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HEXIM2 (hexamethylene bisacetamide inducible 2)

Identity

Alias_nameshexamethylene bis-acetamide inducible 2
Alias_symbol (synonym)FLJ32384
Other aliasL3
HGNC (Hugo) HEXIM2
LocusID (NCBI) 124790
Atlas_Id 54358
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 45160174 and ends at 45170040 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HEXIM2 (17q21.31) / NMT1 (17q21.31)HEXIM2 (17q21.31) / UBE2D2 (5q31.2)MTMR3 (22q12.2) / HEXIM2 (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HEXIM2   28591
Cards
Entrez_Gene (NCBI)HEXIM2  124790  hexamethylene bisacetamide inducible 2
AliasesL3
GeneCards (Weizmann)HEXIM2
Ensembl hg19 (Hinxton)ENSG00000168517 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168517 [Gene_View]  chr17:45160174-45170040 [Contig_View]  HEXIM2 [Vega]
ICGC DataPortalENSG00000168517
TCGA cBioPortalHEXIM2
AceView (NCBI)HEXIM2
Genatlas (Paris)HEXIM2
WikiGenes124790
SOURCE (Princeton)HEXIM2
Genetics Home Reference (NIH)HEXIM2
Genomic and cartography
GoldenPath hg38 (UCSC)HEXIM2  -     chr17:45160174-45170040 +  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HEXIM2  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblHEXIM2 - 17q21.31 [CytoView hg19]  HEXIM2 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIHEXIM2 [Mapview hg19]  HEXIM2 [Mapview hg38]
OMIM615695   
Gene and transcription
Genbank (Entrez)AA223138 AK056946 AW340131 AY598322 BC003531
RefSeq transcript (Entrez)NM_001303436 NM_001303437 NM_001303438 NM_001303439 NM_001303440 NM_001303441 NM_001303442 NM_001303443 NM_001303444 NM_144608
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HEXIM2
Cluster EST : UnigeneHs.594840 [ NCBI ]
CGAP (NCI)Hs.594840
Alternative Splicing GalleryENSG00000168517
Gene ExpressionHEXIM2 [ NCBI-GEO ]   HEXIM2 [ EBI - ARRAY_EXPRESS ]   HEXIM2 [ SEEK ]   HEXIM2 [ MEM ]
Gene Expression Viewer (FireBrowse)HEXIM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124790
GTEX Portal (Tissue expression)HEXIM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MH2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MH2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MH2
Splice isoforms : SwissVarQ96MH2
PhosPhoSitePlusQ96MH2
Domains : Interpro (EBI)HEXIM    HEXIM2   
Domain families : Pfam (Sanger)HEXIM (PF15313)   
Domain families : Pfam (NCBI)pfam15313   
Conserved Domain (NCBI)HEXIM2
DMDM Disease mutations124790
Blocks (Seattle)HEXIM2
SuperfamilyQ96MH2
Human Protein AtlasENSG00000168517
Peptide AtlasQ96MH2
HPRD08129
IPIIPI00180465   
Protein Interaction databases
DIP (DOE-UCLA)Q96MH2
IntAct (EBI)Q96MH2
FunCoupENSG00000168517
BioGRIDHEXIM2
STRING (EMBL)HEXIM2
ZODIACHEXIM2
Ontologies - Pathways
QuickGOQ96MH2
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  cyclin-dependent protein serine/threonine kinase inhibitor activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  transcription, DNA-templated  nuclear speck  snRNA binding  identical protein binding  negative regulation of cyclin-dependent protein serine/threonine kinase activity  negative regulation of transcription, DNA-templated  7SK snRNA binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  cyclin-dependent protein serine/threonine kinase inhibitor activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  transcription, DNA-templated  nuclear speck  snRNA binding  identical protein binding  negative regulation of cyclin-dependent protein serine/threonine kinase activity  negative regulation of transcription, DNA-templated  7SK snRNA binding  
NDEx NetworkHEXIM2
Atlas of Cancer Signalling NetworkHEXIM2
Wikipedia pathwaysHEXIM2
Orthology - Evolution
OrthoDB124790
GeneTree (enSembl)ENSG00000168517
Phylogenetic Trees/Animal Genes : TreeFamHEXIM2
HOVERGENQ96MH2
HOGENOMQ96MH2
Homologs : HomoloGeneHEXIM2
Homology/Alignments : Family Browser (UCSC)HEXIM2
Gene fusions - Rearrangements
Fusion : MitelmanMTMR3/HEXIM2 [22q12.2/17q21.31]  [t(17;22)(q21;q12)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHEXIM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HEXIM2
dbVarHEXIM2
ClinVarHEXIM2
1000_GenomesHEXIM2 
Exome Variant ServerHEXIM2
ExAC (Exome Aggregation Consortium)HEXIM2 (select the gene name)
Genetic variants : HAPMAP124790
Genomic Variants (DGV)HEXIM2 [DGVbeta]
DECIPHERHEXIM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHEXIM2 
Mutations
ICGC Data PortalHEXIM2 
TCGA Data PortalHEXIM2 
Broad Tumor PortalHEXIM2
OASIS PortalHEXIM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHEXIM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHEXIM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HEXIM2
DgiDB (Drug Gene Interaction Database)HEXIM2
DoCM (Curated mutations)HEXIM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HEXIM2 (select a term)
intoGenHEXIM2
Cancer3DHEXIM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615695   
Orphanet
MedgenHEXIM2
Genetic Testing Registry HEXIM2
NextProtQ96MH2 [Medical]
TSGene124790
GENETestsHEXIM2
Target ValidationHEXIM2
Huge Navigator HEXIM2 [HugePedia]
snp3D : Map Gene to Disease124790
BioCentury BCIQHEXIM2
ClinGenHEXIM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD124790
Chemical/Pharm GKB GenePA142671695
Clinical trialHEXIM2
Miscellaneous
canSAR (ICR)HEXIM2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHEXIM2
EVEXHEXIM2
GoPubMedHEXIM2
iHOPHEXIM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:36:42 CEST 2017

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