Identity
HGNC
LOCATION
5q23.3
LOCUSID
ALIAS
HINT,NMAN,PKCI-1,PRKCNH1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3094
MIM: 601314
HGNC: 4912
Ensembl: ENSG00000169567
Variants:
dbSNP: 3094
ClinVar: 3094
TCGA: ENSG00000169567
COSMIC: HINT1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166123046 | cessation | Disease | ClinicalAnnotation | associated | |||
| PA445876 | Tobacco Use Disorder | Disease | ClinicalAnnotation | associated | PD | 17978999 | |
| PA450626 | nicotine | Chemical | ClinicalAnnotation | associated | PD | 17978999 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38279213 | 2024 | The HINT1 Gene rs2526303 Polymorphism and Its Association with Personality Traits in Cigarette Smokers. | 1 |
| 39062900 | 2024 | HINT1 Gene Polymorphisms, Smoking Behaviour, and Personality Traits: A Haplotype Case-Control Study. | 0 |
| 38279213 | 2024 | The HINT1 Gene rs2526303 Polymorphism and Its Association with Personality Traits in Cigarette Smokers. | 1 |
| 39062900 | 2024 | HINT1 Gene Polymorphisms, Smoking Behaviour, and Personality Traits: A Haplotype Case-Control Study. | 0 |
| 37373392 | 2023 | Association of the rs3864283 Polymorphism Located in the HINT1 Gene with Cigarette Use and Personality Traits. | 1 |
| 37373392 | 2023 | Association of the rs3864283 Polymorphism Located in the HINT1 Gene with Cigarette Use and Personality Traits. | 1 |
| 35054788 | 2022 | Intracellular HINT1-Assisted Hydrolysis of Nucleoside 5'-O-Selenophosphate Leads to the Release of Hydrogen Selenide That Exhibits Toxic Effects in Human Cervical Cancer Cells. | 4 |
| 35241097 | 2022 | Integrated analysis of ceRNA network reveals potential prognostic Hint1-related lncRNAs involved in hepatocellular carcinoma progression. | 1 |
| 36242072 | 2022 | HINT1 neuropathy in Lithuania: clinical, genetic, and functional profiling. | 0 |
| 35054788 | 2022 | Intracellular HINT1-Assisted Hydrolysis of Nucleoside 5'-O-Selenophosphate Leads to the Release of Hydrogen Selenide That Exhibits Toxic Effects in Human Cervical Cancer Cells. | 4 |
| 35241097 | 2022 | Integrated analysis of ceRNA network reveals potential prognostic Hint1-related lncRNAs involved in hepatocellular carcinoma progression. | 1 |
| 36242072 | 2022 | HINT1 neuropathy in Lithuania: clinical, genetic, and functional profiling. | 0 |
| 33404983 | 2021 | Human HINT1 Mutant Proteins that Cause Axonal Motor Neuropathy Exhibit Anomalous Interactions with Partner Proteins. | 3 |
| 33663550 | 2021 | HINT1 neuropathy in Norway: clinical, genetic and functional profiling. | 7 |
| 34098726 | 2021 | HINT1 (Histidine Triad Nucleotide-Binding Protein 1) Attenuates Cardiac Hypertrophy Via Suppressing HOXA5 (Homeobox A5) Expression. | 13 |
Citation
Dessen P
HINT1 (histidine triad nucleotide binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-08-01
Online version: http://atlasgeneticsoncology.org/gene/51577/hint1
