Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HES3 (hes family bHLH transcription factor 3)

Identity

Other aliasbHLHb43
HGNC (Hugo) HES3
LocusID (NCBI) 390992
Atlas_Id 56659
Location 1p36.31  [Link to chromosome band 1p36]
Location_base_pair Starts at 6304252 and ends at 6305638 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HES3   26226
Cards
Entrez_Gene (NCBI)HES3  390992  hes family bHLH transcription factor 3
AliasesbHLHb43
GeneCards (Weizmann)HES3
Ensembl hg19 (Hinxton) [Gene_View]  chr1:6304252-6305638 [Contig_View]  HES3 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr1:6304252-6305638 [Contig_View]  HES3 [Vega]
TCGA cBioPortalHES3
AceView (NCBI)HES3
Genatlas (Paris)HES3
WikiGenes390992
SOURCE (Princeton)HES3
Genetics Home Reference (NIH)HES3
Genomic and cartography
GoldenPath hg19 (UCSC)HES3  -     chr1:6304252-6305638 +  1p36.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HES3  -     1p36.31   [Description]    (hg38-Dec_2013)
EnsemblHES3 - 1p36.31 [CytoView hg19]  HES3 - 1p36.31 [CytoView hg38]
Mapping of homologs : NCBIHES3 [Mapview hg19]  HES3 [Mapview hg38]
OMIM609971   
Gene and transcription
Genbank (Entrez)BC156115 BC156912 CN370501 CN413592 CX755241
RefSeq transcript (Entrez)NM_001024598
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HES3
Cluster EST : UnigeneHs.532677 [ NCBI ]
CGAP (NCI)Hs.532677
Gene ExpressionHES3 [ NCBI-GEO ]   HES3 [ EBI - ARRAY_EXPRESS ]   HES3 [ SEEK ]   HES3 [ MEM ]
Gene Expression Viewer (FireBrowse)HES3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)390992
GTEX Portal (Tissue expression)HES3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TGS1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TGS1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TGS1
Splice isoforms : SwissVarQ5TGS1
PhosPhoSitePlusQ5TGS1
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)HES3
DMDM Disease mutations390992
Blocks (Seattle)HES3
SuperfamilyQ5TGS1
Peptide AtlasQ5TGS1
IPIIPI00376185   
Protein Interaction databases
DIP (DOE-UCLA)Q5TGS1
IntAct (EBI)Q5TGS1
BioGRIDHES3
STRING (EMBL)HES3
ZODIACHES3
Ontologies - Pathways
QuickGOQ5TGS1
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  in utero embryonic development  DNA binding  nucleus  transcription, DNA-templated  transcription factor binding  midbrain-hindbrain boundary morphogenesis  oculomotor nerve development  trochlear nerve development  hindbrain morphogenesis  midbrain development  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of timing of neuron differentiation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  in utero embryonic development  DNA binding  nucleus  transcription, DNA-templated  transcription factor binding  midbrain-hindbrain boundary morphogenesis  oculomotor nerve development  trochlear nerve development  hindbrain morphogenesis  midbrain development  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of timing of neuron differentiation  
NDEx NetworkHES3
Atlas of Cancer Signalling NetworkHES3
Wikipedia pathwaysHES3
Orthology - Evolution
OrthoDB390992
Phylogenetic Trees/Animal Genes : TreeFamHES3
HOVERGENQ5TGS1
HOGENOMQ5TGS1
Homologs : HomoloGeneHES3
Homology/Alignments : Family Browser (UCSC)HES3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHES3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HES3
dbVarHES3
ClinVarHES3
1000_GenomesHES3 
Exome Variant ServerHES3
ExAC (Exome Aggregation Consortium)HES3 (select the gene name)
Genetic variants : HAPMAP390992
Genomic Variants (DGV)HES3 [DGVbeta]
DECIPHER (Syndromes)1:6304252-6305638  
CONAN: Copy Number AnalysisHES3 
Mutations
ICGC Data PortalHES3 
TCGA Data PortalHES3 
Broad Tumor PortalHES3
OASIS PortalHES3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHES3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHES3
BioMutasearch HES3
DgiDB (Drug Gene Interaction Database)HES3
DoCM (Curated mutations)HES3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HES3 (select a term)
intoGenHES3
Cancer3DHES3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609971   
Orphanet
MedgenHES3
Genetic Testing Registry HES3
NextProtQ5TGS1 [Medical]
TSGene390992
GENETestsHES3
Huge Navigator HES3 [HugePedia]
snp3D : Map Gene to Disease390992
BioCentury BCIQHES3
ClinGenHES3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD390992
Chemical/Pharm GKB GenePA142671692
Clinical trialHES3
Miscellaneous
canSAR (ICR)HES3 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHES3
EVEXHES3
GoPubMedHES3
iHOPHES3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:03:37 CEST 2017

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