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HES4 (hes family bHLH transcription factor 4)

Identity

Alias_nameshairy and enhancer of split 4 (Drosophila)
Alias_symbol (synonym)bHLHb42
Other alias
HGNC (Hugo) HES4
LocusID (NCBI) 57801
Atlas_Id 47428
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 998964 and ends at 1000172 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HES4   24149
Cards
Entrez_Gene (NCBI)HES4  57801  hes family bHLH transcription factor 4
AliasesbHLHb42
GeneCards (Weizmann)HES4
Ensembl hg19 (Hinxton)ENSG00000188290 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188290 [Gene_View]  chr1:998964-1000172 [Contig_View]  HES4 [Vega]
ICGC DataPortalENSG00000188290
TCGA cBioPortalHES4
AceView (NCBI)HES4
Genatlas (Paris)HES4
WikiGenes57801
SOURCE (Princeton)HES4
Genetics Home Reference (NIH)HES4
Genomic and cartography
GoldenPath hg38 (UCSC)HES4  -     chr1:998964-1000172 -  1p36.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HES4  -     1p36.33   [Description]    (hg19-Feb_2009)
EnsemblHES4 - 1p36.33 [CytoView hg19]  HES4 - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBIHES4 [Mapview hg19]  HES4 [Mapview hg38]
OMIM608060   
Gene and transcription
Genbank (Entrez)AB048791 BC012351 BI757407 BM128269 BM713553
RefSeq transcript (Entrez)NM_001142467 NM_021170
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HES4
Cluster EST : UnigeneHs.154029 [ NCBI ]
CGAP (NCI)Hs.154029
Alternative Splicing GalleryENSG00000188290
Gene ExpressionHES4 [ NCBI-GEO ]   HES4 [ EBI - ARRAY_EXPRESS ]   HES4 [ SEEK ]   HES4 [ MEM ]
Gene Expression Viewer (FireBrowse)HES4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57801
GTEX Portal (Tissue expression)HES4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCC6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCC6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCC6
Splice isoforms : SwissVarQ9HCC6
PhosPhoSitePlusQ9HCC6
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)    ORANGE (PS51054)   
Domains : Interpro (EBI)bHLH_dom    Orange_dom   
Domain families : Pfam (Sanger)Hairy_orange (PF07527)    HLH (PF00010)   
Domain families : Pfam (NCBI)pfam07527    pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  ORANGE (SM00511)  
Conserved Domain (NCBI)HES4
DMDM Disease mutations57801
Blocks (Seattle)HES4
SuperfamilyQ9HCC6
Human Protein AtlasENSG00000188290
Peptide AtlasQ9HCC6
HPRD16273
IPIIPI00028151   IPI00966381   IPI00917954   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCC6
IntAct (EBI)Q9HCC6
FunCoupENSG00000188290
BioGRIDHES4
STRING (EMBL)HES4
ZODIACHES4
Ontologies - Pathways
QuickGOQ9HCC6
Ontology : AmiGODNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  nervous system development  transcription factor binding  cell differentiation  protein dimerization activity  
Ontology : EGO-EBIDNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  nervous system development  transcription factor binding  cell differentiation  protein dimerization activity  
NDEx NetworkHES4
Atlas of Cancer Signalling NetworkHES4
Wikipedia pathwaysHES4
Orthology - Evolution
OrthoDB57801
GeneTree (enSembl)ENSG00000188290
Phylogenetic Trees/Animal Genes : TreeFamHES4
HOVERGENQ9HCC6
HOGENOMQ9HCC6
Homologs : HomoloGeneHES4
Homology/Alignments : Family Browser (UCSC)HES4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHES4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HES4
dbVarHES4
ClinVarHES4
1000_GenomesHES4 
Exome Variant ServerHES4
ExAC (Exome Aggregation Consortium)HES4 (select the gene name)
Genetic variants : HAPMAP57801
Genomic Variants (DGV)HES4 [DGVbeta]
DECIPHERHES4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHES4 
Mutations
ICGC Data PortalHES4 
TCGA Data PortalHES4 
Broad Tumor PortalHES4
OASIS PortalHES4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHES4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHES4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HES4
DgiDB (Drug Gene Interaction Database)HES4
DoCM (Curated mutations)HES4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HES4 (select a term)
intoGenHES4
Cancer3DHES4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608060   
Orphanet
MedgenHES4
Genetic Testing Registry HES4
NextProtQ9HCC6 [Medical]
TSGene57801
GENETestsHES4
Huge Navigator HES4 [HugePedia]
snp3D : Map Gene to Disease57801
BioCentury BCIQHES4
ClinGenHES4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57801
Chemical/Pharm GKB GenePA134975318
Clinical trialHES4
Miscellaneous
canSAR (ICR)HES4 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHES4
EVEXHES4
GoPubMedHES4
iHOPHES4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:18:40 CEST 2017

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