ]
Gene Expression Viewer (FireBrowse)HDHD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84064
GTEX Portal (Tissue expression)HDHD2
Human Protein AtlasENSG00000167220-HDHD2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0R4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0R4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0R4
Splice isoforms : SwissVarQ9H0R4
PhosPhoSitePlusQ9H0R4
Domains : Interpro (EBI)HAD-like_dom    HAD-SF_hydro_IIA    HAD-SF_hydro_IIA_hyp2    NPhePase-like_dom   
Domain families : Pfam (Sanger)Hydrolase_6 (PF13344)   
Domain families : Pfam (NCBI)pfam13344   
Conserved Domain (NCBI)HDHD2
DMDM Disease mutations84064
Blocks (Seattle)HDHD2
PDB (SRS)3HLT   
PDB (PDBSum)3HLT   
PDB (IMB)3HLT   
PDB (RSDB)3HLT   
Structural Biology KnowledgeBase3HLT   
SCOP (Structural Classification of Proteins)3HLT   
CATH (Classification of proteins structures)3HLT   
SuperfamilyQ9H0R4
Human Protein Atlas [tissue]ENSG00000167220-HDHD2 [tissue]
Peptide AtlasQ9H0R4
HPRD13640
IPIIPI00783874   IPI00644472   
Protein Interaction databases
DIP (DOE-UCLA)Q9H0R4
IntAct (EBI)Q9H0R4
FunCoupENSG00000167220
BioGRIDHDHD2
STRING (EMBL)HDHD2
ZODIACHDHD2
Ontologies - Pathways
QuickGOQ9H0R4
Ontology : AmiGOprotein binding  biological_process  dephosphorylation  phosphatase activity  enzyme binding  metal ion binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  biological_process  dephosphorylation  phosphatase activity  enzyme binding  metal ion binding  extracellular exosome  
NDEx NetworkHDHD2
Atlas of Cancer Signalling NetworkHDHD2
Wikipedia pathwaysHDHD2
Orthology - Evolution
OrthoDB84064
GeneTree (enSembl)ENSG00000167220
Phylogenetic Trees/Animal Genes : TreeFamHDHD2
HOVERGENQ9H0R4
HOGENOMQ9H0R4
Homologs : HomoloGeneHDHD2
Homology/Alignments : Family Browser (UCSC)HDHD2
Gene fusions - Rearrangements
Fusion : MitelmanHDHD2/SNF8 [18q21.1/17q21.32]  
Fusion : MitelmanIER3IP1/HDHD2 [18q21.1/18q21.1]  [del(18)(q21)]  [del(18)(q21q21)]  
Fusion: TCGA_MDACCHDHD2 18q21.1 SNF8 17q21.32 BRCA
Tumor Fusion PortalHDHD2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHDHD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HDHD2
dbVarHDHD2
ClinVarHDHD2
1000_GenomesHDHD2 
Exome Variant ServerHDHD2
ExAC (Exome Aggregation Consortium)ENSG00000167220
GNOMAD BrowserENSG00000167220
Genetic variants : HAPMAP84064
Genomic Variants (DGV)HDHD2 [DGVbeta]
DECIPHERHDHD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHDHD2 
Mutations
ICGC Data PortalHDHD2 
TCGA Data PortalHDHD2 
Broad Tumor PortalHDHD2
OASIS PortalHDHD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHDHD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHDHD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HDHD2
DgiDB (Drug Gene Interaction Database)HDHD2
DoCM (Curated mutations)HDHD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HDHD2 (select a term)
intoGenHDHD2
Cancer3DHDHD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETHDHD2
MedgenHDHD2
Genetic Testing Registry HDHD2
NextProtQ9H0R4 [Medical]
TSGene84064
GENETestsHDHD2
Target ValidationHDHD2
Huge Navigator HDHD2 [HugePedia]
snp3D : Map Gene to Disease84064
BioCentury BCIQHDHD2
ClinGenHDHD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84064
Chemical/Pharm GKB GenePA134952019
Clinical trialHDHD2
Miscellaneous
canSAR (ICR)HDHD2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHDHD2
EVEXHDHD2
GoPubMedHDHD2
iHOPHDHD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:15:54 CET 2017

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