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HIGD1A (HIG1 hypoxia inducible domain family member 1A)

Identity

Other namesHIG1
RCF1a
HGNC (Hugo) HIGD1A
LocusID (NCBI) 25994
Atlas_Id 46646
Location 3p22.1  [Link to chromosome band 3p22]
Location_base_pair Starts at 42824400 and ends at 42845934 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CCNE1 (19q12) / HIGD1A (3p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Nodular lymphocyte-predominant Hodgkin lymphoma

External links

Nomenclature
HGNC (Hugo)HIGD1A   29527
Cards
Entrez_Gene (NCBI)HIGD1A  25994  HIG1 hypoxia inducible domain family member 1A
AliasesHIG1; RCF1a
GeneCards (Weizmann)HIGD1A
Ensembl hg19 (Hinxton)ENSG00000181061 [Gene_View]  chr3:42824400-42845934 [Contig_View]  HIGD1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000181061 [Gene_View]  chr3:42824400-42845934 [Contig_View]  HIGD1A [Vega]
ICGC DataPortalENSG00000181061
TCGA cBioPortalHIGD1A
AceView (NCBI)HIGD1A
Genatlas (Paris)HIGD1A
WikiGenes25994
SOURCE (Princeton)HIGD1A
Genomic and cartography
GoldenPath hg19 (UCSC)HIGD1A  -     chr3:42824400-42845934 -  3p22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HIGD1A  -     3p22.1   [Description]    (hg38-Dec_2013)
EnsemblHIGD1A - 3p22.1 [CytoView hg19]  HIGD1A - 3p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIGD1A [Mapview hg19]  HIGD1A [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF077034 AF145385 AK225461 AK225571 AK311815
RefSeq transcript (Entrez)NM_001099668 NM_001099669 NM_014056
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)HIGD1A
Cluster EST : UnigeneHs.728813 [ NCBI ]
CGAP (NCI)Hs.728813
Alternative Splicing GalleryENSG00000181061
Gene ExpressionHIGD1A [ NCBI-GEO ]   HIGD1A [ EBI - ARRAY_EXPRESS ]   HIGD1A [ SEEK ]   HIGD1A [ MEM ]
Gene Expression Viewer (FireBrowse)HIGD1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25994
GTEX Portal (Tissue expression)HIGD1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y241 (Uniprot)
NextProtQ9Y241  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y241
Splice isoforms : SwissVarQ9Y241 (Swissvar)
PhosPhoSitePlusQ9Y241
Domaine pattern : Prosite (Expaxy)HIG1 (PS51503)   
Domains : Interpro (EBI)Hypoxia_induced_domain   
Domain families : Pfam (Sanger)HIG_1_N (PF04588)   
Domain families : Pfam (NCBI)pfam04588   
DMDM Disease mutations25994
Blocks (Seattle)HIGD1A
PDB (SRS)2LOM   
PDB (PDBSum)2LOM   
PDB (IMB)2LOM   
PDB (RSDB)2LOM   
Structural Biology KnowledgeBase2LOM   
SCOP (Structural Classification of Proteins)2LOM   
CATH (Classification of proteins structures)2LOM   
SuperfamilyQ9Y241
Human Protein AtlasENSG00000181061
Peptide AtlasQ9Y241
HPRD13651
IPIIPI00295621   IPI00856008   IPI00926995   IPI00927455   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y241
IntAct (EBI)Q9Y241
FunCoupENSG00000181061
BioGRIDHIGD1A
STRING (EMBL)HIGD1A
ZODIACHIGD1A
Ontologies - Pathways
QuickGOQ9Y241
Ontology : AmiGOmitochondrial inner membrane  integral component of membrane  negative regulation of apoptotic process  protein complex  oxidation-reduction process  respiratory chain  
Ontology : EGO-EBImitochondrial inner membrane  integral component of membrane  negative regulation of apoptotic process  protein complex  oxidation-reduction process  respiratory chain  
NDEx Network
Atlas of Cancer Signalling NetworkHIGD1A
Wikipedia pathwaysHIGD1A
Orthology - Evolution
OrthoDB25994
GeneTree (enSembl)ENSG00000181061
Phylogenetic Trees/Animal Genes : TreeFamHIGD1A
Homologs : HomoloGeneHIGD1A
Homology/Alignments : Family Browser (UCSC)HIGD1A
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerHIGD1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIGD1A
dbVarHIGD1A
ClinVarHIGD1A
1000_GenomesHIGD1A 
Exome Variant ServerHIGD1A
ExAC (Exome Aggregation Consortium)HIGD1A (select the gene name)
Genetic variants : HAPMAP25994
Genomic Variants (DGV)HIGD1A [DGVbeta]
Mutations
ICGC Data PortalHIGD1A 
TCGA Data PortalHIGD1A 
Broad Tumor PortalHIGD1A
OASIS PortalHIGD1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIGD1A 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch HIGD1A
DgiDB (Drug Gene Interaction Database)HIGD1A
DoCM (Curated mutations)HIGD1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIGD1A (select a term)
intoGenHIGD1A
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:42824400-42845934  ENSG00000181061
CONAN: Copy Number AnalysisHIGD1A 
Mutations and Diseases : HGMDHIGD1A
OMIM
MedgenHIGD1A
Genetic Testing Registry HIGD1A
NextProtQ9Y241 [Medical]
TSGene25994
GENETestsHIGD1A
Huge Navigator HIGD1A [HugePedia]
snp3D : Map Gene to Disease25994
BioCentury BCIQHIGD1A
ClinGenHIGD1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25994
Chemical/Pharm GKB GenePA142671681
Clinical trialHIGD1A
Miscellaneous
canSAR (ICR)HIGD1A (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIGD1A
EVEXHIGD1A
GoPubMedHIGD1A
iHOPHIGD1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:19:45 CEST 2016

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