Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HEXIM1 (hexamethylene bis-acetamide inducible 1)

Identity

Alias_symbol (synonym)CLP-1
HIS1
MAQ1
EDG1
Other aliasCLP1
HGNC (Hugo) HEXIM1
LocusID (NCBI) 10614
Atlas_Id 43034
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 43224684 and ends at 43229468 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
H1FX (3q21.3) / HEXIM1 (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HEXIM1   24953
Cards
Entrez_Gene (NCBI)HEXIM1  10614  hexamethylene bis-acetamide inducible 1
AliasesCLP1; EDG1; HIS1; MAQ1
GeneCards (Weizmann)HEXIM1
Ensembl hg19 (Hinxton)ENSG00000186834 [Gene_View]  chr17:43224684-43229468 [Contig_View]  HEXIM1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186834 [Gene_View]  chr17:43224684-43229468 [Contig_View]  HEXIM1 [Vega]
ICGC DataPortalENSG00000186834
TCGA cBioPortalHEXIM1
AceView (NCBI)HEXIM1
Genatlas (Paris)HEXIM1
WikiGenes10614
SOURCE (Princeton)HEXIM1
Genetics Home Reference (NIH)HEXIM1
Genomic and cartography
GoldenPath hg19 (UCSC)HEXIM1  -     chr17:43224684-43229468 +  17q21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HEXIM1  -     17q21.31   [Description]    (hg38-Dec_2013)
EnsemblHEXIM1 - 17q21.31 [CytoView hg19]  HEXIM1 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIHEXIM1 [Mapview hg19]  HEXIM1 [Mapview hg38]
OMIM607328   
Gene and transcription
Genbank (Entrez)AB021179 AI092623 AK023624 AK313557 AL521530
RefSeq transcript (Entrez)NM_006460
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)HEXIM1
Cluster EST : UnigeneHs.745252 [ NCBI ]
CGAP (NCI)Hs.745252
Alternative Splicing GalleryENSG00000186834
Gene ExpressionHEXIM1 [ NCBI-GEO ]   HEXIM1 [ EBI - ARRAY_EXPRESS ]   HEXIM1 [ SEEK ]   HEXIM1 [ MEM ]
Gene Expression Viewer (FireBrowse)HEXIM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10614
GTEX Portal (Tissue expression)HEXIM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94992   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94992  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94992
Splice isoforms : SwissVarO94992
PhosPhoSitePlusO94992
Domains : Interpro (EBI)HEXIM   
Domain families : Pfam (Sanger)HEXIM (PF15313)   
Domain families : Pfam (NCBI)pfam15313   
Conserved Domain (NCBI)HEXIM1
DMDM Disease mutations10614
Blocks (Seattle)HEXIM1
PDB (SRS)2GD7    3S9G   
PDB (PDBSum)2GD7    3S9G   
PDB (IMB)2GD7    3S9G   
PDB (RSDB)2GD7    3S9G   
Structural Biology KnowledgeBase2GD7    3S9G   
SCOP (Structural Classification of Proteins)2GD7    3S9G   
CATH (Classification of proteins structures)2GD7    3S9G   
SuperfamilyO94992
Human Protein AtlasENSG00000186834
Peptide AtlasO94992
HPRD09544
IPIIPI00007941   
Protein Interaction databases
DIP (DOE-UCLA)O94992
IntAct (EBI)O94992
FunCoupENSG00000186834
BioGRIDHEXIM1
STRING (EMBL)HEXIM1
ZODIACHEXIM1
Ontologies - Pathways
QuickGOO94992
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  cyclin-dependent protein serine/threonine kinase inhibitor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  heart development  snRNA binding  negative regulation of cyclin-dependent protein serine/threonine kinase activity  negative regulation of transcription, DNA-templated  7SK snRNA binding  positive regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  cyclin-dependent protein serine/threonine kinase inhibitor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  heart development  snRNA binding  negative regulation of cyclin-dependent protein serine/threonine kinase activity  negative regulation of transcription, DNA-templated  7SK snRNA binding  positive regulation of signal transduction by p53 class mediator  
NDEx NetworkHEXIM1
Atlas of Cancer Signalling NetworkHEXIM1
Wikipedia pathwaysHEXIM1
Orthology - Evolution
OrthoDB10614
GeneTree (enSembl)ENSG00000186834
Phylogenetic Trees/Animal Genes : TreeFamHEXIM1
HOVERGENO94992
HOGENOMO94992
Homologs : HomoloGeneHEXIM1
Homology/Alignments : Family Browser (UCSC)HEXIM1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHEXIM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HEXIM1
dbVarHEXIM1
ClinVarHEXIM1
1000_GenomesHEXIM1 
Exome Variant ServerHEXIM1
ExAC (Exome Aggregation Consortium)HEXIM1 (select the gene name)
Genetic variants : HAPMAP10614
Genomic Variants (DGV)HEXIM1 [DGVbeta]
DECIPHER (Syndromes)17:43224684-43229468  ENSG00000186834
CONAN: Copy Number AnalysisHEXIM1 
Mutations
ICGC Data PortalHEXIM1 
TCGA Data PortalHEXIM1 
Broad Tumor PortalHEXIM1
OASIS PortalHEXIM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHEXIM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHEXIM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HEXIM1
DgiDB (Drug Gene Interaction Database)HEXIM1
DoCM (Curated mutations)HEXIM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HEXIM1 (select a term)
intoGenHEXIM1
Cancer3DHEXIM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607328   
Orphanet
MedgenHEXIM1
Genetic Testing Registry HEXIM1
NextProtO94992 [Medical]
TSGene10614
GENETestsHEXIM1
Huge Navigator HEXIM1 [HugePedia]
snp3D : Map Gene to Disease10614
BioCentury BCIQHEXIM1
ClinGenHEXIM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10614
Chemical/Pharm GKB GenePA142671694
Clinical trialHEXIM1
Miscellaneous
canSAR (ICR)HEXIM1 (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHEXIM1
EVEXHEXIM1
GoPubMedHEXIM1
iHOPHEXIM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:08:55 CET 2017

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