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HECTD3 (HECT domain E3 ubiquitin protein ligase 3)

Identity

Alias_namesHECT domain containing E3 ubiquitin protein ligase 3
Alias_symbol (synonym)FLJ21156
Other alias-
HGNC (Hugo) HECTD3
LocusID (NCBI) 79654
Atlas_Id 47202
Location 1p34.1  [Link to chromosome band 1p34]
Location_base_pair Starts at 45002548 and ends at 45011355 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HECTD3   26117
Cards
Entrez_Gene (NCBI)HECTD3  79654  HECT domain E3 ubiquitin protein ligase 3
Aliases
GeneCards (Weizmann)HECTD3
Ensembl hg19 (Hinxton)ENSG00000126107 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126107 [Gene_View]  chr1:45002548-45011355 [Contig_View]  HECTD3 [Vega]
ICGC DataPortalENSG00000126107
TCGA cBioPortalHECTD3
AceView (NCBI)HECTD3
Genatlas (Paris)HECTD3
WikiGenes79654
SOURCE (Princeton)HECTD3
Genetics Home Reference (NIH)HECTD3
Genomic and cartography
GoldenPath hg38 (UCSC)HECTD3  -     chr1:45002548-45011355 -  1p34.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HECTD3  -     1p34.1   [Description]    (hg19-Feb_2009)
EnsemblHECTD3 - 1p34.1 [CytoView hg19]  HECTD3 - 1p34.1 [CytoView hg38]
Mapping of homologs : NCBIHECTD3 [Mapview hg19]  HECTD3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA001245 AK056545 AK056873 AK091583 AK096462
RefSeq transcript (Entrez)NM_024602
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HECTD3
Cluster EST : UnigeneHs.525084 [ NCBI ]
CGAP (NCI)Hs.525084
Alternative Splicing GalleryENSG00000126107
Gene ExpressionHECTD3 [ NCBI-GEO ]   HECTD3 [ EBI - ARRAY_EXPRESS ]   HECTD3 [ SEEK ]   HECTD3 [ MEM ]
Gene Expression Viewer (FireBrowse)HECTD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79654
GTEX Portal (Tissue expression)HECTD3
Human Protein AtlasENSG00000126107-HECTD3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T447   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T447  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T447
Splice isoforms : SwissVarQ5T447
Catalytic activity : Enzyme2.3.2.26 [ Enzyme-Expasy ]   2.3.2.262.3.2.26 [ IntEnz-EBI ]   2.3.2.26 [ BRENDA ]   2.3.2.26 [ KEGG ]   
PhosPhoSitePlusQ5T447
Domaine pattern : Prosite (Expaxy)DOC (PS51284)    HECT (PS50237)   
Domains : Interpro (EBI)APC_su10/DOC_dom    Galactose-bd-like    HECT_dom   
Domain families : Pfam (Sanger)ANAPC10 (PF03256)    HECT (PF00632)   
Domain families : Pfam (NCBI)pfam03256    pfam00632   
Domain families : Smart (EMBL)APC10 (SM01337)  HECTc (SM00119)  
Conserved Domain (NCBI)HECTD3
DMDM Disease mutations79654
Blocks (Seattle)HECTD3
SuperfamilyQ5T447
Human Protein Atlas [tissue]ENSG00000126107-HECTD3 [tissue]
Peptide AtlasQ5T447
HPRD13383
IPIIPI00456642   IPI00941376   
Protein Interaction databases
DIP (DOE-UCLA)Q5T447
IntAct (EBI)Q5T447
FunCoupENSG00000126107
BioGRIDHECTD3
STRING (EMBL)HECTD3
ZODIACHECTD3
Ontologies - Pathways
QuickGOQ5T447
Ontology : AmiGOubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  protein ubiquitination  syntaxin binding  proteasome-mediated ubiquitin-dependent protein catabolic process  perinuclear region of cytoplasm  
Ontology : EGO-EBIubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  protein ubiquitination  syntaxin binding  proteasome-mediated ubiquitin-dependent protein catabolic process  perinuclear region of cytoplasm  
NDEx NetworkHECTD3
Atlas of Cancer Signalling NetworkHECTD3
Wikipedia pathwaysHECTD3
Orthology - Evolution
OrthoDB79654
GeneTree (enSembl)ENSG00000126107
Phylogenetic Trees/Animal Genes : TreeFamHECTD3
HOVERGENQ5T447
HOGENOMQ5T447
Homologs : HomoloGeneHECTD3
Homology/Alignments : Family Browser (UCSC)HECTD3
Gene fusions - Rearrangements
Tumor Fusion PortalHECTD3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHECTD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HECTD3
dbVarHECTD3
ClinVarHECTD3
1000_GenomesHECTD3 
Exome Variant ServerHECTD3
ExAC (Exome Aggregation Consortium)ENSG00000126107
GNOMAD BrowserENSG00000126107
Genetic variants : HAPMAP79654
Genomic Variants (DGV)HECTD3 [DGVbeta]
DECIPHERHECTD3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHECTD3 
Mutations
ICGC Data PortalHECTD3 
TCGA Data PortalHECTD3 
Broad Tumor PortalHECTD3
OASIS PortalHECTD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHECTD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHECTD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HECTD3
DgiDB (Drug Gene Interaction Database)HECTD3
DoCM (Curated mutations)HECTD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HECTD3 (select a term)
intoGenHECTD3
Cancer3DHECTD3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETHECTD3
MedgenHECTD3
Genetic Testing Registry HECTD3
NextProtQ5T447 [Medical]
TSGene79654
GENETestsHECTD3
Target ValidationHECTD3
Huge Navigator HECTD3 [HugePedia]
snp3D : Map Gene to Disease79654
BioCentury BCIQHECTD3
ClinGenHECTD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79654
Chemical/Pharm GKB GenePA142671698
Clinical trialHECTD3
Miscellaneous
canSAR (ICR)HECTD3 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHECTD3
EVEXHECTD3
GoPubMedHECTD3
iHOPHECTD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:39:24 CET 2017

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