Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HIF3A (hypoxia inducible factor 3 alpha subunit)

Identity

Alias_symbol (synonym)IPAS
MOP7
PASD7
bHLHe17
Other aliasHIF-3A
HIF3-alpha-1
HGNC (Hugo) HIF3A
LocusID (NCBI) 64344
Atlas_Id 47300
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 46801633 and ends at 46846690 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIF3A   15825
Cards
Entrez_Gene (NCBI)HIF3A  64344  hypoxia inducible factor 3 alpha subunit
AliasesHIF-3A; HIF3-alpha-1; IPAS; MOP7; 
PASD7; bHLHe17
GeneCards (Weizmann)HIF3A
Ensembl hg19 (Hinxton)ENSG00000124440 [Gene_View]  chr19:46801633-46846690 [Contig_View]  HIF3A [Vega]
Ensembl hg38 (Hinxton)ENSG00000124440 [Gene_View]  chr19:46801633-46846690 [Contig_View]  HIF3A [Vega]
ICGC DataPortalENSG00000124440
TCGA cBioPortalHIF3A
AceView (NCBI)HIF3A
Genatlas (Paris)HIF3A
WikiGenes64344
SOURCE (Princeton)HIF3A
Genetics Home Reference (NIH)HIF3A
Genomic and cartography
GoldenPath hg19 (UCSC)HIF3A  -     chr19:46801633-46846690 +  19q13.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HIF3A  -     19q13.32   [Description]    (hg38-Dec_2013)
EnsemblHIF3A - 19q13.32 [CytoView hg19]  HIF3A - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIHIF3A [Mapview hg19]  HIF3A [Mapview hg38]
OMIM609976   
Gene and transcription
Genbank (Entrez)AB054067 AB118749 AB295039 AF079154 AF463492
RefSeq transcript (Entrez)NM_022462 NM_152794 NM_152795 NM_152796
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_029679 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)HIF3A
Cluster EST : UnigeneHs.420830 [ NCBI ]
CGAP (NCI)Hs.420830
Alternative Splicing GalleryENSG00000124440
Gene ExpressionHIF3A [ NCBI-GEO ]   HIF3A [ EBI - ARRAY_EXPRESS ]   HIF3A [ SEEK ]   HIF3A [ MEM ]
Gene Expression Viewer (FireBrowse)HIF3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64344
GTEX Portal (Tissue expression)HIF3A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2N7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2N7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2N7
Splice isoforms : SwissVarQ9Y2N7
PhosPhoSitePlusQ9Y2N7
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)    PAS (PS50112)   
Domains : Interpro (EBI)bHLH_dom    HIF_alpha_subunit    PAC    PAS    PAS_fold   
Domain families : Pfam (Sanger)HIF-1 (PF11413)    PAS (PF00989)   
Domain families : Pfam (NCBI)pfam11413    pfam00989   
Domain families : Smart (EMBL)HLH (SM00353)  PAC (SM00086)  PAS (SM00091)  
Conserved Domain (NCBI)HIF3A
DMDM Disease mutations64344
Blocks (Seattle)HIF3A
PDB (SRS)4WN5   
PDB (PDBSum)4WN5   
PDB (IMB)4WN5   
PDB (RSDB)4WN5   
Structural Biology KnowledgeBase4WN5   
SCOP (Structural Classification of Proteins)4WN5   
CATH (Classification of proteins structures)4WN5   
SuperfamilyQ9Y2N7
Human Protein AtlasENSG00000124440
Peptide AtlasQ9Y2N7
HPRD17104
IPIIPI00292048   IPI00470784   IPI00746815   IPI00844320   IPI00164458   IPI00844043   IPI00908806   IPI00908371   IPI01008729   IPI01025620   IPI00386973   IPI00982249   IPI00738729   IPI00979602   IPI00976505   IPI00975828   IPI01009010   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2N7
IntAct (EBI)Q9Y2N7
FunCoupENSG00000124440
BioGRIDHIF3A
STRING (EMBL)HIF3A
ZODIACHIF3A
Ontologies - Pathways
QuickGOQ9Y2N7
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  angiogenesis  DNA binding  transcription coactivator activity  transcription corepressor activity  nucleoplasm  mitochondrion  cytosol  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  apoptotic process  nuclear speck  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of transcription from RNA polymerase II promoter in response to hypoxia  cellular response to hypoxia  negative regulation of nucleic acid-templated transcription  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  angiogenesis  DNA binding  transcription coactivator activity  transcription corepressor activity  nucleoplasm  mitochondrion  cytosol  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  apoptotic process  nuclear speck  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of transcription from RNA polymerase II promoter in response to hypoxia  cellular response to hypoxia  negative regulation of nucleic acid-templated transcription  
NDEx NetworkHIF3A
Atlas of Cancer Signalling NetworkHIF3A
Wikipedia pathwaysHIF3A
Orthology - Evolution
OrthoDB64344
GeneTree (enSembl)ENSG00000124440
Phylogenetic Trees/Animal Genes : TreeFamHIF3A
HOVERGENQ9Y2N7
HOGENOMQ9Y2N7
Homologs : HomoloGeneHIF3A
Homology/Alignments : Family Browser (UCSC)HIF3A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIF3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIF3A
dbVarHIF3A
ClinVarHIF3A
1000_GenomesHIF3A 
Exome Variant ServerHIF3A
ExAC (Exome Aggregation Consortium)HIF3A (select the gene name)
Genetic variants : HAPMAP64344
Genomic Variants (DGV)HIF3A [DGVbeta]
DECIPHER (Syndromes)19:46801633-46846690  ENSG00000124440
CONAN: Copy Number AnalysisHIF3A 
Mutations
ICGC Data PortalHIF3A 
TCGA Data PortalHIF3A 
Broad Tumor PortalHIF3A
OASIS PortalHIF3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIF3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIF3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIF3A
DgiDB (Drug Gene Interaction Database)HIF3A
DoCM (Curated mutations)HIF3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIF3A (select a term)
intoGenHIF3A
Cancer3DHIF3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609976   
Orphanet
MedgenHIF3A
Genetic Testing Registry HIF3A
NextProtQ9Y2N7 [Medical]
TSGene64344
GENETestsHIF3A
Huge Navigator HIF3A [HugePedia]
snp3D : Map Gene to Disease64344
BioCentury BCIQHIF3A
ClinGenHIF3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64344
Chemical/Pharm GKB GenePA29285
Clinical trialHIF3A
Miscellaneous
canSAR (ICR)HIF3A (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIF3A
EVEXHIF3A
GoPubMedHIF3A
iHOPHIF3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:09:00 CET 2017

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