Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HESX1 (HESX homeobox 1)

Identity

Other namesANF
CPHD5
RPX
HGNC (Hugo) HESX1
LocusID (NCBI) 8820
Atlas_Id 47304
Location 3p14.3
Location_base_pair Starts at 57231944 and ends at 57234280 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARHGEF3 (3p14.3) / HESX1 (3p14.3)HESX1 (3p14.3) / FAT3 (11q14.3)ARHGEF3 3p14.3 / HESX1 3p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HESX1   4877
Cards
Entrez_Gene (NCBI)HESX1  8820  HESX homeobox 1
GeneCards (Weizmann)HESX1
Ensembl hg19 (Hinxton)ENSG00000163666 [Gene_View]  chr3:57231944-57234280 [Contig_View]  HESX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163666 [Gene_View]  chr3:57231944-57234280 [Contig_View]  HESX1 [Vega]
ICGC DataPortalENSG00000163666
TCGA cBioPortalHESX1
AceView (NCBI)HESX1
Genatlas (Paris)HESX1
WikiGenes8820
SOURCE (Princeton)HESX1
Genomic and cartography
GoldenPath hg19 (UCSC)HESX1  -     chr3:57231944-57234280 -  3p14.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HESX1  -     3p14.3   [Description]    (hg38-Dec_2013)
EnsemblHESX1 - 3p14.3 [CytoView hg19]  HESX1 - 3p14.3 [CytoView hg38]
Mapping of homologs : NCBIHESX1 [Mapview hg19]  HESX1 [Mapview hg38]
OMIM182230   601802   
Gene and transcription
Genbank (Entrez)AI652412 BC069515 BC093979 BC112089 EU446670
RefSeq transcript (Entrez)NM_003865
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_008242 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)HESX1
Cluster EST : UnigeneHs.171980 [ NCBI ]
CGAP (NCI)Hs.171980
Alternative Splicing GalleryENSG00000163666
Gene ExpressionHESX1 [ NCBI-GEO ]   HESX1 [ EBI - ARRAY_EXPRESS ]   HESX1 [ SEEK ]   HESX1 [ MEM ]
Gene Expression Viewer (FireBrowse)HESX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8820
GTEX Portal (Tissue expression)HESX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBX0 (Uniprot)
NextProtQ9UBX0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBX0
Splice isoforms : SwissVarQ9UBX0 (Swissvar)
PhosPhoSitePlusQ9UBX0
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeodomain-like   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations8820
Blocks (Seattle)HESX1
PDB (SRS)2K40   
PDB (PDBSum)2K40   
PDB (IMB)2K40   
PDB (RSDB)2K40   
Structural Biology KnowledgeBase2K40   
SCOP (Structural Classification of Proteins)2K40   
CATH (Classification of proteins structures)2K40   
SuperfamilyQ9UBX0
Human Protein AtlasENSG00000163666
Peptide AtlasQ9UBX0
HPRD03482
IPIIPI00002815   IPI00796112   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBX0
IntAct (EBI)Q9UBX0
FunCoupENSG00000163666
BioGRIDHESX1
STRING (EMBL)HESX1
ZODIACHESX1
Ontologies - Pathways
QuickGOQ9UBX0
Ontology : AmiGODNA binding  chromatin binding  protein binding  nucleus  transcription, DNA-templated  brain development  protein C-terminus binding  otic vesicle formation  sequence-specific DNA binding  nose development  negative regulation of transcription, DNA-templated  protein N-terminus binding  forebrain morphogenesis  
Ontology : EGO-EBIDNA binding  chromatin binding  protein binding  nucleus  transcription, DNA-templated  brain development  protein C-terminus binding  otic vesicle formation  sequence-specific DNA binding  nose development  negative regulation of transcription, DNA-templated  protein N-terminus binding  forebrain morphogenesis  
NDEx Network
Atlas of Cancer Signalling NetworkHESX1
Wikipedia pathwaysHESX1
Orthology - Evolution
OrthoDB8820
GeneTree (enSembl)ENSG00000163666
Phylogenetic Trees/Animal Genes : TreeFamHESX1
Homologs : HomoloGeneHESX1
Homology/Alignments : Family Browser (UCSC)HESX1
Gene fusions - Rearrangements
Fusion: TCGAARHGEF3 3p14.3 HESX1 3p14.3 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerHESX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HESX1
dbVarHESX1
ClinVarHESX1
1000_GenomesHESX1 
Exome Variant ServerHESX1
ExAC (Exome Aggregation Consortium)HESX1 (select the gene name)
Genetic variants : HAPMAP8820
Genomic Variants (DGV)HESX1 [DGVbeta]
Mutations
ICGC Data PortalHESX1 
TCGA Data PortalHESX1 
Broad Tumor PortalHESX1
OASIS PortalHESX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHESX1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HESX1
DgiDB (Drug Gene Interaction Database)HESX1
DoCM (Curated mutations)HESX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HESX1 (select a term)
intoGenHESX1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:57231944-57234280  ENSG00000163666
CONAN: Copy Number AnalysisHESX1 
Mutations and Diseases : HGMDHESX1
OMIM182230    601802   
MedgenHESX1
Genetic Testing Registry HESX1
NextProtQ9UBX0 [Medical]
TSGene8820
GENETestsHESX1
Huge Navigator HESX1 [HugePedia]
snp3D : Map Gene to Disease8820
BioCentury BCIQHESX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8820
Chemical/Pharm GKB GenePA29255
Clinical trialHESX1
Miscellaneous
canSAR (ICR)HESX1 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHESX1
EVEXHESX1
GoPubMedHESX1
iHOPHESX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 18:49:00 CEST 2016

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