Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5)

Identity

Alias_nameshect domain and RLD 5
Alias_symbol (synonym)CEB1
Other aliasCEBP1
HGNC (Hugo) HERC5
LocusID (NCBI) 51191
Atlas_Id 46681
Location 4q22.1  [Link to chromosome band 4q22]
Location_base_pair Starts at 88457117 and ends at 88506168 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HERC5   24368
Cards
Entrez_Gene (NCBI)HERC5  51191  HECT and RLD domain containing E3 ubiquitin protein ligase 5
AliasesCEB1; CEBP1
GeneCards (Weizmann)HERC5
Ensembl hg19 (Hinxton)ENSG00000138646 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138646 [Gene_View]  chr4:88457117-88506168 [Contig_View]  HERC5 [Vega]
ICGC DataPortalENSG00000138646
TCGA cBioPortalHERC5
AceView (NCBI)HERC5
Genatlas (Paris)HERC5
WikiGenes51191
SOURCE (Princeton)HERC5
Genetics Home Reference (NIH)HERC5
Genomic and cartography
GoldenPath hg38 (UCSC)HERC5  -     chr4:88457117-88506168 +  4q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HERC5  -     4q22.1   [Description]    (hg19-Feb_2009)
EnsemblHERC5 - 4q22.1 [CytoView hg19]  HERC5 - 4q22.1 [CytoView hg38]
Mapping of homologs : NCBIHERC5 [Mapview hg19]  HERC5 [Mapview hg38]
OMIM608242   
Gene and transcription
Genbank (Entrez)AB027289 AI336946 AK093155 AK301756 AK302142
RefSeq transcript (Entrez)NM_016323
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HERC5
Cluster EST : UnigeneHs.26663 [ NCBI ]
CGAP (NCI)Hs.26663
Alternative Splicing GalleryENSG00000138646
Gene ExpressionHERC5 [ NCBI-GEO ]   HERC5 [ EBI - ARRAY_EXPRESS ]   HERC5 [ SEEK ]   HERC5 [ MEM ]
Gene Expression Viewer (FireBrowse)HERC5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51191
GTEX Portal (Tissue expression)HERC5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UII4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UII4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UII4
Splice isoforms : SwissVarQ9UII4
Catalytic activity : Enzyme2.3.2.- [ Enzyme-Expasy ]   2.3.2.-2.3.2.- [ IntEnz-EBI ]   2.3.2.- [ BRENDA ]   2.3.2.- [ KEGG ]   
PhosPhoSitePlusQ9UII4
Domaine pattern : Prosite (Expaxy)HECT (PS50237)    RCC1_2 (PS00626)    RCC1_3 (PS50012)   
Domains : Interpro (EBI)HECT_dom    RCC1/BLIP-II    Reg_chr_condens   
Domain families : Pfam (Sanger)HECT (PF00632)    RCC1 (PF00415)   
Domain families : Pfam (NCBI)pfam00632    pfam00415   
Domain families : Smart (EMBL)HECTc (SM00119)  
Conserved Domain (NCBI)HERC5
DMDM Disease mutations51191
Blocks (Seattle)HERC5
SuperfamilyQ9UII4
Human Protein AtlasENSG00000138646
Peptide AtlasQ9UII4
HPRD10502
IPIIPI00008821   IPI00896511   
Protein Interaction databases
DIP (DOE-UCLA)Q9UII4
IntAct (EBI)Q9UII4
FunCoupENSG00000138646
BioGRIDHERC5
STRING (EMBL)HERC5
ZODIACHERC5
Ontologies - Pathways
QuickGOQ9UII4
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  protein polyubiquitination  RNA binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytosol  ISG15-protein conjugation  negative regulation of type I interferon production  ISG15 transferase activity  innate immune response  perinuclear region of cytoplasm  regulation of defense response to virus  defense response to virus  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  protein polyubiquitination  RNA binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytosol  ISG15-protein conjugation  negative regulation of type I interferon production  ISG15 transferase activity  innate immune response  perinuclear region of cytoplasm  regulation of defense response to virus  defense response to virus  
NDEx NetworkHERC5
Atlas of Cancer Signalling NetworkHERC5
Wikipedia pathwaysHERC5
Orthology - Evolution
OrthoDB51191
GeneTree (enSembl)ENSG00000138646
Phylogenetic Trees/Animal Genes : TreeFamHERC5
HOVERGENQ9UII4
HOGENOMQ9UII4
Homologs : HomoloGeneHERC5
Homology/Alignments : Family Browser (UCSC)HERC5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHERC5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HERC5
dbVarHERC5
ClinVarHERC5
1000_GenomesHERC5 
Exome Variant ServerHERC5
ExAC (Exome Aggregation Consortium)HERC5 (select the gene name)
Genetic variants : HAPMAP51191
Genomic Variants (DGV)HERC5 [DGVbeta]
DECIPHERHERC5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHERC5 
Mutations
ICGC Data PortalHERC5 
TCGA Data PortalHERC5 
Broad Tumor PortalHERC5
OASIS PortalHERC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHERC5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHERC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HERC5
DgiDB (Drug Gene Interaction Database)HERC5
DoCM (Curated mutations)HERC5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HERC5 (select a term)
intoGenHERC5
Cancer3DHERC5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608242   
Orphanet
MedgenHERC5
Genetic Testing Registry HERC5
NextProtQ9UII4 [Medical]
TSGene51191
GENETestsHERC5
Target ValidationHERC5
Huge Navigator HERC5 [HugePedia]
snp3D : Map Gene to Disease51191
BioCentury BCIQHERC5
ClinGenHERC5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51191
Chemical/Pharm GKB GenePA134973940
Clinical trialHERC5
Miscellaneous
canSAR (ICR)HERC5 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHERC5
EVEXHERC5
GoPubMedHERC5
iHOPHERC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:02:53 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.