Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HEBP1 (heme binding protein 1)

Identity

Alias (NCBI)HBP
HEBP
HGNC (Hugo) HEBP1
HGNC Alias symbHEBP
HBP
LocusID (NCBI) 50865
Atlas_Id 64225
Location 12p13.1  [Link to chromosome band 12p13]
Location_base_pair Starts at 12974865 and ends at 13000309 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HEBP1 (12p13.1) / CREBL2 (12p13.2)HEBP1 (12p13.1) / ZBTB46 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  HEBP1/CREBL2 (12p13)
t(12;20)(p13;q13) HEBP1/ZBTB46


External links

Nomenclature
HGNC (Hugo)HEBP1   17176
Cards
Entrez_Gene (NCBI)HEBP1  50865  heme binding protein 1
AliasesHBP; HEBP
GeneCards (Weizmann)HEBP1
Ensembl hg19 (Hinxton)ENSG00000013583 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000013583 [Gene_View]  ENSG00000013583 [Sequence]  chr12:12974865-13000309 [Contig_View]  HEBP1 [Vega]
ICGC DataPortalENSG00000013583
TCGA cBioPortalHEBP1
AceView (NCBI)HEBP1
Genatlas (Paris)HEBP1
WikiGenes50865
SOURCE (Princeton)HEBP1
Genetics Home Reference (NIH)HEBP1
Genomic and cartography
GoldenPath hg38 (UCSC)HEBP1  -     chr12:12974865-13000309 -  12p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HEBP1  -     12p13.1   [Description]    (hg19-Feb_2009)
GoldenPathHEBP1 - 12p13.1 [CytoView hg19]  HEBP1 - 12p13.1 [CytoView hg38]
ImmunoBaseENSG00000013583
genome Data Viewer NCBIHEBP1 [Mapview hg19]  
OMIM605826   
Gene and transcription
Genbank (Entrez)AA699304 AF117615 AF167473 AK289877 AW452041
RefSeq transcript (Entrez)NM_015987
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HEBP1
Alternative Splicing GalleryENSG00000013583
Gene ExpressionHEBP1 [ NCBI-GEO ]   HEBP1 [ EBI - ARRAY_EXPRESS ]   HEBP1 [ SEEK ]   HEBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)HEBP1 [ Firebrowse - Broad ]
GenevisibleExpression of HEBP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50865
GTEX Portal (Tissue expression)HEBP1
Human Protein AtlasENSG00000013583-HEBP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRV9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRV9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRV9
Splice isoforms : SwissVarQ9NRV9
PhosPhoSitePlusQ9NRV9
Domains : Interpro (EBI)Reg_factor_effector_dom_sf    SOUL_haem-bd   
Domain families : Pfam (Sanger)SOUL (PF04832)   
Domain families : Pfam (NCBI)pfam04832   
Conserved Domain (NCBI)HEBP1
DMDM Disease mutations50865
Blocks (Seattle)HEBP1
SuperfamilyQ9NRV9
Human Protein Atlas [tissue]ENSG00000013583-HEBP1 [tissue]
Peptide AtlasQ9NRV9
HPRD16162
IPIIPI00148063   IPI01015014   IPI01014549   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRV9
IntAct (EBI)Q9NRV9
FunCoupENSG00000013583
BioGRIDHEBP1
STRING (EMBL)HEBP1
ZODIACHEBP1
Ontologies - Pathways
QuickGOQ9NRV9
Ontology : AmiGOextracellular region  cytoplasm  G protein-coupled receptor signaling pathway  circadian rhythm  heme binding  heme binding  extracellular exosome  
Ontology : EGO-EBIextracellular region  cytoplasm  G protein-coupled receptor signaling pathway  circadian rhythm  heme binding  heme binding  extracellular exosome  
NDEx NetworkHEBP1
Atlas of Cancer Signalling NetworkHEBP1
Wikipedia pathwaysHEBP1
Orthology - Evolution
OrthoDB50865
GeneTree (enSembl)ENSG00000013583
Phylogenetic Trees/Animal Genes : TreeFamHEBP1
HOGENOMQ9NRV9
Homologs : HomoloGeneHEBP1
Homology/Alignments : Family Browser (UCSC)HEBP1
Gene fusions - Rearrangements
Fusion : QuiverHEBP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHEBP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HEBP1
dbVarHEBP1
ClinVarHEBP1
1000_GenomesHEBP1 
Exome Variant ServerHEBP1
GNOMAD BrowserENSG00000013583
Varsome BrowserHEBP1
Genetic variants : HAPMAP50865
Genomic Variants (DGV)HEBP1 [DGVbeta]
DECIPHERHEBP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHEBP1 
Mutations
ICGC Data PortalHEBP1 
TCGA Data PortalHEBP1 
Broad Tumor PortalHEBP1
OASIS PortalHEBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHEBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHEBP1
Mutations and Diseases : HGMDHEBP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HEBP1
DgiDB (Drug Gene Interaction Database)HEBP1
DoCM (Curated mutations)HEBP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HEBP1 (select a term)
intoGenHEBP1
Cancer3DHEBP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605826   
Orphanet
DisGeNETHEBP1
MedgenHEBP1
Genetic Testing Registry HEBP1
NextProtQ9NRV9 [Medical]
TSGene50865
GENETestsHEBP1
Target ValidationHEBP1
Huge Navigator HEBP1 [HugePedia]
snp3D : Map Gene to Disease50865
BioCentury BCIQHEBP1
ClinGenHEBP1
Clinical trials, drugs, therapy
Protein Interactions : CTD50865
Pharm GKB GenePA29236
Clinical trialHEBP1
Miscellaneous
canSAR (ICR)HEBP1 (select the gene name)
HarmonizomeHEBP1
DataMed IndexHEBP1
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHEBP1
EVEXHEBP1
GoPubMedHEBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:58:10 CEST 2020

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