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HINT3 (histidine triad nucleotide binding protein 3)

Identity

Alias_symbol (synonym)FLJ33126
Other aliasHINT4
HGNC (Hugo) HINT3
LocusID (NCBI) 135114
Atlas_Id 64272
Location 6q22.32  [Link to chromosome band 6q22]
Location_base_pair Starts at 125956715 and ends at 125980243 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HINT3 (6q22.32) / NCOA7 (6q22.32)LYZ (12q15) / HINT3 (6q22.32)TRMT11 (6q22.32) / HINT3 (6q22.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(q22;q22) TRMT11/HINT3


External links

Nomenclature
HGNC (Hugo)HINT3   18468
Cards
Entrez_Gene (NCBI)HINT3  135114  histidine triad nucleotide binding protein 3
AliasesHINT4
GeneCards (Weizmann)HINT3
Ensembl hg19 (Hinxton)ENSG00000111911 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111911 [Gene_View]  ENSG00000111911 [Sequence]  chr6:125956715-125980243 [Contig_View]  HINT3 [Vega]
ICGC DataPortalENSG00000111911
TCGA cBioPortalHINT3
AceView (NCBI)HINT3
Genatlas (Paris)HINT3
WikiGenes135114
SOURCE (Princeton)HINT3
Genetics Home Reference (NIH)HINT3
Genomic and cartography
GoldenPath hg38 (UCSC)HINT3  -     chr6:125956715-125980243 +  6q22.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HINT3  -     6q22.32   [Description]    (hg19-Feb_2009)
EnsemblHINT3 - 6q22.32 [CytoView hg19]  HINT3 - 6q22.32 [CytoView hg38]
Mapping of homologs : NCBIHINT3 [Mapview hg19]  HINT3 [Mapview hg38]
OMIM609998   
Gene and transcription
Genbank (Entrez)AJ420577 AK056858 AK057688 AK309857 AY035387
RefSeq transcript (Entrez)NM_138571
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HINT3
Cluster EST : UnigeneHs.72325 [ NCBI ]
CGAP (NCI)Hs.72325
Alternative Splicing GalleryENSG00000111911
Gene ExpressionHINT3 [ NCBI-GEO ]   HINT3 [ EBI - ARRAY_EXPRESS ]   HINT3 [ SEEK ]   HINT3 [ MEM ]
Gene Expression Viewer (FireBrowse)HINT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)135114
GTEX Portal (Tissue expression)HINT3
Human Protein AtlasENSG00000111911-HINT3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQE9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQE9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQE9
Splice isoforms : SwissVarQ9NQE9
PhosPhoSitePlusQ9NQE9
Domaine pattern : Prosite (Expaxy)HIT_2 (PS51084)   
Domains : Interpro (EBI)HIT-like   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)HINT3
DMDM Disease mutations135114
Blocks (Seattle)HINT3
SuperfamilyQ9NQE9
Human Protein Atlas [tissue]ENSG00000111911-HINT3 [tissue]
Peptide AtlasQ9NQE9
HPRD17107
IPIIPI00170924   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQE9
IntAct (EBI)Q9NQE9
FunCoupENSG00000111911
BioGRIDHINT3
STRING (EMBL)HINT3
ZODIACHINT3
Ontologies - Pathways
QuickGOQ9NQE9
Ontology : AmiGOnucleotide binding  nucleus  cytoplasm  hydrolase activity  extracellular exosome  
Ontology : EGO-EBInucleotide binding  nucleus  cytoplasm  hydrolase activity  extracellular exosome  
NDEx NetworkHINT3
Atlas of Cancer Signalling NetworkHINT3
Wikipedia pathwaysHINT3
Orthology - Evolution
OrthoDB135114
GeneTree (enSembl)ENSG00000111911
Phylogenetic Trees/Animal Genes : TreeFamHINT3
HOVERGENQ9NQE9
HOGENOMQ9NQE9
Homologs : HomoloGeneHINT3
Homology/Alignments : Family Browser (UCSC)HINT3
Gene fusions - Rearrangements
Fusion : QuiverHINT3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHINT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HINT3
dbVarHINT3
ClinVarHINT3
1000_GenomesHINT3 
Exome Variant ServerHINT3
ExAC (Exome Aggregation Consortium)ENSG00000111911
GNOMAD BrowserENSG00000111911
Varsome BrowserHINT3
Genetic variants : HAPMAP135114
Genomic Variants (DGV)HINT3 [DGVbeta]
DECIPHERHINT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHINT3 
Mutations
ICGC Data PortalHINT3 
TCGA Data PortalHINT3 
Broad Tumor PortalHINT3
OASIS PortalHINT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHINT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHINT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HINT3
DgiDB (Drug Gene Interaction Database)HINT3
DoCM (Curated mutations)HINT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HINT3 (select a term)
intoGenHINT3
Cancer3DHINT3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609998   
Orphanet
DisGeNETHINT3
MedgenHINT3
Genetic Testing Registry HINT3
NextProtQ9NQE9 [Medical]
TSGene135114
GENETestsHINT3
Target ValidationHINT3
Huge Navigator HINT3 [HugePedia]
snp3D : Map Gene to Disease135114
BioCentury BCIQHINT3
ClinGenHINT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD135114
Chemical/Pharm GKB GenePA29288
Clinical trialHINT3
Miscellaneous
canSAR (ICR)HINT3 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHINT3
EVEXHINT3
GoPubMedHINT3
iHOPHINT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:48:52 CEST 2018

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